教員情報 - 時田　大輔

学術雑誌

学会発表

学歴

（最終更新日：2022-02-24 17:08:10）

  トキタ　ダイスケ   TOKITA Daisuke
  時田　大輔
   所属   医学部医学科（東京女子医科大学病院）  研究推進センター

職種教授

■ 著書

部分執筆　

東京女子医科大学における二次腎移植の臨床的検討「第43回日本臨床腎移植学会記録集　腎移植症例集2011」 2010

■ 学術雑誌

1.	原著	Role of fractalkine-CX3CR1 axis in acute rejection of mouse heart allografts subjected to ischemia reperfusion injury 2022/02/01
2.	原著	Nitrite reduces acute lung injury and improves survival in a rat lung transplantation model. 2012/11
3.	原著	Comparison of the acute rejection incidence rate in spousal donor transplantation before and after anti-CD20 antibody (rituximab) protocol as desensitization therapy 2011/02
4.	原著	New-onset diabetes after transplantation in tacrolimus-treated, living kidney transplantation: long-term impact and utility of the pre-transplant OGTT. 2010
5.	原著	後腹膜鏡下ドナー腎摘出術における複数動脈症例の検討 2010
6.	原著	NOD2 ligation subverts IFN-alpha production by liver plasmacytoid dendritic cells and inhibits their T cell allostimulatory activity via B7-H1 up-regulation. 2009/12
7.	総説	Dendritic cell immunobiology in relation to liver transplant outcome. 2009/06
8.	原著	Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression. 2009/05
9.	原著	Poor allostimulatory function of liver plasmacytoid DC is associated with pro-apoptotic activity, dependent on regulatory T cells. 2008/12
10.	原著	Inhibition of Kupffer cell-mediated early proinflammatory response with carbon monoxide in transplant-induced hepatic ischemia/reperfusion injury in rats. 2008/11
11.	原著	Sphingosine 1-phosphate receptor agonism impairs skin dendritic cell migration and homing to secondary lymphoid tissue: association with prolonged allograft survival. 2008/11
12.	原著	Suppressive efficacy and proliferative capacity of human regulatory T cells in allogeneic and xenogeneic responses. 2008/11
13.	原著	High PD-L1/CD86 ratio on plasmacytoid dendritic cells correlates with elevated T-regulatory cells in liver transplant tolerance. 2008/02
14.	総説	Dendritic cells, the liver, and transplantation. 2007/12
15.	原著	Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques. 2007/07
16.	原著	Induction of endotoxin tolerance inhibits alloimmune responses. 2006/11
17.	原著	Endotoxin modulates the capacity of CpG-activated liver myeloid DC to direct Th1-type responses. 2006/09
18.	原著	Liver sinusoidal endothelial cells that endocytose allogeneic cells suppress T cells with indirect allospecificity. 2006/09
19.	原著	Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells. 2006/03
20.	原著	Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice. 2005/07
21.	原著	Vascular closure staples for portal vein reconstruction in living-donor liver transplantation. 2005/07
22.	原著	Liver sinusoidal endothelial cells contribute to alloreactive T-cell tolerance induced by portal venous injection of donor splenocytes. 2005/02
23.	原著	Liver sinusoidal endothelial cells have a capacity for inducing nonresponsiveness of T cells across major histocompatibility complex barriers. 2005/02
24.	原著	Involvement of tumor necrosis factor-alpha receptor 1 and tumor necrosis factor-related apoptosis-inducing ligand-(TRAIL) receptor-2/DR-5, but not Fas, in graft injury in live-donor liver transplantation. 2004/11
25.	原著	Differential diagnosis between graft-versus-host disease and hemophagocytic syndrome after living-related liver transplantation by mixed lymphocyte reaction assay. 2004/07
26.	原著	Liver NK cells expressing TRAIL are toxic against self hepatocytes in mice. 2004/05
27.	原著	NOD/SCID mice engrafted with human peripheral blood lymphocytes can be a model for investigating B cells responding to blood group A carbohydrate determinant. 2003/10
28.	原著	Intraoperative near-infrared spectroscopy for evaluating hepatic venous outflow in living-donor right lobe liver. 2003/09
29.	原著	Construction of ectopic xenogeneic bone marrow structure associated with persistent multi-lineage mixed chimerism by engraftment of rat bone marrow plugs into mouse kidney capsules. 2003/05
30.	原著	Enzyme-linked immunospot assay for detecting cells secreting antibodies against human blood group A epitopes. 2003/02
31.	原著	Limited engraftment capacity of bone marrow-derived mesenchymal cells in xenogeneic bone marrow transplantation. 2003/02
32.	原著	Multiparameter flow cytometric mixed lymphocyte reaction assay using fluorescent cytoplasmic dye for assessing phenotypic property of T cells responding to allogeneic stimulation. 2003/02
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■ 学会発表

1.	Successful prophylaxis of antibody-mediated rejection by downregulation of C5 expression via RNA interference in a rat kidney transplant model. （ポスター，一般） 2021/06/04
2.	虚血再灌流障害関連拒絶反応におけるフラクタルカイン-CX3CR1シグナルに関する研究（ポスター，一般） 2019/10/10
3.	Fractalkine is crucial in ischemia reperfusion injury related to acute rejection in an allogeneic heart transplantation model. （ポスター，一般） 2019/06/02
4.	2次移植における、移植腎機能障害の臨床的検討（口頭発表，一般） 2010/06
5.	B細胞除去療法を施行したABO不適合移植における抗体関連型拒絶反応（口頭発表，一般） 2010/06
6.	Acute antibody-mediated rejection in living ABO-incompatible kidney transplantation: long-term impact and risk factors （口頭発表，一般） 2010/05
7.	Clinicopathological analysis of acute vascular rejection cases after renal transplantation （口頭発表，一般） 2010/05
8.	Lymphopenia-induced proliferation of lymphocytes results in chronic rejection of mice cardiac allografts （口頭発表，一般） 2010/05
9.	Lymphopenia-indued proliferation of lymphocytes results in chronic rejection of mice cardiac allografts （口頭発表，一般） 2010/05
10.	Marked improvement of the outcome of ABO-incompatible living kidney transplantation under current immunosuppressive （口頭発表，一般） 2010/05
11.	The effect of anti IL-6 receptor monoclonal antibody during acute and chronic rejection in a cardiac allograft transplantation murine model （口頭発表，一般） 2010/05
12.	バーチャルクロスマッチ陽性症例は抗体関連型拒絶が高率である（口頭発表，一般） 2010/01
13.	抗IL-6受容体抗体の臓器移植に対する有効性について基礎検討（口頭発表，一般） 2010/01
14.	腎移植後に尿路上皮癌を発症した一例（口頭発表，一般） 2010/01
15.	当院における2次腎移植の臨床的検討（口頭発表，一般） 2010/01
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全件表示(15件)

■ 学歴

1.	2000/04～2005/03	広島大学医学系研究科博士課程修了博士（医学）
2.	1989/04～1995/03	広島大学医学部卒業