Faculty Information - Aoka Yoshikazu

Published papers

Academic conference presentation

Research areas

Academic society memberships

Education

Academic & professional experience

（Last updated : 2024-07-10 11:45:01）

Aoka Yoshikazu
Department School of Medicine(Tokyo Women's Medical University Adachi Medical Center), School of Medicine

Position Associate Professor

■ Published papers

1.	Original article	The emboryonic angiogenic factor Del1 accerelates tumor growth by enhancing vascular formation. 2002
2.	Original article	Heterogeneity of Hemodynamic Parameters in Untreated Primary Hypertension, and Individualization of Antihypertensive Therapy Based on Noninvasive Hemodynamic Measurements 2013
3.	Case report	Primary cardiac angiosarcoma treated with carbon-ion radiotherapy 2004
4.	Case report	Accessory mitral valve tissue causing severe left ventricular outflow tract obstruction in an adult 2004
5.	Original article	Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor 1998
6.	Original article	Technetium-99m HYNIC-annexin V: a potential radiopharmaceutical for the in-vivo detection of apoptosis 1999
7.	Original article	Retinoic acid suppresses endothelin-1 gene expression at the transcription level in endothelial cells 2001
8.	Original article	Aldosterone blockade by Spironolactone improves the hypertensive vascular hypertrophy and remodeling in angiotensin II overproducing transgenic mice 2009
9.	Original article	REGN-COV2 antibody cocktail in patients with SAS-CoV-1: Observational study from a single institution in Japan 2022/03/30
10.	Original article	Psychological Effects on Healthcare Workers during the COVID-19 Outbreak: A Single-center Study at a Tertiary Hospital in Tokyo, Japan. 2021/09
11.	Other	Study of the asymptomatic persons' specificity of reverse transcription polymerase chain reaction for the diagnosis of coronavirus disease (COVID-19) 2021/07
12.	Original article	Clinical features of patients positive for SARS-CoV-2 by RT-PCR in a fever clinic for COVID-19; Comparison with negative PCR cases and comparison of the first and second waves. 2021/01
13.	Original article	Delayed enhancement on computed tomography in abdominal aortic aneurysm wall. 2007
14.	Original article	Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes. 2006
15.	Original article	Heparin Regulates Transcription of Endothelin-1 Gene in Endothelial Cells 2005
16.	Original article	Matrix metalloproteinase 2 is suppressed by trapidil, a CD40-CD40 ligand pathway inhibitor, in human abdominal aortic aneurysm wall. 2004
17.	Original article	A 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, cerivastatin, suppresses production of matrix metalloproteinase-9 in human abdominal aortic aneurysm wall. 2002
18.	Original article	An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats. 2002
19.	Original article	Expression of peroxisome proliferator-activated receptor-gamma in vascular smooth muscle cells is upregulated in cystic medial degeneration of annuloaortic ectasia in Marfan syndrome. 2002
20.	Original article	Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis in cystic medial degeneration associated with Marfan's syndrome. 2001
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■ Academic conference presentation

1.	Noninvasive Detection of Subclinical Left Ventricular Dysfunction by Strain Echocardiography in Patients with Marfan Syndrome 2011/03/18
2.	The Age Distribution of High Cardiac Output Hypertension in Untreated Essential Hypertension. 2010/06
3.	Limitation of monotherapy and benefit of impedance cardiography as a guide for a combination therapy in achieving blood pressure control in essential hypertension. 2009/05
4.	Is Beta Blocker Unnecessary for the First Choice of Antihypertensive Agents? Lesson from Non-Invasive Hemodynamic Study Using Impedance Cardiography. 2008/05
5.	Clinical value of non-Invasive Stroke Volume Measurement using Impedance Cardiography for the Assessment of Arterial Stiffness. 2007/06
6.	Hemodynamic alteration by additional use of low dose spironolactone in the management of resistant hypertension. 2007/06
7.	Clinical Features of Painless Aortic Dissection 2005/03
8.	Aldosterone Blockade by Spironolactone Improves the Hypertensive Vascular Remodeling in Angiotensin II Overproducing Transgenic Mice 2004/03
9.	Long-term follow up of the patients with Takayasu arteritis 2003/03
10.	Synergistic upregulation of ABCA1 mRNA by Angiotensin II and oxidized LDL in human peripheral blood monocyte from normocholesteremic healthy volunteers 2002/03
11.	The Distribution of mast cells and vasa vasorum in the wall of aortic aneurysm 2001/03
12.	The optimum timing of Bentall’s operation for the patients with Marfan syndrome who have annulo aortic ectasia: Discussion based on our experiences. 2000/11
13.	The embryonic endothelial marker Del1 is a novel proangiogenic factor. 1998/11
14.	Nitric oxide-cyclic GMP regulates transcription of the Endothelin-1 gene 1994/11
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■ Research areas

General medicine, Cardiovascular medicine (Key Word：general internal medicine, hypertension)

■ Academic society memberships

1.	1991/08～	The Japanese society of internal medicine
2.	2005/09～	The Japanese society of Hypertension
3.	2019/05～	Japan primary care association
4.	2020/06～	The Japanese society of hospital general medicine
5.	1991～2016/09	The Japanese Circulation Society

■ Education

1.	1984/04～1990/03	Faculty of Medicine, Shinshu University, Graduated
2.	1996/03～1997/08	Divsion of Cardiology, Faculty of Medicine, Vanderbilt University, Studying abroad
3.	1997/08～1998/07	Division of Cardiovascular medicine, Faculty of Medicine, Stanford University, Studying abroad
4.	2004/09/17 Degree Acquisition	Tokyo Women's Medical University,

■ Academic & professional experience

2007/08～2011/03

Lecturer