Faculty Information - UCHIGATA Yasuko

Books

Published papers

Academic conference presentation

Main course titles

Research areas

Academic society memberships

Education

Academic & professional experience

（Last updated : 2024-01-31 15:59:44）

UCHIGATA Yasuko
Department School of Medicine(Tokyo Women's Medical University Adachi Medical Center), School of Medicine

Position Professor (Fixed Term)

■ Books

1.	Chapter contribution	Update information on type 1 diabetes in Children/adolescents and adults, J Diabetes Investig. 2023/01/19
2.	Single work	Association of serum bilirubin levels with development and progression of albuminuria, and decline in estimated glomerular filtration rate in patients with type 2 diabetes mellitus., Jounal of Diabetes investigation 2014/03
3.	Single work	Glycosuria「腎と透析　腎疾患治療マニュアル　2012-13　別刷」 2012
4.	Chapter contribution	Insulin autoimmune syndrome, Immunoendocrinology: Scientific and clinical aspects G Einsenbarth ed. 2011

■ Published papers

1.	Original article	Prognostic Impact of Statins on Patients With Peripheral Artery Disease With Elevated C-Reactive Protein Levels 2023/01/01
2.	Original article	Factors associated with hypoglycemia unawareness and severe hypoglycemia in type 1 diabetes mellitus patients 2022/07/23
3.	Original article	REGN-COV2 antibody cocktail in patients with SAS-CoV-1: Observational study from a single institution in Japan 2022/03/30
4.	Original article	Psychological Effects on Healthcare Workers during the COVID-19 Outbreak: A Single-center Study at a Tertiary Hospital in Tokyo, Japan. 2021/09
5.	Other	Universal testing for SARS-CoV-2 infection on admission among hospitalized emergency patients: A survey report from a single facility in Tokyo. 2021/09
6.	Original article	Clinical features of patients positive for SARS-CoV-2 by RT-PCR in a fever clinic for COVID-19; Comparison with negative PCR cases and comparison of the first and second waves. 2021/01
7.	Original article	Vitreous hemorrhage in diabetes patients with proliferative diabetic retinopathy undergoing hemodialysis. 2020
8.	Original article	Body weight reduction of 5% improved blood pressure and lipid profiles in obese men and blood glucose in obese women: A four-year follow-up observational study 2019/05
9.	Original article	Serum lipid management in patients with type 1 and type 2 diabetes: a hospital-based cohort study 2019
10.	Case report	A case of diabetic foot gangrene with stump ulcer after lower extremity amputation successfully treated with negative pressure wound therapy 2018/09
11.	Review article	The still persistent stigma around diabetes: is there something we can do to make it disappear? 2018/09
12.	Original article	Genetic differences between type 1 diabetes with and without other autoimmune diseases. 2018/04
13.	Original article	Glucagon-like peptide-1 receptor agonists reduced the low-density lipoprotein cholesterol in Japanese patients with type 2 diabetes mellitus treated with statins 2018/01
14.	Original article	Role of vitamin D in energy and bone metabolism in postmenopausal women with type 2 diabetes mellitus: A 6-month follow-up evaluation. 2018/01
15.	Original article	Association of total and differential white blood cell counts with physical energy expenditure 2017/11
16.	Original article	Renal Function after Intravitreal Administration of Vascular Endothelial Growth Factor Inhibitors in Patients with Diabetes and Chronic Kidney Disease. 2017/11
17.	Original article	The relationship between diabetes mellitus and depression:Analysis using the Diabetes Study from the Center of Tokyo Women's Medical University(DIACET) 2017/11
18.	Original article	Creation and Transplantation of an Adipose-derived Stem Cell (ASC) Sheet in a Diabetic Wound-healing Model 2017/08
19.	Original article	Quality of life in Japanease patients with type 1 diabetes and end-stage renal disease undergoing simultaneous pancreas and kidney translantation 2017/08
20.	Original article	The incidences of and risk factors for severe retinopathy requiring photocoagulation and albuminuria in Japanese patients with childhood-onset type 1 diabetes 2017/08
21.	Original article	Diabetes and gender 2017/07
22.	Original article	Xenogeneic transplantation of human adipose-derived stem cell sheets accelerate angiogenesis and the healing of skin wounds in a Zucker Diabetic Fatty rat model of obese diabetes 2017/06
23.	Original article	Giant retinal pigment epithelial tear associated with fluid overload due to end-stage diabetic kidney disease. 2017/04
24.	Original article	Brachial-ankle pulse wave velocity, but not ankle-brachial index, predicts all-cause mortality in patients with diabetes after lower extremity amputation. 2017/03
25.	Original article	Evaluation of vitreous levels of advanced glycation end products and angiogenic factors as biomarkers for severity of diabetic retinopathy 2017/03
26.	Original article	Evaluation of vitreous levels of advanced glycation end products and angiogenic factors as biomarkers for severity of diabetic retinopathy. 2017/03
27.	Original article	Four cases of type 1 diabetes mellitus showing sharp serum transaminase increases and hepatomegaly due to glycogenic hepatopathy. 2017/03
28.	Original article	Diabetes diagnostic thresholds of the glycated hemoglobin A1c and fasting plasma glucose levels considering the 5-year incidence of retinopathy. 2017/02
29.	Original article	Relationship between HLA haplotype and BMI change in Japanease slowly progressive type 1 diabetes 2017/02
30.	Original article	Effect of Hemoglobin levels and sex on HbA1c levels among Japanese population 2017
31.	Original article	Associations of HbA1c and fasting plasma glucose with incident diabetes: Implications for pre-diabetes thresholds in a Japanese population 2016/12
32.	Review article	Clinicophysiological outcomes after total pancreatectomy. 2016/12
33.	Original article	Relationship between diabetic nephropathy and depression: a cross-sectional analysis using the Diabetes Study from the Center of Tokyo Women's Medical University(DIACET) 2016/12
34.	Original article	Relationships between vitreous levels of soluble receptor for advanced glycation end products (sRAGE) and renal function in patients with diabetic retinopathy. 2016/11
35.	Original article	Screening for diabetic retinopathy using new mydriasis-free, full-field flicker ERG recording device. 2016/11
36.	Original article	Effects of statins on the kidneys in patients with type 2 diabetes 2016/09
37.	Review article	Insulin Autoimmune Syndrome Accompanied by Multiple Myeloma 2016/08
38.	Review article	Risk factors for sudden death and cardiac arrest at the onset of fulminant type 1 diabetes mellitus 2016/08
39.	Original article	Size effect of engineered islets prepared using microfabricated wells on islet cell function and arrangement. 2016/06
40.	Original article	Assessment of predictors of insulin therapy in patients with gestational diabetes diagnosed according to the IADPSG 2016/05
41.	Review article	Can restoring immune balance be the ultimate therapy for type 1 diabetes? 2016/05
42.	Review article	Swiching from subcutaneous insulin injection to oral vildagliptin administration in hemodialysis patient with type 2 diabetes:a polot study 2016/05
43.	Original article	The relationship between depressive symptoms and diabetic complications in elderly patients with diabetes: Analysis using the Diabetes Study fron the Center of Tokyo Women's Medical University (DIACET) 2016/04
44.	Review article	Improved incidence of end-stage renal disease of type 1 diabetes in japan,from a hospital-based survey 2016/03
45.	Review article	Can restoring immune balance be the ultimate therapy for type 1 diabetes? 2016/02
46.	Original article	Association of serum bilirubin levels with mortality in patients with diabetes initiating chronic hemodialysis:a competing risks analysis of a single-center cohort. 2016
47.	Original article	Allogeneic Transplantation of an Adipose-Derived Stem Cell Sheet Combined With Artificial Skin Accelerates Wound Healing in a Rat Wound Model of Type 2 Diabetes and Obesity 2015/08
48.	Review article	Changes in the prognosis of japanese patients who developed type 1 diabetes before the age of 30 years. 2015/08
49.	Original article	Association of birthweight with diabetes and insulin sensitivity or secretion in the Japanese general population 2015/07
50.	Original article	Clinical features of slowly progressive type 1 (insulin-dependent) diabetes mellitus: a comparative study based on degree of obesity at diagnosis of diabetes 2015/05
51.	Original article	Association between basal metabolic function and bone metabolism in postmenopausal women with type 2 diabetes. 2015
52.	Original article	Differences in risk factors for the onset of albuminuria and decrease in glomerular filtration rate in people with Type 2 diabetes mellitus: implications for the pathogenesis of diabetic kidney disease. 2015
53.	Review article	Severe Insulin-resistant Diabetes due to Insulin Antibodies Associated with Eosinophilia 2015
54.	Original article	Temporal changes in mean HbA1c in a general population: comparisons between 1997 and 2002, the Japan National Diabetes Surveys. 2015
55.	Original article	Efficacy of negative pressure wound therapy for the treatment of diabetic foot ulcer/gangrene 2014/06
56.	Original article	Effects of Age on Insulin Resistance and Secretion in Subjects without Diabetes 2014/05
57.	Original article	GLP-1-related proteins attenuate the effects of mitochondrial membrane damage in pancreatic beta cells 2014/04
58.	Original article	Impact of eicosapentaenoic acid/arachidonic acid ratio on left ventricular structure in patients with diabetes 2014/04
59.	Original article	A case of diabetes mellitus associated with severe sleep apnea and Prader-Willi syndrome 2014/03
60.	Original article	Association of serum bilirubin levels with development and progression of albuminuria, and decline in estimated glomerular filtration rate in patients with type 2 diabetes mellitus 2014/03
61.	Review article	Diagnostic criteria for acute-onset type 1 diabetes mellitus(2012):Report of the Committee of Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus. 2014/01
62.	Original article	Association between lung function and metabolic syndrome independent of insulin in Japanese men and women 2014
63.	Review article	Diagnostic criteria for acute-onset type 1 diabetes mellitus (2012): Report of the Committee of Japan Diabetes Society on the Research of Fluminant and Acute-onset Type1 diabetes mellitus 2014
64.	Original article	Evaluation of add-on therapy of sitagliptin in Japanese patients with type 2 diabetes under insulin therapy 2014
65.	Review article	Guidelines for diabetes mellitus: from the perspective of diagnosis and treatment. 2014
66.	Review article	Urinary type VI collagen as a predictor for the incidence of microalbuminuria in young patients with type 1 diabetes 2014
67.	Original article	The relation between contrast-induced nephropathy and the medication in patients with diabetes mellitus 2013/12
68.	Original article	Prediction of Retinopathy at 20Years After Onset in Younger-Onset Type 1 Diabetes Using Mean Metabolic Memory-Free HbA1c Values 2013/11
69.	Review article	Research:Complications Urinary type IV collagen as a predictor for the incidence of microalbuminuria in young patients with Type 1 diabetes. 2013/09
70.	Original article	Skin Autofluorescence Reflects Integration of Past Long-Term Glycemic Control in Patients With Type 1 Diabetes 2013/08
71.	Original article	Prevalence of retinopathy and its risk factors in a Japanese population 2013/07
72.	Original article	Prevalence of retinopathy and its risk factors in a Japanese population. 2013/07
73.	Review article	Comparison of spironolactone and trichlormethiazide as add-on therapy to renin-angiotensin blockade for reduction of albuminuria in diabetic patients 2013/05
74.	Review article	Comparison of spironolactone and trichlormethiazide as add-on therapy to renin-angiotensin blockade for reduction of albuminuria in diabetic patients 2013/05
75.	Review article	Diagnostic criteria for acute-onset type 1 diabetes mellitus(2012):Report of the Committee of Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus 2013/05
76.	Original article	Guidelines for the use of iodinated contrast media in patients with chronic kidney disease 2013/03
77.	Review article	The Influence of a Single Nucleotide Polymorphism within CNDP1 on Susceptibility to Diabetes Nephropathy in Japanesr Women with Type 2 Diabetes 2013/01
78.	Review article	Evaluation of stepwise insulin treatment as an add-on to current oral antidiabetic drugs therapy in Japanese patients with type 2 diabetes: STEADY study. 2013
79.	Original article	Whole gene deletion mutation of HNF1B and exonic aberration mutations of GCK and HNF1B in patients with MODY in Japan 2012/09
80.	Case report	A case of Type 2 Diabetes Mellitus with Insulin Allergy who was Successfully Treated with Corticosteroid for Nocturnal Hypoglycemia Possibly Caused by Insulin Antibody. 2012/07
81.	Original article	Prognostic Value of (123)I-Betamethyl-p-Iodophenyl-Pentadecanoic Acid Single-Photon Emission Computed Tomography in Diabetic Patients With Suspected Ischemic Heart Disease 2012/07
82.	Original article	Insulin sensitivity and secretion indices in Japanese subjects with normal and impaired glucose tolerance 2012/06
83.	Review article	Non-linear association between ankle-brachial pressure index and prevalence of silent cerebral infarction in japanese patients with type 2 diabetes 2012/05
84.	Original article	A new mitochondrial pH biosensor for quantitative assessment of pancreatic β-cell function 2012/04
85.	Original article	Prognostic value of I-123 BMIPP SPECT in diabetic patients with suspected ischemic heart disease 2012
86.	Review article	Report of the Committee of the Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus:New diagnostic criteria of fulminant type 1 diabetes mellitus(2012) 2012
87.	Review article	Report of the Committee of the Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus:New diagnostic criteria of fulminant type 1 diabetes mellitus(2012) 2012
88.	Original article	Arterial stiffness is associated with incident albuminuria and decreased glomerular filtration rate in type 2 diabetic patients. 2011/12
89.	Original article	Administration of insulin glargine thrice weekly by medical staff at a dialysis: a new insulin regimen for diabetic management in physically impaired patients undergoing hemodialysis. 2011/11
90.	Original article	Assessment of Cholesterol Absorption and Synthesis in Japanese Patients with Type-2 Diabetes and Lipid-Lowering Effect of Ezetimibe. 2011/02
91.	Original article	Differences in the humoral autoreactivity to zinc transporter 8 between childhood- and adult -onset type 1 diabetes in Japanese patients. 2011/02
92.	Original article	A 60-year old patient with mils complications who developed type 1 diabetes with coma at 1year and 7 months. 2011
93.	Original article	Association of urinary type IV collagen with GFR decline in young patients with type 1 diabetes. 2011
94.	Original article	Difference in the humoral autoreactivity to Zinc transporter 8 between childhood- and adult- onset type 1 diabetes in Japanese patients. 2011
95.	Original article	The relationship between the age of onset of type 1 diabetes and the subsequent development of a severe eating disorder by female patients. 2011
96.	Original article	The Research Committee on Type 1 Diabetes of the Japan Diabetes Society Type 1 diabetes and interferon therapy A nationwide survey. 2011
97.	Original article	Total and differential white blood cell counts, fasting insulin concentrations, and components of metabolic syndrome in Japanese men and women: the Kurihashi Lifestyle Cohort Study 2011
98.	Original article	Incidence and development of diabetic microangiopathy of fulminant type 1 diabetes--comparison with non-fulminant type 1 diabetes 2010
99.	Original article	Nationwide survey to compare the prevalence of transient elevation of liver transaminase during treatment of diabetic ketosis or ketoacidosis in new-onset acute and fulminant type 1 diabetes mellitus 2008/01
100.	Original article	Chorea and Broca aphasia induced by diabetic ketoacidosis in a type 1 diabetic patient diagnosed as Moyamoya disease 2005/05
101.	Original article	Mutation in the mitochondrial tRNA(leu) at position 3243 and spontaneous abortions in Japanese women attending a clinic for diabetic pregnancies. 1995/07
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■ Academic conference presentation

1.	Association of Anti-GAD Antibody Positivity Measured by RIA and ELISA with Clinical Characteristics in Patients with Type 1 Diabetes 2018/06/25
2.	A novel mutation in the IPF-1/PDX-1 gene identified in a Japanese family with MODY. 2017/09/13
3.	Glucagon-Like Peptide-1 Receptor Agonists Reduce Serum LDL Cholesterol Levels via LDL Receptor in Mice and Type 2 Diabetes Patient 2017/06/10
4.	Newly identified mutation in 5'UTR of HNF4A in a case of MODY3 2017/05/20
5.	Impact of the peer counseling for dissolving a negative cognition toward diabetes 2016/10/30
6.	Effects of denosumab on fat and basal metabolism in postmenopausal women with type 2 diabetes 2016/09/19
7.	Impact of eicosapentanoic acid / arachidonicacid ratio on diastolic blood pressure in patients with type 2 duabetes 2016/06/12
8.	HbA1c, Fasting Plasma glucose, and Incident Retinopathy: Evaluation of Diagnostic Cut-off for Diabetes. 2016/06
9.	Prevalence of MODY subtype and clinical characteristics in patients with early onset diabetes in Japanese 2016/04/05
10.	Relationships of resting energy expenditure and bone metabolism in postmenopausal Japanese women with type 2 diabetes: 6-month follow-up with vitamin D supplementation 2015/10/11
11.	Energy expenditure from daily physical activity and risk of developing diabetes and change in cardiovascular risk factors 2015/09/16
12.	Genetic variants in the lanosterol synthase gene are associated with type 2 diabetes 2015/06/08
13.	Development and Validation of a Prediction Model for Future Type2 Diabetes in Japan. 2015/06
14.	Predictors of insulin therapy in patients with gestational diabetes diagnosed according to the IADPSG criteria 2015/03/15
15.	Longitudinal association of retinopathy and glucose metabolism in a Japanese population. 2014/09
16.	Relationship between energy expenditure and bone metabolism in post-menopausal women with Type 2 Diabetes 2014/07/25
17.	Allogeneic Transplantation with the Comcomitant Use of Adipose-Derived-Stem-Cell (ADSC) Sheets and Artificial Dermis Accelerated the Wound Healing of Rat Diabetic Ulcers 2014/06/15
18.	Noodle intake and abdominal obesity in Japanese men and women. 2014/06
19.	The significant influence of skin AF value on microvascular complications through retrospective study in Japanese patients with type 2 diabetes. 2013/12/02
20.	Does birth weight affect insulin sensitivity and secretion and the prevalence of diabetes in a Japanese general population? 2013/12/01
21.	Postprandial blood glucose to identify diabetes by HbA1c. 2013/12/01
22.	Do haemoglobin levels affect HbA1c levels in non-anemic and non-diabetes Japanese? 2013/11/30
23.	Does birth weight affect insulin sensitivity and secretion and the prevalence of diabetes in a Japanese general population? 2013/09/26
24.	Identification of HbA1c cutoff for pre-diabetes from incidence of diabetes in a Japanese population 2013/09/24
25.	Relationship between haemoglobin and glycated haemoglobinA1c in a Japanese population. 2013/09/24
26.	Diabetic retinopathy of twin pregnancy in Japanese patients 2013/09
27.	Adipose derived stromal cell sheet with artificial dermis accelerates skin wound healing 2013/07/08
28.	Application of MODY probability calculator for Japanese patients with MODY3 2013/06/22
29.	Genetic Backgrounds of patients with type 1 diabetes associated with systemic or organ-specific autoimmune disease. 2013/06/22
30.	Lower HDL Cholesterol Levels are Associated With the Incidence of Lower-Extremity Amputation in Patients With Diabetic Ulcer/Gangrene 2013/06/21
31.	Impact of Eicosapentaenoic acid/Arachidoniacid ratio on left ventricular struacture in diabetic patients 2013/06/15
32.	Left atrial diameter of each stage of diabetic nephropathy in type 2 diabetes 2013/06/14
33.	Efficacy of Concomitant in Japanese Type 2 Diabetes Mellitus Patient With Insulin and Sitagliptin, a DPP-4 inhibitor. 2013/06
34.	Effects of Glucagon like protein (GLP)-1 on mitochondrial function in cultured β cells 2013/04/24
35.	5-Year Temporal Change in HbA1c in Japanese General Population 2012/11/27
36.	Effect of exercise on glucose tolerance and total white blood cell count in Japanese male wokers 2012/11/26
37.	Relationship between HbA1c or glycated albumin and dircardian blood glucose using continuous glucose monitoring in diabetic patients undergoing hemodialysis 2012/11/03
38.	Liraglutide ameliorates the ethidium bromide induced mitochondrial dysfunction in cultured β cells 2012/11
39.	The significant influence of integration of glycemic control on skin AF value through retrospective and prospective study in Japanese patients with type 1 diabetes-1st cohort report- 2012/10/04
40.	Whole exome sequencing identifiesCUL9 as a MODY-X gene 2012/10/02
41.	Casual blood glucose to identify diabetes as identified by HbA1c. 2012/10
42.	Obesity modifies the association between leptin levels and decline in kidney function in patients with type 2 diabetes 2012/06/09
43.	Genome-wide association study of insulin autoimmune syndrome. 2012/06/01
44.	Total and differential white blood cell counts, fasting insulin concentrations, and metabolic syndrome in men and women 2011/12/05
45.	The relationship between the skin AGEs and color or elasticity in Japanese diabetic and non-diabetic subjects 2011/12/04
46.	Association of total and differential white blood cell counts with physical energy expenditure 2011/12/02
47.	A stepwise insulin treatment as add-on to current oral antidiabetic drugs therapy in Japanese patients with type 2 diabetes: Steady Study 2011/12
48.	Insulin sensitivity and insulin secretion indices in Japanese subjects with normal and impaired glucose tolerance 2011/12
49.	Predictive Factors for the Progression to End-Stage Renal Disease in Diabetic Patients with Chronic Kidney Disease Stage 4-5 2011/11
50.	Serum bilirubin levels and the progression of diabetic kidney disease in patients with type 2 diabetes 2011/09
51.	What do we know about type 2 diabetes in children/adolescence? 2011/07/24
52.	Impact of hsCRP and Adipo-cytokine in Coronary Artery Calcifications in Type 2 Diabetes-Using Multidetector Computed Tomography(MDCT)- 2011/06/19
53.	The Investigation of Daily Profile of Blood Glucose Analyzed with CGMS in Well-Controlled Patients with Type 1 Diabetes between with and without Unaware Severe Hypoglycemia. 2011/06/17
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■ Research areas

Metabolism and endocrinology, Metabolism and endocrinology, Metabolism and endocrinology

■ Academic society memberships

1.	～	American Diabetes Association (ADA)
2.	～	International Diabetes Federation(IDF)
3.	～	International Society for Pediatric and Adolescent Diabetes (ISPAD)

■ Education

1981/03

〔Doctoral course〕, Kanazawa University, Completed,

■ Academic & professional experience

1.	2011/05～	Manager(Dean)
2.	2004/10～	Professor
3.	1996/10～2004/09	Associate Professor
4.	1987/04～1992/02	Research Assistant