Faculty Information - TAKAHASHI Hironobu

■ Books

1.	Chapter contribution	Intelligent Surfaces for Cell Sheet Engineering, Principles of Regenerative Medicine 2019/08
2.	Chapter contribution	Sociocytology Illuminated by Reconstructing Functional Tissue with Cell Sheet Based Technology, Hyper Bio Assembler for 3D Cellular Systems 2015/07
3.	Chapter contribution	Chapter 23. Intelligent surfaces for cell and tissue delivery, Smart materials for drug delivery 2013/06

■ Published papers

1.	Original article	Nutrient rescue of early maturing and deteriorating satellite cell-derived engineered muscle tissue. 2023/12/23
2.	Original article	Repeated and long-term cryopreservation of primary bovine myogenic cells to maintain quality in biomimetic cultured meat 2023/02/24
3.	Original article	Engineered Human Muscle Tissue from Multilayered Aligned Myofiber Sheets for Studies of Muscle Physiology and Predicting Drug Response. 2023/02
4.	Original article	Development of serum-free and grain-derived-nutrient-free medium using microalga-derived nutrients and mammalian cell-secreted growth factors for sustainable cultured meat production 2023/01/10
5.	Original article	Production of scaffold-free cell-based meat using cell sheet technology. 2022/09
6.	Original article	Contraction Control of Aligned Myofiber Sheet Tissue by Parallel Oriented Induced Pluripotent Stem Cell-Derived Neurons. 2022/08
7.	Original article	In Vitro Tissue Reconstruction Using Decellularized Pericardium Cultured with Cells for Ligament Regeneration 2022/06/10
8.	Original article	Harvest of quality-controlled bovine myogenic cells and biomimetic bovine muscle tissue engineering for sustainable meat production. 2022/06
9.	Original article	Proliferation and differentiation of primary bovine myoblasts using Chlorella vulgaris extract for sustainable production of cultured meat. 2022/03/30
10.	Original article	Simulated microgravity accelerates aging of human skeletal muscle myoblasts at the single cell level 2021/11/12
11.	Original article	Terminal cationization of poly(N-isopropylacrylamide) brush surfaces facilitates efficient thermoresponsive control of cell adhesion and detachment. 2021/06
12.	Original article	Enhanced mechanical properties and cell separation with thermal control of PIPAAm-brushed polymer-blend microfibers. 2020/07
13.	Review article	Thermally-triggered fabrication of cell sheets for tissue engineering and regenerative medicine. 2019/01
14.	Original article	Engineered human contractile myofiber sheets as a platform for studies of skeletal muscle physiology 2018/09
15.	Original article	Human neural tissue construct fabrication based on scaffold-free tissue engineering 2016/10
16.	Review article	Cell sheet-based tissue engineering for organizing anisotropic tissue constructs produced using microfabricated thermoresponsive substrates 2015/11
17.	Original article	Engineered small diameter vascular grafts by combining cell sheet engineering and electrospinning technology 2015/04
18.	Original article	Anisotropic cellular network formation in engineered muscle tissue through the self-organization of neurons and endothelial cells 2015/02
19.	Original article	The use of anisotropic cell sheets to control orientation during the self-organization of 3D muscle tissue 2013/10
20.	Original article	Terminal-functionality effect of poly(N-isopropylacrylamide) brush surfaces on temperature-controlled cell adhesion/detachment 2013/08
21.	Original article	Modulation of cell adhesion and detachment on thermo-responsive polymeric surfaces through the observation of surface dynamics 2013/02
22.	Original article	Control of the formation of vascular networks in 3D tissue engineered constructs 2013/01
23.	Original article	Effect of the hydrophobic basal layer of thermoresponsive block co-polymer brushes on thermally-induced cell sheet harvest 2012/05
24.	Original article	Terminally functionalized thermoresponsive polymer brushes for simultaneously promoting cell adhesion and cell sheet harvest 2012/01
25.	Original article	Anisotropic cell sheets for constructing three-dimensional tissue with well-organized cell orientation 2011/12
26.	Original article	Micropatternd thermoresponsive polymer brush surfaces for fabricating cell sheets with well-controlled orientational structures 2011/03
27.	Original article	Controlled Chain Length and Graft Density of Thermoresponsive Polymer Brushes for Optimizing Cell Sheet Harvest 2010/08
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■ Academic conference presentation

1.	Fabrication of Quasi-isotropic Layered 3D Tissue by Aligned Human IPS Cell-derived Cardiomyocytes 2023/12/02
2.	Potential application of microalgae in cultured medium for sustainable cultured meat production 2023/10/16
3.	Fibroblast alignment control regulates cardiomyocyte alignment in the bioengineered cardiac tissue 2023/03/12
4.	A novel culture medium for cultured meat production using microalgae-derived nutrients and mammalian cell-secreted growth factors: Development of serum-free and grain-derived nutrient-free medium 2022/12/07
5.	Primary culture of bovine muscle cells and fabrication of aligned muscle tissues for cultured meat production 2022/10/05
6.	Current strategies for structural and physiological maturation of in-vitro engineered human muscle tissues 2021/11/18
7.	Engineering myofiber constructs for studies of skeletal muscle physiology 2019/10/17
8.	Engineering a functional muscle tissue using a fibrin-based gel for tissue modeling 2018/09/11
9.	Functionalization of a human skeletal muscle tissue construct using a fibrin-based gel for tissue modeling 2018/09/07
10.	Effective development of neuromuscular junction in co-culture with hiPS cell-derived motor neurons and oriented engineered muscle tissue 2018/09/06
11.	Cell sheet-based tissue engineering for producing a contractile muscle tissue construct 2017/09/04
12.	Thermally Modulated Cell Separation System using Micro/Nano-Imprinted Substrates Grafted with Thermoresponsive Polymer 2017/06/09
13.	Micro-fabricated thermoresponsive polymer-grafted surface for producing contractile muscle tissue construct 2017/04/19
14.	Production of contractile muscle tissue constructs based on cell sheet tissue engineering 2017/04/06
15.	Production of a contractile muscle tissue construct based on cell sheet technology 2016/09/04
16.	Cell sheet-based tissue engineering for organizing anisotropic muscle tissue constructs produced using microfabricated thermoresponsive materials 2016/05/22
17.	Micropatterned thermoresponsive materials for designing 3D Microstructures in Engineered Tissue Constructs 2015/12/04
18.	Anisotropic Network Formation of Neurons and Endothelial Cells in Engineered Muscle Tissue Construct 2015/04/18
19.	The assessment of aligned murine skeletal muscle cell sheet 2014/11/07
20.	Construction of cell sheet-based 3D tissues with designed cell orientation using anisotropic cell sheets 2014/11
21.	The use of Anisotropic Cell Sheets for Controlling Orientation during the Self-Organization of 3D Tissue Construct 2014/04/18
22.	End-functional Poly(N-isopropylacrylamide) Brush Surfaces for Temperature-controlled Cell Adhesion Property 2013/09/10
23.	End-Functiomality Effect of Poly(N-isopropylacrylamide) Brushes on Surface Properties and Temperature-dependent Cell Adhesion Behavior 2013/09/08
24.	Effects of Terminal-functionality Poly(N-isopropylacrylamide) Brushes on Temperature-controlled Cellular Adhesion/Detachment Behavior 2013/08/29
25.	Anisotropic myoblast sheets that control 3D muscle tissue orientation 2013/06/27
26.	Terminal-Functionality Effect of Thermoresponsive Polymer Brushes on Surface Properties and Temperature-Induced Cell Adhesion Behavior 2013/06/27
27.	Controlled end-functionality of thermoresponsive polymer brushes for regulating thermally induced surface cell adhesion behavior 2013/04/10
28.	Thermoresponsive interfacial nanostrucutre modulates cell adhesion and detachment characters 2012/10/16
29.	Construction of three-dimensional tissue with well-organized cell orientation using anisotropic cell sheets 2012/06
30.	Effect of Hydrophobic Basal Layer in Thermoresponsive Block Copolymer Brush Surfaces on Harvesting Cell Sheets 2012/05
31.	Three-dimensional design of cell orientation in reconstructed tissue using anisotropic cell sheets 2012/03
32.	Micropatterned Thermoresponsive Polymer Brush Surfaces for Preparation of Cell Sheets with Well-defined Alignment 2011/04
33.	Characterization of Temperature Responsive Polymeric Surface Using Atomic Force Microscopy 2011/03/15
34.	Poly(N-isopropylacrylamide)-Based Block Copolymer Brush Surfaces for Temperature-controlled Cell Adhesion/Detachment 2011/03
35.	Preparation of Cell Sheets with Well-defined Alignment Using Micro-patterned Thermoresponsive Polymer Brush Surfaces 2011/03
36.	Micro-patterned thermoresponsive polymer brush surfaces for engineered cell sheet fabrication 2011/02
37.	Surface Property of Temperature-Responsive Polymeric Thin Surface Observed by Atomic Force Microscopy 2010/12
38.	Thermoresponsive Polymer Brushes for Optimizing Cell Sheet Harvest: Precise Control of Chain Length and Graft Density 2010/12
39.	Surface Property of Temperature-Responsive Polymeric Thin Surface Observed by Atomic Force Microscopy 2010/09
40.	Interaction between temperature responsive polymers observed by atomic force microscopy. 2010/05/26
41.	Thermoresponsive Polymer Brush Surfaces for Cell Sheet Harvest: Control of Polymer Length and Graft Density. 2010/05/26
42.	Effect of conformational change of temperature-responsive polymeric surfaces observed by atomic force microscopy 2010/05
43.	Poly(N-isopropylacrylamide) brush surfaces for thermally modulated cell attachment/detachment 2009/05
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■ Research areas

Biomedical engineering, Composite materials and interfaces, Bio chemistry

■ Awards & honors

1.

2012/06

World Biomaterials Congress Poster Award

■ Education

1.

2003/04～2006/03

〔Doctoral course〕, Kyushu University, Completed,