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 Department of Pharmacology
Summary Research grants & projects Published papers
Books Academic conference presentation


Professor：

    Maru Yoshiro 		Associate Professor：
    HIRATSUKA Sachie 		Assistant Professor：
    Fujiko Tsukahara 		Assistant Professor：
    Katsuaki Ieguchi
   Morichika Takita
   出口　敦子
   富田　毅
■ Summary
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■ Research grants & projects
1.  
 Budget amount：\1,610,000  (Principal investigator)
2.    (Grant No.：26440063)
 Budget amount：\1,200,000  (Principal investigator)
3.    (Grant No.：15K06842)
 Budget amount：\1,400,000  (Principal investigator)
4.    (Grant No.：15K14411)
 Budget amount：\1,600,000  (Principal investigator)
5.  
 Budget amount：\2,000,000  (Principal investigator)
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
First authorCorresponding
Author		Co-authorFirst authorCorresponding
Author		Co-author First authorCo-authorFirst authorCo-author PresenterCo-presenterPresenterCo-presenter PresenterCo-presenter
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■ Published papers
Original article
1. James S. Meabon, Katsuaki Ieguchi, Rian De Laat, Dmitry Serbzhinsky, Mark P. Hudson, B. Russel Huber, Jesse C. Wiley,Mark Bothwell：  Intracellular LINGO-1 Negatively Regulates Trk Neurotrophin Receptor Signaling.  Molecular and Cellular Neuroscience  70 ：1-10 , 2016.1   DOI:10.1016/j.mcn.2015.11.002
2. Inada Masaki†, Morichika Takita, Yokoyama Satoshi, Tominari Tsukasa, Matsumoto Chiho, Hirata Michiko, Maru Yoshiro, Maruyama Takayuki, Sugimoto Yukihiko, Narumiya Shu, Uematsu Satoshi, Akira Shizuo, Gillian Murphy, Nagase Hideaki, Miyaura Chisato*：  Direct Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling That Drives Tumor Growth, Angiogenesis, and Metastasis.  Journal of Biological Chemistry  290 ：29781-29793 , 2015.10   DOI:10.1074/jbc.M115.669481 Link
3. Inada Masaki, Takita Morichika, Yokoyama Satoshi, Watanabe Kenta, Tominari Tsukasa, Matsumoto Chiho, Hirata Michiko, Maru Yoshiro, Maruyama Takayuki, Sugimoto Yukihiko, Narumiya Shuh, Uematsu Satoshi, Akira Shizuo, Murphy Gillian, Nagase Hideaki, Miyaura Chisato：  Direct Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling that Drives Tumor Growth, Angiogenesis and Metastasis.  The Journal of biological chemistry  ：DOI（10.1074/jbc.M115.669481） , 2015.10   DOI:10.1074/jbc.M115.669481
4. Meabon JS, De Laat R, Ieguchi K, Wiley JC, Hudson MP, Bothwell M：  LINGO-1 protein interacts with the p75 neurotrophin receptor in intracellular membrane compartments.  The Journal of Biological Chemistry  290 (15) ：9511-9520 , 2015.4   DOI:10.1074/jbc.M114.608018
5. Maru Yoshiro, Tomita Takeshi*, Deguchi Atsuko, Ieguchi Katsuaki, Takita Morichika, Tsukahara Fujiko, Takemura Kazuhiro, Kitao Akio, Gusovsky Fabian：  Drug Targeting Based on a New Concept-Targeting Against TLR4 as an Example.  Endocrine, metabolic & immune disorders drug targets  15 (2) ：83-87 , 2015   DOI:10.2174/187153031502150522123746 Link
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Review article
1. Maru Yoshiro：  The lung metastatic niche.  Journal of molecular medicine (Berlin, Germany)  93 (11) ：1185-1192 , 2015.11   DOI:10.1007/s00109-015-1355-2
2. 富田　毅、丸　義朗：  TLR4/MD-2のタンパク質内因性リガンドと癌転移の分子基盤.  医学のあゆみ  253 (11) ：1099-1103 , 2015.6
3. Ieguchi K：  Eph as a target in inflammation.  Endocrine, Metabolic & Immune Disorders - Drug Targets  15 (2) ：119-128 , 2015.4
4. Ieguchi Katsuaki：  Eph as a target in inflammation.  Endocrine, metabolic & immune disorders drug targets  15 (2) ：119-128 , 2015
5. Maru Yoshiro, Tomita Takeshi, Deguchi Atsuko, Ieguchi Katsuaki, Takita Morichika, Tsukahara Fujiko, Takemura Kazuhiko, Kitao Akio, Fabian Gusovsky：  Anti-inflammatory Treatment for Seemingly Non-inflammatory Disorders.  Endocrine, metabolic & immune disorders drug targets  15 (2) ：83-87 , 2015   DOI:10.2174/187153031502150522123746
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■ Books
1. 平塚佐千枝：  腸血管透過性と転移.  月刊　細胞　2015年 9月号  521-524.  ニュー・サイエンス社,  東京, 日本, 2015.9
2. 富田 毅, 丸 義朗：  【リポ多糖とその受容体のフロンティア】 TLR4/MD-2の蛋白質内因性リガンドと癌転移の分子基盤.  医学のあゆみ  1099-1103.  医歯薬出版(株),  日本, 2015.6
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■ Academic conference presentation
1. 丸義朗： がん転移前肺土壌形成は可逆的か,.  第66回日本薬理学会北部会,  富山, 日本,  2015/09
2. ◎瀧田守親, 丸義朗： マウス骨髄前駆細胞32DにおけるP210BCR-ABL発現による細胞死の誘導と好中球への分化亢進.  第24回日本Cell Death学会学術集会,  大阪、日本,  2015/07
3. ◎新井田素子, 塚原富士子, 山本智子, 須藤則広, 澤田誠, 丸義朗, 柴田亮行： 培養ミクログリアに導入したALS関連変異SOD1遺伝子産物の発現量低下.  第56回日本神経病理学会総会学術研究会,  福岡,  2015/06
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  ＊：Corresponding Author
 †：First Author
◎：Presenter