■ 学術雑誌
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原著
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1.
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Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, Matsumoto A, Yamaguchi K, Isobe Y, Tsuchiya A, Shikata S, Sato N, Morinaga H, Fukuyama T, Tanaka Y, Fukushima T, Takeda R, Yamamoto K, Honda H, Nishimura E, Furukawa Y, Shibata T, Abdel-Wahab O, Suematsu M, Kitamura T.：
Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.
Nature Commun
12
(1)
：1826
, 2021.3
DOI:doi: 10.1038/s41467-021-22053-y.
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2.
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Sera Y, Nakata Y, Takeshi Ueda T, Yamasaki N, Koide S, Kobayashi H, Ikeda Ki, Kobatake K, Iwasaki M, Oda H, Wolff L, Kanai A, Nagamachi A, Inaba T, Sotomaru Y, Ichinohe T, Koizumi M, Miyakawa Y, Honda Zi, Iwama A, Suda T, Takubo K, Honda H.：
UTX maintains functional integrity of murine hematopoietic system by globally regulating aging-associated genes.
Blood
137
(7)
：908-922
, 2021.2
DOI:doi: 10.1182/blood.2019001044.
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3.
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Sera Yasuyuki†, Nakata yuichiro, Ueda Takeshi, Yamasaki norimasa, Koide shuhei, Kobayashi hiroshi, Ikeda kenichiro, Kobatake Kohei, Iwasaki Masayuki, Oda Hideaki, Wolff Linda, Kanai Akinori, Nagamachi Akiko, Inaba Toshiya, Sotomaru Yusuke, Ichinohe Tatsuo, Koizumi Miho, Miyakawa Yoshihiko, Honda Zenichiro, Iwama Atsushi, Suda Toshio, Takubo Keiyo, Honda Hiroaki：
UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes.
Blood
137
(7)
：908-922
, 2021.2
DOI:10.1182/blood.2019001044
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4.
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Inoue A, Kiyoshima T, Yoshizaki K, Nakatomi C, Nakatomi M, Ohshima H, Shin M, Gao J, Tsuru K, Okabe K, Nakamura I, Honda H, Matsuda M, Takahashi I, Jimi E.：
Deletion of epithelial cell-specific p130Cas impairs the maturation stage of amelogenesis.
Bone
154
：116210
, 2021.1
DOI:doi: 10.1016/j.bone.2021.116210.
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5.
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Watanabe A, Miyake K, Nordlund J, Syvänen AC, van der Weyden L, Honda H, Yamazaki N, Nagamachi A, Inaba T, Ikawa T, Urayama KY, Kiyokawa N, Ohara A, Kimura S, Kubota Y, Takita J, Goto H, Sakaguchi K, Minegishi M, Iwamoto S, Shinohara T, Kagami K, Abe M, Akahane K, Goi K, Sugita K, Inukai T.：
Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL.
Blood
136
(20)
：2319-2333
, 2020.11
DOI:doi: 10.1182/blood.2019004090
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6.
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Takeda R, Asada S, Park SJ, Yokoyama A, Becker H, Kanai A, Visconte V, Hershberger C, Hayashi Y, Yonezawa T, Tamura M, Fukushima T, Tanaka Y, Fukuyama T, Matsumoto A, Yamasaki S, Nakai K, Yamazaki S, Inaba T, Shibata T, Inoue D, Honda H, Goyama S, Maciejewski J, Kitamura T.：
HHEX promotes myeloid transformation in cooperation with mutant ASXL1.
Blood
136
(14)
：1670-1684
, 2020.10
DOI:doi: 10.1182/blood.2019004613.
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7.
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Iwagawa T, Honda H, Watanabe S.：
Jmjd3 plays pivotal roles in the proper development of early-born retinal lineages, amacrine, horizontal, and retinal ganglion cells.
Invest Ophthalmol Vis Sci
61
(11)
：43-43
, 2020.9
DOI:doi: 10.1167/iovs.61.11.43.
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8.
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HARACHI Mio†, MASUI Kenta*, HONDA Hiroaki, MURAGAKI Yoshihiro, KAWAMATA Takakazu, CAVENEE Webster K., MISCHEL Paul S., SHIBATA Noriyuki：
Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM.
Mol Cancer Res
18
(8)
：1142-1152
, 2020.8
DOI:10.1158/1541-7786.MCR-20-0024
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9.
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Nishimura Toshinobu, Xu Haojun, Iwasaki Masayuki, Karigane Daiki, Saavedra Brandon, Takahashi Yusuke, Suchy Fabian P, Monobe Shinichiro, Martin Renata M, Ohtaka Manami, Nakanishi Mahito, Burrows Scott R, Cleary Michael L, Majeti Ravindra, Shibuya Akira, Nakauchi Hiromitsu：
Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells.
Gene therapy
27
(10-11)
：525-534
, 2020.7
DOI:10.1038/s41434-020-0179-z
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10.
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Umutoni D, Iwagawa T, Baba Y, Tsuhako A, Honda H, Aihara M, Watanabe S.：
H3K27me3 demethylase UTX regulates the differentiation of a subset of bipolar cells in the mouse retina.
Genes Cells
25
(6)
：402-412
, 2020.6
DOI:doi: 10.1111/gtc.12767.
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11.
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Islam S, Chuensirikulchai K, Khummuang S, Keratibumrungpong T, Kongtawelert P, Kasinrerk W, Hatano S, Nagamachi A, Honda H, Watanabe H.：
Accumulation of versican facilitates wound healing: implication of its initial ADAMTS-cleavage site.
Matrix Biol
87
：77-93
, 2020.5
DOI:doi: 10.1016/j.matbio. 2019.10.006.
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12.
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Kobatake K†, Ikeda Ki, Nakata Y, Yamasaki N, Ueda T, Kanai A, Sentani K, Sera Y, Hayashi T, Koizumi M, Miyakawa Y, Inaba T, Sotomaru Y, Kaminuma O, Ichinohe T, Honda Zi, Yasui W, Horie S, Black PC, Matsubara A, Honda H*.：
Kdm6a deficiency activates inflammatory pathways, promotes M2 macrophage polarization, and causes bladder cancer in cooperation with p53 dysfunction.
Clin Can Res
26
(8)
：2065-2079
, 2020.4
DOI:10.1158/1078-0432.CCR-19-2230
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13.
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Kobayakawa M, Matsubara T, Mizokami A, Hiura F, Takakura N, Kokabu S, Matsuda M, Yasuda, H Nakamura I, Takei Y, Honda H, Hosokawa R, Jimi E.：
Kif1c regulates osteoclastic bone resorption as a downstream molecule of p130Cas.
Cell Biochem Funct
38
(3)
：300-308
, 2020.4
DOI:doi: 10.1002/cbf.3476.
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14.
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Takeda R†, *Asada S, Park SJ, Yokoyama A, Becker H, Kanai A, Visconte V, Hershberger C, Hayashi Y, Yonezawa T, Tamura M, Fukushima T, Tanaka Y, Fukuyama T, Matsumoto A, Yamasaki S, Nakai K, Yamazaki S, Inaba T, Shibata T, Inoue D, Honda H, Goyama S, Maciejewski J, Kitamura T.：
HHEX promotes myeloid transformation in cooperation with mutant ASXL1.
Blood
136
(14)
：1670-1684
, 2020
DOI:10.1182/blood.2019004613
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|
15.
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Watanabe A†, Miyake K, Nordlund J, Syvänen AC, van der Weyden L, Honda H, Yamazaki N, Nagamachi A, Inaba T, Ikawa T, Urayama KY, Kiyokawa N, Ohara A, Kimura S, Kubota Y, Takita J, Goto H, Sakaguchi K, Minegishi M, Iwamoto S, Shinohara T, Kagami K, Abe M, Akahane K, Goi K, Sugita K, Inukai T*.：
Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL.
Blood
136
(20)
：2319-2333
, 2020
DOI:10.1182/blood.2019004090
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16.
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Kobayakawa M†, Matsubara T, Mizokami A, Hiura F, Takakura N, Kokabu S, Matsuda M, Yasuda, H Nakamura I, Takei Y, Honda H, Hosokawa R, Jimi E*.：
Kif1c regulates osteoclastic bone resorption as a downstream molecule of p130Cas.
Cell Biochem Funct
38
(3)
：300-308
, 2020
DOI:10.1002/cbf.3476
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17.
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Umutoni D†, Iwagawa T, Baba Y, Tsuhako A, Honda H, Aihara M, Watanabe S*.：
H3K27me3 demethylase UTX regulates the differentiation of a subset of bipolar cells in the mouse retina.
Genes Cells
25
(6)
：402-412
, 2020
DOI:10.1111/gtc.12767.
|
|
18.
|
Iwagawa T†, Honda H, Watanabe S*.：
Jmjd3 plays pivotal roles in the proper development of early-born retinal lineages, amacrine, horizontal, and retinal ganglion cells.
Invest Ophthalmol Vis Sci
61
(11)
：43
, 2020
DOI:10.1167/iovs.61.11.43
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|
19.
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Islam S†, Chuensirikulchai K, Khummuang S, Keratibumrungpong T, Kongtawelert P, Kasinrerk W, Hatano S, Nagamachi A, Honda H, Watanabe H*.：
Accumulation of versican facilitates wound healing: implication of its initial ADAMTS-cleavage site.
Matrix Biol
87
：77-93
, 2020
DOI:10.1016/j.matbio. 2019.10.006
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