Faculty Information - 坂井　晶子

（Last updated : 2024-03-13 16:53:23）

坂井　晶子
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Department of Internal Medicine, Division of Cardiology

Position Assistant Professor

■ Published papers

1.	Original article	Association between myocardial hypoxia and fibrosis in hypertrophic cardiomyopathy: analysis by T2* BOLD and T1 mapping MRI. 2020/03
2.	Original article	Gender differences in predictors of left ventricular myocardial relaxation in non-obese, healthy individuals. 2015/04
3.	Original article	Characteristics of acute congestive heart failure with normal ejection fraction and less elevated B-type natriuretic peptide 2009
4.	Original article	Delayed enhancement on computed tomography in abdominal aortic aneurysm wall. 2007
5.	Original article	Matrix metalloproteinase 2 is suppressed by trapidil, a CD40-CD40 ligand pathway inhibitor, in human abdominal aortic aneurysm wall. 2004
6.	Original article	A 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, cerivastatin, suppresses production of matrix metalloproteinase-9 in human abdominal aortic aneurysm wall. 2002
7.	Original article	An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats. 2002
8.	Original article	Expression of peroxisome proliferator-activated receptor-gamma in vascular smooth muscle cells is upregulated in cystic medial degeneration of annuloaortic ectasia in Marfan syndrome. 2002
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■ Academic conference presentation

1.	Aortic Valve Calcification and Prognostic Evaluation in Patients with Heterozygous Familial Hypercholesterolemia 2021/03
2.	Lipoprotein(a) is residual risk factor for the atherosclerotic cardiovascular disease in patients with LDL-C hypercholesterolemia 2021/03
3.	PCSK9 Gene Mutations Have a Higher Risk of Cardiovascular Events than LDL Receptor Abnoramalities in Heterozygous Familial Hypercholesterolemia 2021/03
4.	Aortic Valve Calcification Predicts Subclinical Coronary Atherosclerosis in Heterozygous Familial Hypercholesterolemia Patients with High LP (a) Levels 2020/07
5.	High Apolipoprotein-B Level is a Risk Factor of Secondary Cardiovascular Incidence in Patients with Familial Hypercholesterolemia 2020/07
6.	Activation of Effector Memory and Effector T Cells in Patients with Familial Hypercholesterolemia. 2019/12/11
7.	Aortic Valve Calcification and Subclinical Coronary Atherosclerosis in Japanese Heterozygous Familial Hypercholesterolemia Patients With High Lp(a) Levels 2019/11/17
8.	Papillary muscle ischemia and global myocardial flow reserve: assessment by highresolution cine imaging of 13N ammonia PET 2019/09/02
9.	Simultaneous analysis of heart and kidney oxygenation using T2 BOLD MRI: investigation of cardiorenal relationship. 2019/05/13
10.	Cardiac Magnetic Resonance T1 Mapping and Late Gadolinium Enhancement Surrogate Major Cardiac Events in Systemic Sclerosis 2019/03/30
11.	Detection of Myocardial Inflammation in Sarcoidosis Using Cardiac Magnetic Resonance T2 Mapping 2019/03/30
12.	Papillary Muscle Ischemia and Global Myocardial Flow Reserve in Coronary Artery Disease: Assessment by High-resolution Cine Imaging of 13Nammonia PET 2019/03/30
13.	Genetic Diagnosis of Familial Hypercholesterolemia and the Risk of Cardiovascular Events 2019/03/29
14.	Prediction of Cardiac Resynchronization Therapy Response in Dilated Cardiomyopathy Using Vortex Flow Mapping on Cine Magnetic Resonance Imaging 2019/03/17
15.	Cardiac sarcoidosis with features mimicking arrhythmogenic right ventricular cardiomyopathy 2019/02/09
16.	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK-9) Inhibitor Improve Lipid Profile and Vascular Atherosclerotic Plaque Formation in Japanese High-Risk Familia Hypercholesterolemia 2018/11/12
17.	Aortic Vale calcification and coronary atherosclerosis in familial hypercholesterolemia patients 2018/09/22
18.	Underdiagnosis and non-treatment of heterozygous familial hypercholesterolemia in association with cardiovascular disease 2018/08/28
19.	Analysis of myocardial fibrosis using cardiac magnetic resonance T1 imaging and late gadolinium enhancement: Association with ventricular tachycardia in hypertrophic cardiomyopathy 2018/08/27
20.	Myocardial oxygenation using T2 BOLD cardiac MRI with compressed SENSE: Association with myocardial fibrosis and contraction in hypertrophic cardiomyopathy. 2018/06/20
21.	Proprotein Convertase Subtilisin/kexin Type 9 (PCSK-9) inhibitors Improve Lipid Profile and Vascular Atherosclerotic Plaque in Familial Hypercholesterolemia 2018/06/09
22.	Analysis of Myocardial Fibrosis Using Cardiac Magnetic Resonance T1 Imaging and Late Gadolinium Enhancement: Association with Ventricular Tachycardia in Hypertrophic Cardiomyopathy 2018/03/25
23.	Analysis of Myocardial Fibrosis Using Cardiac Magnetic Resonance T1 Imaging and Late Gadolinium Enhancement: Association with Ventricular Tachycardia in Hypertrophic Cardiomyopathy 2018/03/25
24.	Aortic Valve Calcification and Subclinical Coronary Atherosclerosis Using Computed Tomography in Japanese Heterozygous Familial Hypercholesterolemia Patients with Gene Mutation 2018/03/25
25.	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK-9) Inhibitors Improve Lipid Profile and Vascular Atherosclerotic Plaque Formation in High-risk Familial Hypercholesterolemia. 2018/03/25
26.	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK-9) Inhibitors Improve Lipid Profile and Vascular Atherosclerotic Plaque Formation in High-risk Familial Hypercholesterolemia. 2018/03/25
27.	The Impact of 18F-fluorodeoxyglucose Uptake on Serial Cardiac Positron Emission Tomography Guided Therapy in Patients with Cardiac Sarcoidosis 2018/03/25
28.	Heterozygous Familial Hypercholesterolemia: Insight into Polygenetic Abnormalities in Japanese Patients 2018/03/24
29.	Sufficient Reduction in FDG Uptake on Serial Cardiac-PET is Associated with Improvement of Cardiac Function in Patients with Cardiac Sarcoidosis 2018/03/24
30.	Assessment of Cardiovascular Atherosclerosis of Heterozygous Familial Hypercholesterolemia (hFH) Using 320-detector Row Coronary CT 2018/03/23
31.	Detection of Myocardial Fibrosis in Cardiomyopathy Using High-temporal Tagging-MRI: Comparison with Feature-tracking MRI 2018/03/23
32.	The Strict Management of Low-Density Lipoprotein Cholesterol in Heterozygous Familial Hypercholesterolemia for the Secondary Prevention of Cardiovascular Disease 2018/03/23
33.	Underdiagnosis and Non-treatment of Heterozygous Familial Hypercholesterolemia in Association with Cardiovascular Disease 2018/03/23
34.	Is Disease Activity of Cardiac Sarcoidosis Suppressed During Maintenance Dose Period of Corticosteroid Therapy? Evaluation by FDG-PET 2018/03/12
35.	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK-9)Inhibitors Improve Lipid Profile and Vascular Atherosclerotic Plaque Formation in High-Risk Familial Hypercholesterolemia 2018/03/11
36.	Polygenetic Abnormalities in Japanese Patients With Heterozygous Familial Hypercholesterolemia 2018/03/10
37.	Insight into Polygenetic Abnormalities in Japanese Heterozygous Familial Hypercholesterolemia 2018/01/06
38.	Underdiagnosis and Undertreatment of Heterozygous Familial Hypercholesterolemia in Association With Cardiovascular Disease 2017/11/14
39.	Aortic valve calcification and coronary plaque morphology in Japanese heterozygous familial hypercholestestreolemia patients with gene mutation 2017/11/11
40.	Gender Difference of Atherosclerotic Development in Heterozygous Familial Hypercholesterelemia 2017/09/16
41.	Under-diagnosis and Under-treatment of Heterozygous Familial Hypercholesterelaemia in Patients with Cardiovascular Diseases 2017/08/29
42.	Polygenetic Abnormalities in Japanese Patients with Heterozygous Familial Hypercholesterolemia 2017/07/07
43.	Assessment of cardiovascular atherosclerosis of heterozygous familial hypercholesterolemia (hFH) using 320-slice coronary CT 2017/07/06
44.	Myocardial fibrosis on cardiac magnetic resonance T1 imaging associates with adverse cardiac event in non-ischemic cardiomyopathy 2017/06/02
45.	Underdiagnosis and Under Treatment of Heterozygous Familial Hypercholesterelemia in Cardiovascular Diseases 2017/03/19
46.	Geometric Dysfunction and Myocardial Fibrosis in Cardiomyopathy: Demonstration by 3T High-temporal Tagged CMR 2017/03/18
47.	The prevalence of polygenetic abnormality in heterozygous familial hypercholesterolemia 2017/03/18
48.	Diagnostic value of transluminal attenuation gradient in coronary computed tomographic imaging for the evaluation of functionally coronary stenosis 2016/08/30
49.	Heterozygous Familial Hypercholesterelemia with Cardiovascular Diseases 2016/07/15
50.	Waist Circumference Predicts Abnormal Left Ventricular Relaxation in Men: Data Obtained through Thorough Physical Examinations in Healthy Subjects 2013/03/09
51.	Aortic stiffness estimated by cardiovascular magnetic resonance correlates with clinical events in patients with hypertrophic cardiomyopathy. 2011/08/28
52.	Aortic Stiffness Estimated by MRI is Increased in Patients with Systemic Sclerosis in the Abisence of Apparent Cardiovascular Involvement 2011/08
53.	What are the High Risk Factors for Coronary Atherosclerosis,Adipocytekines,Epicardilal Fat,Visceral Fat,or the Other Metabolic Factors? 2011/08
54.	1071-Evaluation of plaque Morphology and Epicardial Fat by 64-Slice Multi-Detector Computed Tomography(MDCT)Associated With Glucose Levels. 2010/11
55.	Evaluation of Plaque Morphology and Pericardial Fat by 64-slice Multi-detector Computed Tomography(MDCT) Associated with Glucose Levels 2010/03
56.	The optimum timing of Bentall’s operation for the patients with Marfan syndrome who have annulo aortic ectasia: Discussion based on our experiences. 2000/11
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■ Education

1.		Faculty of Medicine, Tokyo Women's Medical University, Graduated,
2.		〔Doctoral course〕, Faculty of Medicine, Tokyo Women's Medical University, Completed,