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 実験動物研究所
Summary Research grants & projects Published papers
Academic conference presentation


Professor：

    本田　浩章 		Assistant Professor：
    IWASAKI Masayuki 		Assistant Professor：
    Sera Yasuyuki
■ Summary
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■ Research grants & projects
1.  
 Budget amount：\13,400,000  (Principal investigator)
2.  
 Budget amount：\5,000,000  (Principal investigator)
3.  
 Budget amount：\600,000  (Co-investigator)
4.  
 Budget amount：\17,680,000  (Principal investigator)
5.  
 Budget amount：\4,160,000  (Principal investigator)
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
First authorCorresponding
Author		Co-authorFirst authorCorresponding
Author		Co-author First authorCo-authorFirst authorCo-author PresenterCo-presenterPresenterCo-presenter PresenterCo-presenter
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■ Published papers
Original article
1. †Zhu Z, Yichen W, Ziheng Z, Dighao G, Ming L, Wei L, Enfang S, Gang H, Honda H, *Jian Y.：  The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling.  Aging  11 (24) ：12733-12753 , 2019.12   DOI:10.18632/aging.102599
2. †Fukushima T, Tanaka Y, Hamey FK, Chang CH, Oki T, Asada S, Hayashi Y, Fujino T, Yonezawa T, Takeda R, Kawabata KC, Fukuyama T, Umemoto T, Takubo K, Takizawa H, Goyama S, Ishihama Y, Honda H, Göttgens B, *Kitamura T.：  Discrimination of dormant and active hematopoietic stem cells by G0 markers reveals dormancy regulation by cytoplasmic calcium.  Cell Rep  29 (12) ：4144-4158.e7 , 2019.12   DOI:10.1016/j.celrep.2019.11.061
3. Jeong Johan, Jager Astraea, Domizi Pablo, Pavel-Dinu Mara, Gojenola Linda, Iwasaki Masayuki, Wei Michael C, Pan Feng, Zehnder James L, Porteus Matthew H, Davis Kara L, Cleary Michael L：  High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cells.  Blood advances  3 (19) ：2825-2835 , 2019.10   DOI:10.1182/bloodadvances.2019000450
4. †Miyazaki T, Zhao Z, Ichihara Y, Yoshino D, Imamura T, Sawada K, Hayano S, Kamioka H, Mori S, Hirata H, Araki K, Kawauchi K, Shigemoto K, Tanaka S, Bonewald LF, Honda H, Shinohara M, Nagao M, Ogata T, Harada I, *Sawada Y.：  Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity.  Science Adv  5 (9) ：eaau7802 , 2019.9   DOI:10.1126/sciadv.aau7802
5. †Wada T, Kikuchi J, Koyama D, Honda H, *Furukawa Y.：  Lysine-specific demethylase 1 accelerates oncogenesis in p53 heterozygous mice via transcriptional repression of the residual Trp53 allele.  Leuk Res  82 ：29-32 , 2019.7   DOI:10.1016/j.leukres.2019.05.008
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■ Academic conference presentation
1. 小泉美穂, 三田村佳勇, 世良康如, 本田浩章, 衛藤光, 岸雄介, 藤平篤志： ヒストンの修飾因子UTXの脳特異的な欠損マウスの解析.  第42回日本分子生物学会年会,  福岡,  2019/12
2. 中田雄一郎, 山崎憲政, 神沼修, 本田浩章： DNA損傷修復反応におけるH3K4me3制御の解明.  第42回日本分子生物学会年会,  福岡,  2019/12
3. Iwasaki Masayuki, Honda Hiroaki, Osato Motomi, Cleary Michael： Essential non-canonical role for 15-PGDH in HOX- associated leukemia stem cells.  第81回日本血液学会学術集会,  東京,  2019/10
4. 岩崎正幸： HOX関連白血病幹細胞における15-PGDHの役割.  日本血液学会学術集会,  東京、日本,  2019/10
5. Iwasaki Masayuki , Honda Hiroaki, Osato Motomi, Cleary Michael： Essential non-canonical role for 15-PGDH in MLL-rearranged AML stem cells.  第78回日本癌学会学術総会,  京都,  2019/09
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  ＊：Corresponding Author
 †：First Author
◎：Presenter