Faculty Information - Komoike Yuuta

（Last updated : 2024-06-28 15:54:36）

Komoike Yuuta
Department School of Medicine, School of Medicine Department of Hygiene and Public Health, Division of Environmental and Occupational Medicine

Position Associate Professor

■ Published papers

1.	Original article	Developmental adverse effects of trace amounts of lead: evaluation using zebrafish model 2022/09/21
2.	Original article	Intake of acrylamide at the dietary relevant concentration causes splenic toxicity in adult zebrafish 2020/10
3.	Original article	In vitro and in vivo studies of oxidative stress response against acrylamide toxicity in zebrafish 2019/03
4.	Original article	Endoplasmic reticulum stress-mediated neuronal apoptosis by acrylamide exposure 2016/11
5.	Original article	DNA Damage Response in Proliferating Müller Glia in the Mammalian Retina 2016/03
6.	Review article	Experimental evidence shows salubrinal, an eIF2α dephosphorylation inhibitor, reduces xenotoxicant-induced cellular damage 2015/07
7.	Original article	Single nucleotide variations in CLCN6 identified in patients with benign partial epilepsies in infancy and/or febrile seizures. 2015
8.	Original article	Novel compound heterozygous mutations of POLR3A revealed by whole-exome sequencing in a patient with hypomyelination. 2014
9.	Original article	Exposure to tributyltin induces endoplasmic reticulum stress and the unfolded protein response in zebrafish 2013/08
10.	Original article	Potential teratogenicity of methimazole: Exposure of zebrafish embryos to methimazole causes similar developmental anomalies to human methimazole embryopathy 2013/06
11.	Original article	Reduced PLP1 expression in induced pluripotent stem cells derived from a Pelizaeus-Merzbacher disease patient with a partial PLP1 duplication. 2012/09
12.	Original article	Characterization of a novel KRAS mutation identified in Noonan Syndrome 2012/03
13.	Original article	Effects of salubrinal on cadmium-induced apoptosis in HK-2 human renal proximal tubular cells 2012/01
14.	Original article	Myogenic differentiation in atrium-derived adult caridac pluripotent cells and the transcriptional regulation of 2-TFs (GATA4 and myogenin) on ANP promoter 2010/05
15.	Original article	zebrafish gene knockdowns imply roles for human YWHAG in infantile spasms and cardiomegaly. 2010/04
16.	Original article	A functional analysis of GABARAP on 17p13.1 by knockdown zebrafish. 2010/03
17.	Original article	TULIP1 (RALGAPA1) haploinsufficiency with brain development delay 2009/12
18.	Original article	Germline gain-of-function mutations in RAF1 cause Noonan syndrome 2007/08
19.	Original article	Adaptive changes in TEF-1 gene expression during cold acclimation in the medaka. 2006/10
20.	Original article	Cellular responses of the ciliate, Tetrahymena thermophila, to far infrared irradiation. 2006/09
21.	Original article	Identification of a nuclear localization signal in mouse polycomb protein, M33. 2006/09
22.	Original article	Zebrafish Polycomb group gene ph2alpha is required for epiboly and tailbud formation acting downstream of FGF signaling. 2005/03
23.	Original article	Cloning of cDNAs encoding the three pituitary glycoprotein hormone beta subunit precursor molecules in the Japanese toad, Bufo japonicus. 2003/06
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■ Academic conference presentation

1.	Effects of long-term acrylamide-contaminated food intake at the dietary relevant concentration in zebrafish. 2024/03/09
2.	Evaluation of developmental adverse effects of trace amount of lead using zebrafish model. 2023/07/29
3.	Adverse developmental effects of trace amounts of lead: Evaluation using zebrafish model 2023/03/04
4.	Effects of trace amount of Pb on zebrafish embryonic development 2022/03/21
5.	Application of zebrafish model 2020/08/18
6.	Protective effect of oxidative stress response against acrylamide toxicity 2019/02/02
7.	Investigation of cellular response pathways involved in the expression of acrylamide toxicity 2018/03/24
8.	Cell cycle reentry and DNA damage response of Müller glia after retinal injury 2016/09/26
9.	Single nucleotide variation in CLCN6 identified in patients with benign partial epilepsies in infancy and/or febrile seizures. 2016/04/03
10.	Utilization of ICT in the support program for female students in choosing science courses -Future of health-care depends on your activity II- 2015/03/26
11.	Tributyltin induces endoplasmic reticulum stress in experimental model teleost,zebrafish 2014/10/18
12.	Investigation of the teratogenicity of methimazole using zebrafish 2014/07/27
13.	Involvement of endoplasmic reticulum stress response in neurotoxicity of acrylamide 2014/05/27
14.	cell cycle reentry and DNA damage response of Müller glia after retinal injury 2014/03/29
15.	Study on the possible teratogenicity of methimazole: Morphological similarities between methimazole embryopathy and anomalies in zebrafish embryos exposed to methimazole. 2013/07/21
16.	Analysis of endoplasmic reticulum stress response in tributyltin-exposed zebrafish 2013/03/26
17.	Cadmium induces ER stress and apoptosis in renal proximal tubular cells: protection by salubrinal 2012/07/20
18.	A novel gain-of-function Kras mutation identified in Noonan Syndrome, which causes maldevelopment of the heart in zebrafish 2009/09
19.	Comprehensive mutation analysis in Noonan syndrome and functional characterization of a novel Kras mutation 2009/08
20.	Characterization of a novel Kras mutaion identified in Noonan Syndrome 2009/05
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■ Research areas

Radiation influence

■ Education

1.	2001/04～2005/03	〔Doctoral course〕 Major in Bioscience and Biomedical Engineering, Graduate School of Science and Engineering, Waseda University, Completed, PhD
2.	1999/04～2001/03	〔Master degree program〕 Major in Pure and Applied Physics, Graduate School of Science and Engineering, Waseda University, Completed
3.	1995/04～1999/03	Department of Biology, School of Education, Waseda University, Graduated

■ Academic & professional experience

1.	2018/10～2020/06	Lecturer
2.	2016/05～2018/09	Lecturer
3.	2010/04～2016/05	Assistant Professor
4.	2007/04～2010/03	Tokyo Women's Medical University International Research and Educational Institute for Integrated Medical Sciences Assistant Professor
5.	2004/09～2007/03	Research Assistant

■ Rsearch funding number

70386556