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 血液内科
概要 当該年度の研究費受入状況 当該年度の主催学会・研究会
学術雑誌 著書 学会発表


教授:
   田中 淳司
准教授:
   志関 雅幸
講師:
   萩原 將太郎
   吉永 健太郎
助教:
   風間 啓至
   篠原 明仁
   飯塚 有希
   石山 みどり
   田中 紀奈
   渡邉 彩
■ 概要
特徴
白血病、骨髄異形成症候群、悪性リンパ腫、骨髄腫などの造血器腫瘍、再生不良性貧血や特発性血小板減少性紫斑病などの幅広い血液疾患について、分子標的療法や造血幹細胞移植を含め、最先端の最良の医療を提供しております。
研究
白血病や骨髄異形成症候群、骨髄腫などの病態に関する分子学的機序や薬剤耐性機序の解明・耐性克服、血液難治性疾患の根治を目指した分子標的療法、造血細胞移植、細胞療法の開発に関する研究をすすめております。
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■ 当該年度の研究費受入状況
1.  科学研究費助成事業 基盤研究(C)  (研究課題番号:15K08320)
 研究課題:20番染色体長腕上の骨髄異形成症候群疾患関連遺伝子の同定と分子機構の解明  (研究代表者:志関 雅幸)
 研究補助金:1,040,000円  (代表)
2.  平成29年度日本医療研究開発機構(AMED)委託研究開発費 感染症実用化研究事業 エイズ対策実用化研究事業  (研究課題番号:16768708)
 研究課題:日本人に最適化されたエイズ関連悪性リンパ腫の包括的医療体制の確立  (研究分担者:萩原 將太郎)
 研究補助金:845,000円  (分担)
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■ 当該年度の主催学会・研究会
1.  第41回日本鉄バイオサイエンス学会学術集会  (会長 : 田中淳司 )  ,東京  2017/09
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■ 当該年度研究業績数一覧表
学術雑誌 著書 学会発表 その他
発表
和文英文 和文英文 国内国際
筆 頭Corresponding
Author
共 著筆 頭Corresponding
Author
共 著 筆 頭共 著筆 頭共 著 演 者共 演演 者共 演 演 者共 演
 0 0 1 1 1 7  0 1 0 0  15 5  4 6  0 0
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■ 学術雑誌
原著
1. Nosaka Kisato, Iwanaga Masako, Imaizumi Yoshitaka, Ishitsuka Kenji, Ishizawa Kenichi, Ishida Yoji, Amano Masahiro, Ishida Takashi, Uike Naokuni, Utsunomiya Atae, Ohshima Koichi, Kawai Kazuhiro, Tanaka Junji, Tokura Yoshiki, Tobinai Kensei, Watanabe Toshiki, Uchimaru Kaoru, Tsukasaki Kunihiro:  Epidemiological and clinical features of adult T-cell leukemia-lymphoma in Japan, 2010-2011: A nationwide survey.  Cancer science  108 (12) :2478-2486 , 2017.12
2. 小林 武, 大橋 一輝, 原口 京子, 奥山 美樹, 日野 雅之, 田中 淳司, 上田 恭典, 西田 徹也, 熱田 由子, 高梨 美乃子, 飯田 美奈子, 室井 一男, 矢部 普正, 宮村 耕一:  本邦における血縁者ドナーからの末梢血幹細胞の事前採取と凍結保存の現状.  臨床血液  58 (11) :2205-2212 , 2017.11
3. Shiseki Masayuki*, Yoshida Chikashi, Takezako Naoki, Ohwada Akira, Kumagai Takashi, Nishiwaki Kaichi, Horikoshi Akira, Fukuda Tetsuya, Takano Hina, Kouzai Yasuji, Tanaka Junji, Morita Satoshi, Sakamoto Junichi, Sakamaki Hisashi, Inokuchi Koiti:  Dasatinib rapidly induces deep molecular response in chronic-phase chronic myeloid leukemia patients who achieved major molecular response with detectable levels of BCR-ABL1 transcripts by imatinib therapy.  International journal of clinical oncology  22 (5) :972-979 , 2017.10
4. Mizutani Motonori, Takami Akiyoshi, Hara Masahiko, Mizuno Shohei, Yanada Masamitsu, Chou Takaaki, Uchiyama Hitoji, Ohashi Kazuteru, Miyamoto Toshihiro, Ozawa Yukiyasu, Imataki Osamu, Kobayashi Naoki, Uchida Naoyuki, Kanamori Heiwa, Kamimura Tomohiko, Eto Tetsuya, Onizuka Makoto, Tanaka Junji, Atsuta Yoshiko, Yano Shingo:  Comparison of Autologous and Unrelated Transplants for Cytogenetically Normal Acute Myelogenous Leukemia.  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation  23 (9) :1447-1454 , 2017.9
5. Tomizawa Daisuke, Tanaka Shiro, Kondo Tadakazu, Hashii Yoshiko, Arai Yasuyuki, Kudo Kazuko, Taga Takashi, Fukuda Takahiro, Goto Hiroaki, Inagaki Jiro, Koh Katsuyoshi, Ohashi Kazuteru, Ozawa Yukiyasu, Inoue Masami, Kato Koji, Tanaka Junji, Atsuta Yoshiko, Adachi Souichi, Ishida Hiroyuki:  Allogeneic Hematopoietic Stem Cell Transplantation for Adolescents and Young Adults with Acute Myeloid Leukemia.  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation  23 (9) :1515-1522 , 2017.9
6. Mori Jinichi, Yanada Masamitsu, Uchida Naoyuki, Fukuda Takahiro, Sakura Toru, Hidaka Michihiro, Watakabe-Inamoto Kyoko, Kanamori Heiwa, Ogawa Hiroyasu, Ichinohe Tatsuo, Tanaka Junji, Atsuta Yoshiko, Yano Shingo:  Outcomes of Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia Patients with Abnormalities of the Short Arm of Chromosome 17.  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation  23 (8) :1398-1404 , 2017.8
7. Arai Yasuyuki, Kondo Tadakazu, Shigematsu Akio, Tanaka Junji, Ohashi Kazuteru, Fukuda Takahiro, Kawakita Toshiro, Mori Takehiko, Hoshino Takumi, Onizuka Makoto, Ozawa Yukiyasu, Yoshida Shuro, Ueda Yasunori, Mizuno Ishikazu, Atsuta Yoshiko, Mizuta Shuichi:  Increased non-relapse mortality due to high-dose cytarabine plus CY/TBI in BMT/PBSCT for acute lymphoblastic leukaemia in adults.  British journal of haematology  178 (1) :106-111 , 2017.7
8. Shigematsu Akio, Kako Shinichi, Mitsuhashi Kenjiro, Iwato Koji, Uchida Naoyuki, Kanda Yoshinobu, Fukuda Takahiro, Sawa Masashi, Senoo Yasushi, Ogawa Hiroyasu, Miyamura Koichi, Takada Satoru, Nagamura-Inoue Tokiko, Morishima Yasuo, Ichinohe Tatsuo, Atsuta Yoshiko, Mizuta Shuichi, Tanaka Junji:  Allogeneic stem cell transplantation for adult patients with acute lymphoblastic leukemia who had central nervous system involvement: a study from the Adult ALL Working Group of the Japan Society for Hematopoietic Cell Transplantation.  International journal of hematology  105 (6) :805-811 , 2017.6
9. Mori Naoki*, Ohwashi-Miyazaki Mari, Yoshinaga Kentaro, Okada Michiko, Shiseki Masayuki, Motoji Toshiko, Tanaka Junji:  Tumor suppressor gene methylation on the short arm of chromosome 1 in chronic myelogenous leukemia.  European journal of haematology  98 (5) :467-477 , 2017.5
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■ 著書
1. 萩原將太郎:    よくわかる血液内科  1-271.  医学書院,  東京, 2018.1
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■ 学会発表
1. ◎Akihito Shinohara, Satoko Osanai, Yuki Izuka, Kentaro Yoshinaga, Masayuki Shiseki, Junji Tanaka: Herpes zoster after autologous hematopoietic stem cell transplantation without antiviral prophylaxis.  44th Annual Meeting of the EBMT,  Lisbon, Portugal,  2018/03
2. ◎KAITO Y, TAMURA H, SOEDA S, ASAYAMA T, ISHIBASHI M, SASAKI M, HANDA H, IMAI Y, TANAKA J, TANOSAKI S, ITO S, INOKUCHI K: Serum soluble SLAMF7 is correlated with disease progression in multiple myeloma and may affect anti-SLAMF7 antibody therapy.  16th International Myeloma Workshop 2017 in New Delhi,  New Delhi, India,  2018/03
3. ◎ISHIBASHI Mariko, TAMURA Hideto, ASAYAMA Toshio, Kuribayashi-hamada Yasuko, ONODERA Asaka, MORIYA Keiichi, SASAKI Makoto, HANDA Hiroshi, IMAI Yoichi, TANAKA Norina, TANAKA Junji, TANOSAKI Sakae, ITO Shigeki, KOMATSU Norio, Inokuchi Koiti: The new immunoreceptor SLAMF3 promotes aggressive biological and clinical characteristics in multiple myeloma.  59th ASH Anuual Meeting & Exposition,  Atlanta, USA,  2017/12
4. ◎ISHIYAMA Midori, SHISEKI Masayuki, HAGIWARA Shotaro, YOSHINAGA Kentaro, TANAKA Junji: Early increased platelet count is a predictive factor for a long-term response in high-dose dexamethasone treatment for newly-diagnosed immune thrombocytopenia patients.  59th ASH Anuual Meeting & Exposition,  Atlanta, USA,  2017/12
5. ◎AOKI J, ISHIYAMA K, UCHIDA N, FUKUDA T, OHASHI K, HIDAKA M, KOBAYASHI N, SAKURA T, AOTSUKA N, OKUMURA H, ICHINOHE T, TANAKA Junji, ATSUTA Y, YANO S: Outcomes of allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia harboring inv(3)/(q21;q26.2)/t(3;3)(q21;q26.2).  22nd Congress of the European Hematology Association,  Madrid, Spain,  2017/06
6. ◎ISHIBASHI M, TAMURA H, ASAYAMA T, Kuribayashi-hamada Y, ONODERA A, MORIYA K, SASAKI M, HANDA H, IMAI Y, TANAKA Junji, TANOSAKI S, ITO S, INOKUCHI K: Pathophysiological functions and clinical impact of the
new immunoreceptor SLAMF3 in multiple myeloma.  22nd Congress of the European Hematology Association,  Madrid, Spain,  2017/06
7. ◎MORI Naoki, YOSHINAGA Kentaro, OHWASHI-MIYAZAKI Mari, SHISEKI Masayuki, SAKURA Hiroshi, TANAKA Junji: Mutations of the JAK2 gene and cytogenetic abnormalities are predictive of progression to hematological neoplasms in patients with idiopathic leukocytosis.  22nd Congress of the European Hematology Association,  Madrid, Spain,  2017/06
8. ◎SHISEKI Masayuki, ISHII Mayuko, OHWASHI Mari, MORI Naoki, YOSHINAGA Kentaro, TANAKA Junji: Molecular mechanisms and clinical significance of reduced PTPN1 expression in myelodysplastic syndromes.  22nd Congress of the European Hematology Association,  Madrid, Spain,  2017/06
9. ◎YOSHINAGA Kentaro, MORI Naoki, OHWASHI Mari, ISHII Mayuko, SHISEKI Masayuki, TANAKA Junji: Acquired pure red cell aplasia associated with lymphoproliferative diseases in erythropoietin-refractory anemia patients on dialysis.  22nd Congress of the European Hematology Association,  Madrid, Spain,  2017/06
10. ◎Arima N, Yabe T, Tanaka J, Morishima Y, Inoue M, Fukuda T, Ichinohe T, Atsuta Y, Kanda Y.: Comparing the Post-Transplant Graft-Versus-Leukemia Effects by KIR2DL1-Positive NK Cells among HLA-Matched C1/C1 and C1/C2 Pairs.  The 8th JSH International Symposium 2017 in Miyazaki,  Miyazaki, Japan,  2017/05
全件表示(30件)
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  :Corresponding Author
 :筆頭者
◎:発表者