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 Department of Pathology, Division of Pathological Neuroscience
Summary Research grants & projects Published papers
Books Academic conference presentation


Professor:

   Shibata Noriyuki
   Sawada Tatsuo
   Watabe Kazuhiko
Assistant Professor:
   Niida Motoko
Assistant Professor:
   Katou Youichirou
   Masui Kenta
■ Summary
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■ Research grants & projects
1.    (Grant No.:15H04844)
 Budget amount:\2,600,000  (Co-investigator)
2.    (Grant No.:15K06763)
 Budget amount:\4,000,000  (Principal investigator)
3.    (Grant No.:15K19067)
 Budget amount:\3,100,000  (Principal investigator)
4.    (Grant No.:S1201009)
 Budget amount:\500,000  (Co-investigator)
5.    (Grant No.:2823)
 Budget amount:\22,000  (Principal investigator)
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
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■ Published papers
Original article
1. Hashimoto H, Kurata A, Fujiwara M, Hara K, Matsumoto J, Kusakabe M, Tachibana K, Nashiro T, Terado Y, Akahane M, Usui K, Suzuki Y, Kondo H, Kamma H, Kuroda M, Horiuchi H:  Solitary pulmonary capillary hemangioma of adult cases: Clinicopathologic characteristics as an unrecognized entity.  The American journal of surgical pathology  40 (10) :1380-9 , 2016.10   DOI:10.1097/PAS.0000000000000708
2. Masui K, Cavenee WK, Mischel PS:  Cancer metabolism as a central driving force of glioma pathogenesis.  Brain Tumor Pathology  33 :161-168 , 2016
3. Wei W, Shin YS, Xue M, Matsutani T, Masui K, Yang H, Ikegami S, Gu Y, Herrmann K, Johnson D, Ding X, Hwang K, Kim J, Zhou J, Su Y, Li X, Bonetti B, Chopra R, James CD, Cavenee WK, Cloughesy TF, Mischel PS, Heath JR, Gini B:  Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma.  Cancer cell  29 :563-573 , 2016
4. Villa GR, Hulce JJ, Zanca C, Bi J, Ikegami S, Cahill GL, Gu Y, Lum KM, Masui K, Yang H, Rong X, Hong C, Turner KM, Liu F, Hon GC, Jenkins D, Martini M, Armando AM, Quehenberger O, Cloughesy TF, Furnari FB, Cavenee WK, Tontonoz P, Gahman TC, Shiau AK, Cravatt BF, Mischel PS:  An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers.  Cancer cell  30 :683-693 , 2016
Review article
1. 増井憲太, 小森隆司:  脳腫瘍学-基礎研究と臨床研究の進歩- Ⅲ. 脳腫瘍の分子生物学と発生機序 分子生物学.  日本臨床  74 (増刊号7) :137-142 , 2016.9
2. 増井憲太, 小森隆司:  放射線診断専門医に必要な脳腫瘍病理.  画像診断  36 (13) :1235-1244 , 2016
3. Masui K, Shibata N, Cavenee WK, Mischel PS:  mTORC2 activity in brain cancer:extracellular nutrients are required to maintain oncogenic signaling.  BioEssays : news and reviews in molecular, cellular and developmental biology  38 :839-844 , 2016
Case report
1. Hashimoto H, Yanagiya M, Kusakabe M, Kurata A, Ohara S, Suzuki Y, Matsumoto J, Horiuchi H:  Atherosclerosis of aberrant arteries from the left gastric artery into the right intralobar pulmonary sequestration complicated by mycobacterial epithelioid cell granuloma.  Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology  26 :4-6 , 2017.1   DOI:10.1016/j.carpath.2016.09.007
2. YAMAMOTO Tomoko*, HIROI Atuko, ITAGAKI Hiroko, KATO Yoichiro, IIZUKA Bunei, ITABASHI Michio, SHIBATA Noriyuki, NAGASHIMA Yoji.:  Well-differentiated adenocarcinoma associated with ulcerative colitis.  SAGE Open Medical Case Reports  5 :1-7 , 2017.1   DOI:10.1177/2050313X17692902. Link
3. Umahara Takahiko*, Uchihara Toshiki, Shibata Noriyuki, Nakamura Ayako, Hanyu Haruo:  14-3-3 eta isoform colocalizes TDP-43 on the coarse granules in the anterior horn cells of patients with sporadic amyotrophic lateral sclerosis.  Brain research  1646 :132-138 , 2016.5   DOI://dx.doi.org/10.1016/j.brainres.2016.05.051
4. Hashimoto H, Hara K, Matsumoto J, Nashiro T, Nagano M, Kusakabe M, Kurata A, Kuroda M, Suzuki Y, Horiuchi H:  Necrotizing arteritis occurring in an intralobar pulmonary sequestration of a patient without systemic vasculitis syndrome.  Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology  25 (3) :200-2 , 2016.5   DOI:10.1016/j.carpath.2016.01.005
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■ Books
1. Masui Kenta, Harachi Mio, Paul S. Mischel, Yamamoto Tomoko, Shibata Noriyuki:  Molecular Targeting of Brain Tumors.  Frontiers in CNS Drug Discovery  3-40.  Bentham Science Publishers,  United Arab Emirates, 2017.3
2. 柴田亮行, 北川一夫, 川俣貴一:  [4]脳静脈疾患の病理.  脳静脈エッセンス 脳静脈の歩き方  43-59.  中外医学社,  東京, 2016.10
3. 増井憲太, 小森隆司:  2. 病理・遺伝学的グリオーマ分類.  脳神経外科 診療プラクティス 7 グリオーマ治療のDecision Making  253-256.  文光堂,  東京, 2016.5
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■ Academic conference presentation
1. ◎原地美緒, 増井憲太, 柴田亮行: EGFR-mTORC1 経路ははがんのエピジェネティクスを制御する.  第11回臨床ストレス応答学会大会,  宇部,  2016/11
2. ◎Sawada Tatsuo: Intraoperative cytology for CNS tumors in new era.  The 15th Korea-Japan Joint Meeting for Diagnostic Cytopathology,  jeju-do, Korea,  2016/10
3. ◎Masui Kenta: MTORC2 promotes histone acetylation through metabolic reprogramming in glioblastoma.  13th Asian Society for Neuro-Oncology (ASNO) Meeting / 9th COGNO Annual Scientific Meeting,  sydney, Australia,  2016/09
4. ◎Sawada Tatsuo, Yamamoto Tomoko, Nagashima Yoji, Hirai Yasuo, Shibata Noriyuki: Intraoperative cytology for ovarian tumor.  The 19th International Congress of Cytology,  Yokohama,  2016/05
5. ◎長嶋洋治, 廣井敦子, 板垣裕子, 鬼塚裕美, 澤田杏理, 山本智子, 近藤恒徳, 森田賢, 澤田達男: 腎腫瘍針生検の病理診断:ガイドラインの作成.  第105回日本病理学会総会,  仙台,  2016/05
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