Faculty Information - NAKAYAMA Masamichi

Books

Published papers

Academic conference presentation

Research areas

Education

Rsearch funding number

External Researcher ID

（Last updated : 2025-04-12 11:55:06）

NAKAYAMA Masamichi
Department Graduate School of Medical Science, Graduate School of Medical Science

Position Assistant Professor

■ Books

1.	Chapter contribution	Sociocytology Illuminated by Reconstructing Functional Tissue with Cell Sheet Based Technology, Hyper Bio Assembler for 3D Cellular Systems 2015/07
2.	Chapter contribution	Responsive polymer coatings for smart applications in chromatography, drug delivery systems, and cell sheet engineerin, Intelligent Surfaces in Biotechnology 2012

■ Published papers

1.	Review article	Molecular design of dynamically thermoresponsive biomaterials 2025/03/24
2.	Original article	Visible-light-triggered recovery of biologically intact cells using smart fluoropolymer-nanocoated materials. 2025/03
3.	Original article	Stable preparation of in vivo transplantable periodontal ligament-derived mesenchymal stem cell sheets in thermoresponsive culture dishes with tunable cell detachability 2025/01/13
4.	Original article	Terminal cationization of poly(N-isopropylacrylamide) brush surfaces facilitates efficient thermoresponsive control of cell adhesion and detachment. 2021/06
5.	Review article	Living Radical Polymerization 2021/01/25
6.	Original article	Micropatterned Smart Culture Surfaces via Multi-Step Physical Coating of Functional Block Copolymers for Harvesting Cell Sheets with Controlled Sizes and Shapes. 2020/12
7.	Original article	Water Stable Nanocoatings of Poly(N-isopropylacrylamide)-based Block Copolymers on Culture Insert Membrane for Temperature-Controlled Cell Adhesion 2020/07/17
8.	Original article	Efficient intrahepatic tumor generation by cell sheet transplantation to fabricate orthotopic hepatocarcinoma-bearing model mice for drug testing 2019/05
9.	Review article	Perfusable Tissue-Engineered Neuroblastoma Model for Drug Resistance Study 2018/07
10.	Original article	Controlled aggregation behavior of thermoresponsive polymeric micelles by introducing hydrophilic segments as corona components 2018/06
11.	Original article	Surface sulfonamide modification of poly(N-isopropylacrylamide)-based block copolymer micelles to alter pH and temperature responsive properties for controlled intracellular uptake 2018/06
12.	Original article	Improved In Vivo Subcutaneous Tumor Generation by Cancer Cell Sheet Transplantation 2018/02
13.	Original article	Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma 2017/09
14.	Original article	Transplantation of cancerous cell sheets effectively generates tumour-bearing model mice 2016/10
15.	Original article	Preparation of thermoresponsive nanostructured surfaces for tissue engineering 2016/03
16.	Original article	A Biomimicking Tumor Tissue Model Using Hepatocellula Carcinoma Cell Sheet in a Collagen Sandwich System 2015/12
17.	Original article	Anisotropic cellular network formation in engineered muscle tissue through the self-organization of neurons and endothelial cells 2015/02
18.	Original article	Thermoresponsive Nanostructured Surfaces Generated by the Langmuir-Schaefer Method Are Suitable for Cell Sheet Fabrication 2014/11
19.	Review article	Multi-targeting system with fusion between thermoresponsive carriers and mild hyperthermia: Original Research Article: Thermo-responsive drug delivery from polymeric micelles constructed using block copolymers of poly(N-isopropylacrylamide) and poly(butylmethacrylate) (1999) 2014/09
20.	Review article	Polymeric micelles with stimuli-triggering systems for advanced cancer drug targeting 2014/07
21.	Review article	Temperature-responsive polymeric micelles for optimizing drug targeting to solid tumors 2014/07
22.	Original article	Facile cell sheet manipulation and transplantation by using in situ gelation method 2014/04
23.	Original article	Control of cell adhesion and detachment on Langmuir-Schaefer surface composed of dodecyl-terminated thermo-responsive polymers 2013/12
24.	Original article	The use of anisotropic cell sheets to control orientation during the self-organization of 3D muscle tissue 2013/10
25.	Original article	Terminal-functionality effect of poly(N-isopropylacrylamide) brush surfaces on temperature-controlled cell adhesion/detachment 2013/08
26.	Original article	Modulation of cell adhesion and detachment on thermo-responsive polymeric surfaces through the observation of surface dynamics 2013/02
27.	Original article	Synthesis of terminal-functionalized thermoresponsive diblock copolymers using biodegradable macro-RAFT agents 2013/02
28.	Original article	pH-induced phase transition control of thermoresponsive nano-micelles possessing outermost surface sulfonamide moieties 2012/11
29.	Original article	Thermoresponsive Poly(N-isopropylacrylamide)-Based Block Copolymer Coating for Optimizing Cell Sheet Fabrication 2012/06
30.	Original article	Effect of the hydrophobic basal layer of thermoresponsive block co-polymer brushes on thermally-induced cell sheet harvest 2012/05
31.	Original article	Terminally functionalized thermoresponsive polymer brushes for simultaneously promoting cell adhesion and cell sheet harvest 2012/01
32.	Original article	The non-invasive cell surface modification of hepatocytes with PEG-lipid derivatives. 2012/01
33.	Original article	Anisotropic cell sheets for constructing three-dimensional tissue with well-organized cell orientation 2011/12
34.	Original article	Effect of block compositions of amphiphilic block copolymers on the physicochemical properties of polymeric micelles 2011/08
35.	Original article	Micropatternd thermoresponsive polymer brush surfaces for fabricating cell sheets with well-controlled orientational structures 2011/03
36.	Original article	Multi-targeting cancer chemotherapy using temperature-responsive drug carrier systems 2011/03
37.	Review article	Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering 2010/11
38.	Original article	Controlled Chain Length and Graft Density of Thermoresponsive Polymer Brushes for Optimizing Cell Sheet Harvest 2010/08
39.	Original article	Thermally Controlled Intracellular Uptake System of Polymeric Micelles Possessing Poly(N-isopropylacrylamide)-Based Outer Coronas 2010/05
40.	Original article	Temperature-Induced Intracellular Uptake of Thermoresponsive Polymeric Micelles 2009/04
41.	Original article	Molecular design of outermost surface functionalized thermoresponsive polymeric micelles with biodegradable cores 2008/11
42.	Original article	Unique thermoresponsive polymeric micelle behavior via cooperative polymer corona phase transitions 2008/01
43.	Original article	Thermal modulation of intracellular drug distribution using thermoresponsive polymeric micelles 2007/11
44.	Original article	Molecular design of biodegradable polymeric micelles for temperature-responsive drug release 2006/07
45.	Review article	Intelligent polymeric micelles for targeted drug delivery 2006/01
46.	Original article	Polymer terminal group effects on properties of thermoresponsive polymeric micelles with controlled outer-shell chain lengths 2005/06
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■ Academic conference presentation

1.	Micropatterned thermoresponsive surfaces via physical block copolymer coatings for fabricating cell sheets with designed morphological structures （ポスター掲示，一般） 2022/01/10
2.	Micropatterned smart surfaces via physical polymer coatings for fabricating cell sheets with on-demand morphological structures （ポスター掲示，一般） 2021/11/29
3.	Stimuli-responsive polymer nanocoatings on culture substrates for smart cell adhesion control （口頭，特別講演・招待講演など） 2020/11/27
4.	Transplantation of Sheet-like Cancer Cell tissues for Orthotopic Tumor-bearing animal models （ポスター掲示，一般） 2020/06/29
5.	Controlled structure of cell sheets using micropatterned thermoresponsive surfaces prepared by polymer stamping method （ポスター掲示，一般） 2019/09/12
6.	Smart fluoropolymer-coated surface for visible light-triggered cell recovery （口頭，一般） 2017/08/23
7.	Fabrication of patterned thermoresponsive surface by polymer printing method and analysis of cell adhesion behavior （ポスター掲示，一般） 2017/05/30
8.	Temperature-responsive polymer coating for harvesting biologically intact cell sheets （ポスター掲示，一般） 2017/03/07
9.	Smart fluoropolymer-coated biointerface for visible-light induced cell detachment system （ポスター掲示，一般） 2017/03/06
10.	Visible light-triggered cell detachment system using smart fluoropolymer coated surface （口頭，一般） 2016/12/14
11.	Visible light-triggered cell recovery system from intelligent fluoropolymer coated surface （ポスター掲示，一般） 2016/11/28
12.	Thermoresponsive polymeric materials for smart drug delivery applications （口頭，特別講演・招待講演など） 2016/10/16
13.	Cell sheet-based tissue engineering for organizing anisotropic muscle tissue constructs produced using microfabricated thermoresponsive materials （口頭，一般） 2016/05/22
14.	Visible-light induced cell detachment system using smart fluoropolymer-coated surface （口頭，一般） 2016/05/18
15.	Light-sensitive Fluoropolymer Coated Surfaces for Smart Cell Recovery System （口頭，特別講演・招待講演など） 2016/03/05
16.	Thermoresponsive Nano-polymeric Materials toward Smart Drug Delivery Applications （口頭，シンポジウム・ワークショップパネル（その他）） 2015/09/16
17.	Photo-responsive Fluoropolymer Coated Surface for Cell Adhesion Control （ポスター掲示，一般） 2015/08/31
18.	Effective Fabrication of Tumor-bearing Animal Models by Cancer Cell Sheet Transplantation （ポスター掲示，一般） 2015/07/27
19.	FABRICATION OF ORTHOTOPIC TUMOR-BEARING MICE BY HEPATOCARCINOMA CELL SHEET TRANSPLANTATION （ポスター掲示，一般） 2015/06/15
20.	Visible-light induced cell recovery system using intelligent fluoropolymer-coated surface （ポスター掲示，一般） 2015/06/15
21.	Stimuli-Responsive Polymer Coated Surfaces for Smart Cell Manipulation （口頭，シンポジウム・ワークショップパネル（その他）） 2015/05/10
22.	Anisotropic Network Formation of Neurons and Endothelial Cells in Engineered Muscle Tissue Construct （口頭，一般） 2015/04/18
23.	Light-sensitive Fluoropolymer Coated Surface for Control of Cell Adhesion Behavior （ポスター掲示，一般） 2015/04/16
24.	Light-responsive fluoropolymer coated surface for dynamic control of cell adhesion （ポスター掲示，一般） 2015/03/09
25.	Construction of cell sheet-based 3D tissues with designed cell orientation using anisotropic cell sheets （口頭，シンポジウム・ワークショップパネル（指名）） 2014/11
26.	Thermo-Responsive Nano-Structured Surface Modulates Cell Adhesion and Detachment （ポスター掲示，一般） 2014/09/01
27.	Nano-scale Surface Coating of Poly(N-isopropylacrylamide)-based Block Copolymers for Cell Sheet Harvest （口頭，一般） 2014/08/26
28.	End-functional Poly(N-isopropylacrylamide) Brushes for Efficiently Promoting Cell Adhesion and Detachment （ポスター掲示，一般） 2014/04/18
29.	The use of Anisotropic Cell Sheets for Controlling Orientation during the Self-Organization of 3D Tissue Construct （ポスター掲示，一般） 2014/04/18
30.	Control of Cell Adhesion and Detachment on Thermo-Responsive Block Copolymer Langmuir Films （ポスター掲示，一般） 2013/12/03
31.	End-functional Poly(N-isopropylacrylamide) Brush Surfaces for Temperature-controlled Cell Adhesion Property （ポスター掲示，一般） 2013/09/10
32.	End-Functiomality Effect of Poly(N-isopropylacrylamide) Brushes on Surface Properties and Temperature-dependent Cell Adhesion Behavior （ポスター掲示，一般） 2013/09/08
33.	Effects of Terminal-functionality Poly(N-isopropylacrylamide) Brushes on Temperature-controlled Cellular Adhesion/Detachment Behavior （ポスター掲示，一般） 2013/08/29
34.	Nano-scale Surface Coating of Thermoresponsive Block Copolymers for Thermally Regulating Cell Adhesion/Detachment Behavior （ポスター掲示，一般） 2013/07/23
35.	Ultrathin Thermoresponsive Polymer-Coated Surfaces for Temperature-Regulated Cell Adhesion/Detachment （ポスター掲示，一般） 2013/06/28
36.	Anisotropic myoblast sheets that control 3D muscle tissue orientation （口頭，一般） 2013/06/27
37.	Control of Cell Adhesion and Detachment on Thermo-Responsive Langmuir Films （ポスター掲示，一般） 2013/06/27
38.	Terminal-Functionality Effect of Thermoresponsive Polymer Brushes on Surface Properties and Temperature-Induced Cell Adhesion Behavior （ポスター掲示，一般） 2013/06/27
39.	Control of Cell Adhesion and Detachment on Thermo-responsive Block Copolymer Langmuir films （口頭，一般） 2013/05/31
40.	Ultrathin Surface Coating of Thermoresponsive Block Copolymers for Fabricating Cell Sheets （口頭，一般） 2013/04/13
41.	Controlled end-functionality of thermoresponsive polymer brushes for regulating thermally induced surface cell adhesion behavior （口頭，一般） 2013/04/10
42.	Control of cell adhesion and detachment on thermo-responsive Langmuir films （ポスター掲示，一般） 2013/03/19
43.	Nano-scale surface coating of thermoresponsive polymers for temperature-controlled cell adhesion/detachment （ポスター掲示，一般） 2013/02/04
44.	Thermoresponsive interfacial nanostrucutre modulates cell adhesion and detachment characters （ポスター掲示，一般） 2012/10/16
45.	Fabrication of tumor-bearing model mice using cell sheet engineering （ポスター掲示，一般） 2012/09/06
46.	Thermoresponsive block copolymer-coated surfaces for optimizing cell sheet fabrication （ポスター掲示，一般） 2012/09/05
47.	Thermoresponsive block copolymer-based biomaterials for controlling cellular interactions （ポスター掲示，一般） 2012/07/17
48.	Construction of three-dimensional tissue with well-organized cell orientation using anisotropic cell sheets （ポスター掲示，一般） 2012/06
49.	Effect of Hydrophobic Basal Layer in Thermoresponsive Block Copolymer Brush Surfaces on Harvesting Cell Sheets （ポスター掲示，一般） 2012/05
50.	Three-dimensional design of cell orientation in reconstructed tissue using anisotropic cell sheets （ポスター掲示，シンポジウム・ワークショップパネル（その他）） 2012/03
51.	Smart Coating of Poly(N-isopropylacrylamide)-Based Block Copolymers for Cell Sheet Harvest （一般） 2011/04/13
52.	Micropatterned Thermoresponsive Polymer Brush Surfaces for Preparation of Cell Sheets with Well-defined Alignment （ポスター掲示，一般） 2011/04
53.	Characterization of Temperature Responsive Polymeric Surface Using Atomic Force Microscopy （ポスター掲示，一般） 2011/03/15
54.	Thermoresponsive diblock copolymer-coated surfaces for temperature-controlled cell adherent/detachment （ポスター掲示，一般） 2011/03/15
55.	Poly(N-isopropylacrylamide)-Based Block Copolymer Brush Surfaces for Temperature-controlled Cell Adhesion/Detachment （ポスター掲示，一般） 2011/03
56.	Preparation of Cell Sheets with Well-defined Alignment Using Micro-patterned Thermoresponsive Polymer Brush Surfaces （ポスター掲示，一般） 2011/03
57.	Micro-patterned thermoresponsive polymer brush surfaces for engineered cell sheet fabrication （ポスター掲示，シンポジウム・ワークショップパネル（その他）） 2011/02
58.	Outermost surface functionalized thermoresponsive polymeric micelles for biomedical applications （ポスター掲示，一般） 2010/12/17
59.	Surface Property of Temperature-Responsive Polymeric Thin Surface Observed by Atomic Force Microscopy （ポスター掲示，一般） 2010/12
60.	Thermoresponsive Polymer Brushes for Optimizing Cell Sheet Harvest: Precise Control of Chain Length and Graft Density （口頭，一般） 2010/12
61.	Surface Property of Temperature-Responsive Polymeric Thin Surface Observed by Atomic Force Microscopy （ポスター掲示，一般） 2010/09
62.	Interaction between temperature responsive polymers observed by atomic force microscopy. （口頭，一般） 2010/05/26
63.	Thermoresponsive Polymer Brush Surfaces for Cell Sheet Harvest: Control of Polymer Length and Graft Density. （口頭，一般） 2010/05/26
64.	Temperature-modulated intracellular uptake system of thermoresponsive polymeric micelles. （ポスター掲示，一般） 2010/05/10
65.	Thermoresponsive polymeric micelles for biomedical application （口頭，特別講演・招待講演など） 2010/05/10
66.	Effect of conformational change of temperature-responsive polymeric surfaces observed by atomic force microscopy （ポスター掲示，一般） 2010/05
67.	Novel Design of Outermost Surface Functionalized Thermoresponsive Polymeric Micelles 2009/09/10
68.	Novel Design of pH- and Temperature-Responsive Nano Micelles for Intelligent Drug Carrier System （ポスター掲示，一般） 2009/07
69.	Outermost Surface Sulfonamide-Functionalized Thermoresponsive Nano-Micelles as Multi-Stimuli Responsive Drug Carrier System （口頭，一般） 2009/05/22
70.	Effect of the Block Lengths of Amphiphilic Block Copolymers on Self-Assembly and Hydrophobic Anticancer Drug Incorporation （ポスター掲示，一般） 2009/05
71.	Poly(N-isopropylacrylamide) brush surfaces for thermally modulated cell attachment/detachment （ポスター掲示，シンポジウム・ワークショップパネル（その他）） 2009/05
72.	Thermoresponsive Polymeric Micelles Comprising End-Functional Diblock Copolymers （口頭，特別講演・招待講演など） 2009/04/20
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■ Research areas

Biomedical engineering, Nanomaterials, Nanomaterials, Polymer chemistry

■ Education

〔Doctoral course〕〔Doctorial Course〕, Graduate School, Division of Engineering, Kyushu University, Completed,

■ Rsearch funding number

00338980

■ External Researcher ID

orcID

0000-0002-5484-583X