Faculty Information - NAKANISHI Toshio

（Last updated : 2022-05-18 09:16:02）

NAKANISHI Toshio
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Department of Surgery, Division of Pediatric Cardiology and Adult Congenital Cardiology

Position Professor (Fixed Term)

■ Published papers

1.	Original article	Functional Evaluation of Human Bioengineered Cardiac Tissue Using iPS Cells Derived from a Patient with Lamin Variant Dilated Cardiomyopathy. 2022/03/30
2.	Case report	Complete remission from post-heart transplant lymphoproliferative disorder: A case report 2021/01/11
3.	Original article	Mid- to long-term surgical outcomes of partial anomalous pulmonary venous connection 2021/01
4.	Original article	Silibinin Upregulates CXCR4 Expression in Cultured Bone Marrow Cells (BMCs) Especially in Pulmonary Arterial Hypertension Rat Model. 2020/05
5.	Original article	Prevalence and risk factors of sleep apnea in adult patients with congenital heart disease. 2019/05
6.	Original article	Silibinin efficacy in a rat model of pulmonary arterial hypertension using monocrotaline and chronic hypoxia. 2019/04
7.	Original article	Bioelectrical impedance analysis in the management of heart failure in adult patients with congenital heart disease. 2019/03
8.	Original article	Role of BRCA1-associated protein (BRAP) variant in childhood pulmonary arterial hypertension. 2019/01
9.	Original article	Influence of pregnancy on cardiac function and hemodynamics in women with Ebstein's anomaly. 2018/05
10.	Original article	Pregnancy and delivery outcomes from patients with repaired anomalous origin of the left coronary artery from the pulmonary artery. 2018/05
11.	Review article	Statement for heart transplantation (JCS 2016) 2018/01
12.	Original article	Clinical implications of eicosapentaenoic acid/arachidonic acid ratio (EPA/AA) in adult patients with congenital heart disease. 2017/12
13.	Original article	Outcomes from anomalous origin of the left coronary artery from the pulmonary artery repair: Long-term complications in relation to residual myocardial abnormalities. 2017/11
14.	Original article	Significance of right atrial tension for the development of complications in patients after atriopulmonary connection Fontan procedure: potential indicator for Fontan conversion. 2017/07
15.	Original article	Prognostic predictive value of gene mutations in Japanese patients with hypertrophic cardiomyopathy. 2017/06
16.	Original article	Dual origin multiple plexus-like coronary to pulmonary artery fistulas - Consideration of their etiology and therapeutic strategy. 2017/05
17.	Original article	Long-term Outcomes after Truncus Arteriosus Repair: A Single-center Experience for More than 40 Years. 2016/12
18.	Original article	Prognostic value of multiple biomarkers for cardiovascular mortality in adult congenital heart disease: comparisons of single-/two-ventricle physiology, and systemic morphologically right/left ventricles 2016/11
19.	Original article	Arterial Switch Operation With and Without Coronary Relocation for Intramural Coronary Arteries. 2016/10
20.	Original article	Sildenafil reduces pulmonary vascular resistance in single ventricular physiology 2016/10
21.	Original article	Blood coagulation abnormalities and the usefulness of D-dimer level for detecting intracardiac thrombosis in adult Fontan patients 2016/09
22.	Original article	Risk factors and serological markers of liver cirrhosis after Fontan procedure. 2016/09
23.	Original article	Outcomes in children with advanced heart failure in Japan: importance of mechanical circulatory support. 2016/07
24.	Case report	Successful catheter ablation of ventricular tachycardia in a patient with congenitally corrected transposition of great arteries after double switch operation. 2016
25.	Original article	High prevalence of cardiovascular risk factors in children and adolescents with Williams-Beuren syndrome. 2015/09
26.	Case report	Absence of a resetting phenomenon suggests that a sling works as a part of the supraventricular tachycardia circuit involving twin atrioventricular nodes: A case of corrected transposition of the great arteries 2015/07
27.	Original article	Relationships among red cell distribution width, anemia, and interleukin-6 in adult congenital heart disease. 2015/05
28.	Original article	Therapeutic Efficacy of Valproic Acid in a Combined Monocrotaline and Chronic Hypoxia Rat Model of Severe Pulmonary Hypertension. 2015/01
29.	Case report	Successful Fontan conversion combined with cardiac resynchronization therapy for a case of failing Fontan circulation with ventricular dysfunction. 2014/11
30.	Case report	Ventricular assist device implantation late after double switch operation for L-transposition of the great arteries. 2014/11
31.	Original article	Stenting for pulmonary artery stenosis complicated by univentricular physiology: Subanalysis of JPIC stent survey. 2014/10
32.	Original article	Acute Rupture of Chordae Tendineae of the Mitral Valve in Infants: A Nationwide Survey in Japan Exploring a New Syndrome. 2014/09
33.	Original article	RAF1 mutations in childhood-onset dilated cardiomyopathy. 2014/06
34.	Original article	Mutations of NOTCH3 in childhood pulmonary arterial hypertension. 2014/05
35.	Original article	Soluble ST2 and N-terminal pro-brain natriuretic peptide combination-Useful biomarker for predicting outcome of childhoodpulmonary arterial hypertension- 2014/02
36.	Original article	Cardiac channelopathies associated with infantile fatal ventricular arrhythmias: from the cradle to the bench. 2014/01
37.	Original article	Mutations in the cardiac troponin T gene show various prognoses in Japanese patients with hypertrophic cardiomyopathy. 2013/11
38.	Review article	3D-culture system for heart regeneration and cardiac medicine 2013/09
39.	Review article	Cell shape and cardiosphere differentiation: a revelation by proteomic profiling. 2013/09
40.	Original article	Complications of cardiac catheterization in adults and children with congenital heart disease in the current era 2013/05
41.	Case report	Assessment of mechanical dyssynchrony in fulminant myocarditis 2013/03
42.	Original article	Hesr2 Knockout Mice Develop Aortic Valve Disease With Advancing Age 2013/03
43.	Original article	Long-term and Low-dose Steroid Therapy for Cardiomyopathy in Duchenne Muscular Dystrophy Patients 2013/01
44.	Original article	Transrepression activity of T-box1 in a gene regulation network in mouse cells. 2012/12
45.	Original article	Versican is required for Neural Crest Cells 2012/06
46.	Original article	Close monitoring of initial enzyme replacement therapy in a patient with childhood-onset Pompe disease 2012/02
47.	Original article	Surgical Results for Functional Univentricular Heart With Total Anomalous Pulmonary Venous Connection Over a 25-Year Experience 2012/02
48.	Case report	Congenital giant cardiac tumor with severe left-ventricular inflow and outflow obstruction and arrhythmia treated with pulmonary artery banding and long-term amiodarone infusion 2012
49.	Original article	Prospective in vitro models of channelopathies and cardiomyopathies 2012
50.	Original article	115 6 1073 1077 2011/06
51.	Original article	Histopathological aspects of cardiac biopsy in peciiatric patients with dilated cardiomyopathy 2011/06
52.	Original article	Asynchronous contraction of the 2 ventricles caused by ventricular pacing after a Fontan-type operation in a patient with a biventricular heart 2011
53.	Original article	Effects of transforming growth factor-β3 and matrix metalloproteinase-3 on the pathogenesis of chronic mitral valvular disease in dogs 2011
54.	Other	Aortic Dilatation (AD) and Bentall Operation in Tetralogy of Fallot (TOF) 2010
55.	Other	Arrhythmia in Patients With Corrected Transposition of the Great Arteries Before and After Double Switch Operation 2010
56.	Other	Comprehensive Genetic Approach for Congenital Heart Disease Revealed Sequence Variants in Genes Encoding Cardiac Transcription Factors 2010
57.	Other	Constriction of Ductus Arteriosus by Antidiabetic Sulfonylurea Drugs in Fetal Rats 2010
58.	Other	Electrophysiological management for atrial (AT) and ventricular tachycardia (VT) long after repair of tetralogy of Fallot (TOF) 2010
59.	Other	Expression of Transforming Growth Factor-beta in the Liver of Patients Long after Fontan Operation 2010
60.	Other	Histopathological aspects of cardiac biopsy in pediatric patients with dilated cardiomyopathy 2010
61.	Original article	In vivo dilatation of the ductus arteriosus induced by furosemide in the rat 2010
62.	Other	Letter to the editor : Asynchronous contraction of the 2 ventricles caused by ventricular pacing after a Fontan-type operation in a patient with a biventricular heart 2010
63.	Other	Long-term results of Catheter Ablation for Supraventricular Tachycardia Involving Twin Atrioventricular Nodes in Patients with Complex Heart Disease 2010
64.	Other	Medical and Surgical Management of Adult Atrial Septal Defect Early and Late Results of Catheter Ablation of Atrial Tachycardia Occurring Late after Surgical Closure of Atrial Septal Defects 2010
65.	Other	Predictors of Mortality and the Effect of Disease Specific Therapy on Survival in Adult Patients With Eisenmenger Syndrome 2010
66.	Other	Risk Factor and Serological Markers of Liver Cirrhosis In Patients After Fontan Operation 2010
67.	Original article	Increased P-Selectin Expression on Platelets and Decreased Plasma Thrombomodulin in Fontan Patients 2009
68.	Original article	Developmental changes in the expression of voltage-gated potassium channels in the ductus arteriosus of the fetal rat 2007/10
69.	Original article	Beta-Blocker Therapy for Cardiac Dysfunction in Patients With Muscular Dystrophy 2006/08
70.	Original article	Cardiac involvement in Fukuyama-type congenital muscular dystrophy 2006/06
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■ Academic conference presentation

1.	Contractile measurement of human bioengineered cardiac tissue using iPS cells derived from dilated cardiomyopathy patients with lamin variant. 2020/07/30
2.	iPS cell-derived cardiac tissue from dilated cardiomyopathy patients with lamin variant showed impaired systolic function. 2019/11/17
3.	Contractile measurement of human bioengineered cardiac tissue using iPS cells derived from dilated cardiomyopathy patients with lamin variant. 2019/11/14
4.	Contractile measurement of human bioengineered cardiac tissue using iPS cells derived from dilated cardiomyopathy patients with lamin variant. 2019/09/07
5.	Functional evaluation of human bioengineered cardiac tissue using iPS cells derived from dilated cardiomyopathy patients with lamin variant. 2019/06/04
6.	Pulmonary artery tear: how to manage? 2019/01/09
7.	Pulmonary and Systemic Circulation Long After Fontan in Univentricular Heart 2018/08/31
8.	RVOT and Right Heart Lesions 2018/02/03
9.	Special Considerations in PDA Closure 2018/01/31
10.	Managment of critical CHD 2017/11/03
11.	Ruptured Sinus of Valsalva-approach to succesful closure 2017/10/26
12.	Intramural coronary artery associated with transposition of great arteries : preoperative diagnosis and prognosis. 2017/04/01
13.	Long-Term Outcomes of the Fontan Operation: Forty Years of Experience at a Single Institute 2017/03/18
14.	Experience of ADO-II 2017/01/28
15.	Method and Techniques in Retrieval of Closure Device 2017/01/27
16.	Septal defects: From embryology to morphology. 2017/01/03
17.	Bioelectrical Impedance Analysis Is Useful For The Management Of Heart Failure And Prediction Of Cardiac Events In Adult Patients With Congenital Heart Disease 2016/11/14
18.	A case of visual disorder prolonged after cardiopulmonary arrest 2016/05/15
19.	Impact of Novel Balloon Catheter on Static Balloon Atrial Septostomy With Double Balloon Technique in Infants With Congenital Heart Disease 2016/01/30
20.	Radiofrequency catheter ablation of supraventricular tacycardia in the patients after Fontan surgery 2016/01/29
21.	Transcatheter closure for ASD with pulmonary hypertension 2016/01/29
22.	Glibenclamide Closes Premature Fetal Ductus Arteriosus in Rats 2015/09/18
23.	The Effects of Cardiac Resynchronization Therapy Using Transvenous Approach on Clinical Outcome in Patients with Systemic Right Ventricle Failure 2015/04/26
24.	Clinical Implication of Serum TGF-b Levels in Patients with Fontan Physiology 2015/04/25
25.	A case of polysplenia complicated with pulmonary hypertension and extrahepatic portosystemic shunt 2015/01/18
26.	A case report that was able to give birth after David operation for Marfan syndrome complicated with annuloaortic ectasia. 2015/01/18
27.	Influence on cardiac function after the delivery in postoperative Bland-White-Garland syndrome patients. 2015/01/18
28.	Reoperation for adult congenital heart disease-its speciality and check point- 2015/01/18
29.	Contents of Transitional Care in Patients with Congenital Heart Disease 2015/01/17
30.	Outcome of ablation for supraventricular tachycardia in adults underwent Fontan operation 2015/01/17
31.	Pacing device implantation for patients with complex heart disease 2015/01/17
32.	Protein-losing enteropathy(PLE) after the Fontan operation: Hemodynamics and treatment strategy 2015/01/17
33.	Pulmonary valve perforation in pulmonary atresia: What are the problems in the ICU? 2015/01/16
34.	Physiopathology of PAH: from theory to practice. 2015/01/15
35.	The physiopathology of RVOT and RVOT obstruction. 2015/01/15
36.	Clinical Significance of Impaired Vascular Endothelial Function in Patients After Fontan Procedure. 2014/11/19
37.	Catheter Ablation of Supraventricular Tachycardia in Patients With Total Cavopulmonary Connection. 2014/11/18
38.	Lower Heart Rates are Associated with Better Mid-term Outcomes in Fontan Patients. 2014/11/18
39.	Valproic Acid, a Class 1 Histone Deacetylase Inhibitor, Suppresses the Development of Severe Pulmonary Hypertension in Rats. 2014/11/17
40.	Factors Associated with Glucose Intolerance and Abnormal Lipid Metabolism in Fontan Patients. 2014/11/16
41.	Prognostic Value of Multiple Biomarkers on Mortality in Adults Congenital Heart Disease: Comparison of Single- and Two-Ventricle Physiology. 2014/11/16
42.	The long term results of double switch operation for congenitally corrected transposition of the great arteries. 2014/08/30
43.	The importance of right atrium tension in patients after atriopulmonary Fontan procedure 2014/05/23
44.	Transseptal Perforation for Radiofrequency Catheter Ablation in Patients with Fontan Procedure 2014/05/23
45.	Pharmacokinetics and Pharmacodynamics of Tolvaptan in Children with Congenital Heart Disease and Water Retention Resistant to Conventional Diuretics 2014/04/30
46.	Teaching about life and death to primary school students by a pediatrician. 2014/04/12
47.	Seeking the Ideal Cooperative Structure with Multidisciplinary Experts for Adult Patients with Congenital Heart Disease 2014/03/21
48.	Can availability of pulmonary vasodilators justify lowering thresholds for operation ? 2014/03/08
49.	The long term results of double switch operation for congenitally corrected transposition of the great arteries. 2014/03/07
50.	Early Detection of Pediatric Idiopathic Pulmonary Arterial Hypertension by School Electrocardiography Screening:A Nationwide Survey in Japan 2013/11/20
51.	Sildenafil Reduces Pulmonary Vascular Resistance in Patients With Single Ventricular Physiology 2013/11/20
52.	Ten, 20, and 30-Year Outcomes of Patients After Fontan Operation 2013/11/20
53.	Venous Flow Dynamics Rather Than Venous Pressure is Important for the Development of Liver Fibrosis After Atriopulmonary Fontan Procedure 2013/11/20
54.	Tolvaptan Improves Water Retention in Children Especially with Single Ventricle Physiology 2013/11/17
55.	Clinical impact of preoperative electrophysiological intervention on postoperative supraventricular tachycardia events following Fontan procedure 2013/09/03
56.	Catheter ablation of supraventricular tachycardia in patients with total cavopulmonary connection 2013/09/01
57.	Developmental Difference in Maturation of Sarcoplasmic Reticulum and Contractile Proteins in the Large Blood Vessels Influences Their Contractility 2013/07/14
58.	The role of thyroid hormone in developing heart the 46th annual meeting for the Japanese 2013/05/30
59.	Basic research from Cardiologist's view 2013/05/24
60.	Fontan pulmonary circulation: need for catheter and medical interventions 2013/05/24
61.	The preotic neural crest directly contributes to the coronary arteries 2013/05/16
62.	Left Ventricular Assist Device Implantation to a Biventricular Failure Patient of Corrected Transposition of the Great Arteries after Anatomical Repair 2013/04/26
63.	Multi-center studies on PH,Fontan,and cardiomyopathy in Japan 2013/03/23
64.	Histopathological Features of Massive Mitral Regurgitation due to Rupture of Chordae Tendineae in Infants: Nationwide Survey in Japan 2013/03/15
65.	Planned pregnancy and the TCPC 2013/02/21
66.	ICD therapy for ventricular tachycardia and sudden death in adults with congenital heart disease 2013/01/20
67.	Morphology of VSDs 2013/01/10
68.	Clinical Outcomes of Mutation Carriers in Pulmonary Arterial Hypertension in Children 2012/11/07
69.	Up to 39 Year's of Follow-up After Repair of Truncus Arteriosus 2012/11/07
70.	Exercise Physiology and Determinants of Exercise Capacity in Patients With Fontan Circulation 2012/11/06
71.	Double Gene Mutations in Long QT Syndrome Can Cause Significantly Increased Cardiac Event During Childhood 2012/11/04
72.	Management of heart failure in adults with congenital heart disease 2012/08/09
73.	Surgical outcome for simple total anomalous pulmonary venous connection in infant 2012/07/05
74.	Long term results for repair of Persistent Arterial Trunk 2012/05/25
75.	Radiofrequency catheter ablation for atrial tachycardia in patients with complex congenital heart disease after intracardiac operation 2012/05/23
76.	Vitamin D kinetics and parathyroid function in patients with congenital heart disease 2012/05/23
77.	Heart Failure in Elderly Patients with ASD 2012/04/26
78.	ACHD Program in Japan:Future Scope of Improvement Through Nationwide ACHD Network 2012/04/21
79.	Long-Term Outcome and Future Perspectives 2012/04/21
80.	Clinical Impact of the Lung Function in Adult Patients Late after Fontan Operation 2012/04/06
81.	Right Heart Volume Overload after Atrial Septal Defect Closure Using Amplatzer Septal Occuluder 2012/04/05
82.	Manegement of RVOT branch PA stenosis after TOF surgery 2012/04
83.	Catheter Ablation and Defibrillator Device Therapy of Tachy-arrhythmias in Adult Patients with Congenital Heart Disease Long after the Surgical Repair 2012/03/18
84.	Thrombolitic Event and Anticoagulant Therapy Long after the Fontan Operation 2012/03/17
85.	A Nationwide Group Study for Establishment of Clinical Regimens and Education Programs for Adult Congenital Heart Disease 2012/03/16
86.	Comparison of visceral patterns between polysplenia and asplenia syndrome 2012/03/01
87.	The results of radiofraquency catheter ablation in patients of complex congenital heart disease after intracardiac surgery for artrial tachycardia 2012/01/14
88.	Hemodynamics in ASD 2012/01
89.	Japan experience of perforation 2012/01
90.	Special Lecture2:ASD with PAH in Adults:Evaluation and Treatment 2011/11/26
91.	Daily Physical Activity in Patients After a Fontan Operation Improves Functional Capacity,Which is Related to Endothelial Function and Skeletal Muscle Hemodynamics 2011/11/16
92.	Session Title:Cardoac Surgery,Catheter Intervention and in Between. 2011/11/15
93.	Developmental Difference in Maturation of Sarcoplasmic Reticulum in the Large Blood Vessels Influences Their Contractility 2011/11/14
94.	Long-Term Survival and Quality of Life of Patients with Chromosome 22q11.2 Deletion Syndrome:A Multi-Center Study 2011/11/13
95.	Naturally Occurring L138Q Mutation in the Voltage-gated Potassium Channel 1.5 Impairs the Channel Activity 2011/08/04
96.	Naturally Occurring L138Q Mutation in the Voltage-gated Potassium Channel 1.5 Impairs the Channel Activity 2011/08/04
97.	Clinical Features of Compound and Double Mutations in Patients with Hypertrophic Cardiomyopathy 2011/08
98.	LIVE CASES 2011/07/25
99.	Naturally Occurring Mutations in the Voltage-gated Potassium Channel 1.5 2011/07/07
100.	Surgical results for functional univentricle with TAPVC over a 25-year period 2011/07/06
101.	Long-Term Results of the Mechanical Valve Replacements in Congential Heart Valve Diseases 2011/06
102.	Mid-long Term Surgical Outcome of Patial AnomalousPulmonary Venous Connection 2011/06
103.	OUTCOME FOR GRADUAL BILATERAL PULMONARY ARTERY BANDING WITH ABSORBABEL SUTURE FOR HYPOPLASTIC LEFT HEART AND VARIANT 2011/06
104.	The cardio renal anemia syndrome in adult patients with congential heart disease 2011/05/18
105.	The Clinical implication of serum uric acid levels in adult patients with congenital heart disease 2011/05/18
106.	The Variation of pulmonary lobation in patients with polysplenia syndrome in relation to spleen laterality 2011/05/13
107.	Treating the volume loaded RV:effectiveness and timing in currently used strategies 2011/05/09
108.	Pulmonary Artery Stenosis 2011/05/06
109.	Hesr2 disrupted mice develop aortic valve disease with advancingage 2011/05/05
110.	Special techniques:transeptal puncture 2011/05/05
111.	Anatomy of Atrial Septal Defect and 3D Imaging 2011/04/28
112.	CHD Session 2011/04/28
113.	Anatomy and 3D Imaging of ASD and Placement of the Occlusion Devide 2011/01/08
114.	Pulmonary venous abnormality in congenital heart disease (CHD): Clue of surgical approach by using MDCT. 2010/11/28
115.	Current models of collaboration in Japan 2010/09
116.	Aortic Dilatation (AD) and Bentall Operation in Tetralogy of Fallot (TOF) 2010/07
117.	Electrophysiological management for atrial (AT) and ventricular tachycardia (VT) long after repair of tetralogy of Fallot (TOF) 2010/07
118.	Results after Fontan conversion with arrhythmia surgery and pacemaker therapy 2010/07
119.	Constriction of Ductus Arteriosus by Antidiabetic Sulfonylurea Drugs in Fetal Rats 2010/06
120.	(Moderator) CVS.303 Diastolgy in Congenital Heart Disease 2009/11
121.	Total management of patients with congenital anomaly face symdrome and Williams syndrome,from newborn to adulthood 2009/10
122.	Ventricular performance inlong-term survivors after Fontan operation 2009/10
123.	Post Kawasaki Disease: How to follow these patients 2009/06
124.	The long term results of senning operation 2009/06
125.	Pediatric cardiology 2009/05
126.	Tenascin-C expression and neurla crest are associated with formation of the coronary orifice 2009/05
127.	TGF-b3 and MMP3 contribute to pathogenesis of myxomatous mitral valve in canine 2009/05
128.	Chronic Kidney Disease in Adult Congenital Heart Disease 2009/03
129.	Management of "Anticipated" Admissions in Adult Congenital Heart Disease Clinic.Symposium 19 Patient Management System for Adult Congenital Heart Disease 2009/03
130.	Systemic Venous Collateral Channels after the Fontan Procedures: Predictors and Clinical Course 2009/03
131.	initial efficacy of enzyme replacement therapy for a patient with childhood-onset Pompe disease 2007/11/29
132.	Clinical and psychosoial problems of a Duchenne muscular dystrophy carrier 2004/07
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