Faculty Information - IKUTA Soko

（Last updated : 2024-02-09 13:08:51）

IKUTA Soko
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Department of Neurosurgery

Position

■ Books

1.	Chapter contribution	Neurophysiological Monitoring and Awake Craniotomy for Resection of Intracranial Gliomas., Progress in Neurological Surgery vol.30, Intracranial Gliomas Part I - Surgery 2017/12
2.	Chapter contribution	MRI Based Sulcal Pattern Analysis for Diagnosis and Clinical Application in Neurosurgery, Computer Aided Surgery, Proceedings in Information and Communications Technology 2012
3.	Chapter contribution	Advanced Surgical Management of Gliomas: Technological Requirements, Concept of Information-guided Resection, and Clinical Results., Diagnostic Techniques and Surgical Management of Brain Tumors 2011

■ Published papers

1.	Original article	Differentiation of astrocytoma between grades II and III using a combination of methionine positron emission tomography and magnetic resonance spectroscopy. 2023/07
2.	Review article	A multicenter, randomized, placebo-controlled phase IIb trial of an autologous formalin-fixed tumor vaccine for newly diagnosed glioblastomas. 2023/01
3.	Original article	Relationship between characteristics of glioma treatment and surgical site infections. 2022/12/31
4.	Original article	Radiological Prediction of Isocitrate Dehydrogenase (IDH) Mutational Status and Pathological Verification for Lower-Grade Astrocytomas. 2022/07
5.	Review article	Cutting-edge Information Guided Surgery Created by Hyper SCOT 2019/11
6.	Original article	Role of photodynamic therapy using talaporfin sodium and a semiconductor laser in patients with newly diagnosed glioblastoma. 2019/11
7.	Case report	Usefulness of positron emission tomography for differentiating gliomas according to the 2016 World Health Organization classification of tumors of the central nervous system. 2019/08/16
8.	Original article	Tumor recurrence patterns after surgical resection of intracranial low-grade gliomas. 2019/07/30
9.	Original article	Sonodynamic Therapy with Anticancer Micelles and High-Intensity Focused Ultrasound in Treatment of Canine Cancer 2019/05/21
10.	Review article	Neurosurgery and Development of Medical Devices Based on Medical-Engineering Collaboration 2019/02
11.	Original article	Machine-Learning Approach for Modeling Myelosuppression Attributed to Nimustine Hydrochloride 2018/12
12.	Original article	Threshold of the extent of resection for WHO Grade III gliomas: retrospective volumetric analysis of 122 cases using intraoperative MRI 2018/07
13.	Original article	Threshold of the extent of resection for WHO Grade III gliomas: retrospective volumetric analysis of 122 cases using intraoperative MRI 2018/07
14.	Original article	Evaluation of DNA ploidy with intraoperative flow cytometry may predict long-term survival of patients with supratentorial low-grade gliomas: Analysis of 102 cases. 2018/05
15.	Review article	Further Development of Smart Treatment Room SCOT to Realize Intraoperative Quick Judgment and Decision Making in the Operation 2017/10
16.	Original article	Modified rapid immunohistochemical staining for intraoperative diagnosis of malignant brain tumors. 2017/10
17.	Original article	Effects of photodynamic therapy with talaporfin sodium on squamous cell carcinoma and sarcoma cells 2017/06
18.	Original article	Volumetric Analysis Using Low-Field Intraoperative Magnetic Resonance Imaging for 168 Newly Diagnosed Supratentorial Glioblastomas: Effects of Extent of Resection and Residual Tumor Volume on Survival and Recurrence 2017/02
19.	Review article	Photodynamic Therapy for Malignant Brain Tumors 2016/11
20.	Other	Experience with the Investigator Initiated Trial (IIT) and Medical Engineering Human Resource Development from the Clinical Standpoint 2015/08
21.	Review article	Photodynamic Therapy 2015/07
22.	Review article	Proposed therapeutic strategy for adult low-grade glioma based on aggressive tumor resection. 2015/01
23.	Original article	Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma. 2014/09
24.	Other	INFORMATION-GUIDED SURGERY USING INTRAOPERATIVE MRI AND FUNCTIONAL MAPPING FOR GLIOMAS 2014/07
25.	Original article	Phase II clinical study on intraoperative photodynamic therapy with talaporfin sodium and semiconductor laser in patients with malignant brain tumors. 2013/10
26.	Review article	Updated therapeutic strategy for adult low-grade glioma stratified by resection and tumor subtype. 2013/07
27.	Review article	Smart Cyber Operating Theater (SCOT) for Endoscopic Surgery Up-to-date Information on Research and Treatment in Endoscopic Surgery(8)Future Perspective on an Endoscope : Smart Cyber Operating Theater (SCOT) for Endoscopic Surgery 2012/12
28.	Review article	Clinical and Practical Investigation for the Intraoperative Examination Monitor for Awake Surgery (IEMAS) as a medical device 2012/10
29.	Original article	Information-Guided surgery of Intracranial Gliomas : Overview of an Advanced intraoperative technology 2012/08
30.	Original article	Clear cells are associated with proliferative activity in ependymoma: a quantitative study 2012/05
31.	Review article	Development of Medical Equipment & Regulatory Science : The Definition of the Evaluation System of the Medical by a Science of a Harmonizing Judgement and a Decision with a Society to have Taken Account of a Cost Performance 2012/05
32.	Review article	Usefulness and Future Aspect of Intraoperative MRI for Neurosurgery 2011/08
33.	Original article	Wireless modification of the intraoperative examination monitor for awake surgery. 2011/06
34.	Case report	Information-guided surgical management of gliomas using low-field-strength intraoperative MRI. 2011/04
35.	Original article	Assessment of effect and toxicity of temozolomide combined with radiation therapy for newly-diagnosed glioblastoma in Japan 2009/12
36.	Review article	The Development of Medical Device and Investigator Initiated Trial 2009/04
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■ Academic conference presentation

1.	Information-guided surgery centered on intraoperative magnetic resonance imaging ensures quality and safety with ultra-low mortality 2022/06/09
2.	Outcomes of information-guided surgery using intraoperative MRI as the core -ensuring the quality and safety of surgery 2022/04/16
3.	Preoperative differential diagnosis of grade II and grade III in cases with astrocytoma, IDH mutant 2021/12/06
4.	Treatment results of information-guided surgery centered on intraoperative MRI that enables both quality and safety 2021/12/06
5.	Investigation of surgical site infection risk factor in glioma surgery 2021/12/05
6.	Long term follow-up clinical results of lower grade gliomas treated with consistent treatment protocol in a single center 2021/12/05
7.	Reviewing of risk factors predicting early death in 1p/19q-dodeleted WHO grade 2, 3 gliomas 2021/12/05
8.	Verification of APT image and relationship with T2/FLAIR mismatch sign in WHO2016 brain tumor pathology classification 2021/12/05
9.	Tert promoter mutation, not H3K27M mutation is a prognostic factor for adult thalamic gliomas 2021/11/18
10.	Tumor recurrence patterns after surgical resection of intracranial low-grade gliomas 2021/11/18
11.	Long term follow-up clinical results of lower grade gliomas treated with consistent treatment protocol in a single center 2021/10/28
12.	USEFULNESS OF AMIDE PROTON TRANSFER IMAGE IN IMAGING DIAGNOSIS OF GLIOMA 2019/12/02
13.	CLINICAL EFFICACY OF AWAKE SURGERY: ANALYSIS OF 335 CASE ON EXTENT OF RESECTION AND SURVIVAL TIME 2019/12/01
14.	CLINICAL RESULT AND CONSIDERATION OF 70 CASES OF INSULAR GLIOMA 2019/12/01
15.	CONTRAST-ENHANCED MRI AND POSITRON EMISSION TOMOGRAPHY FOR DISTINGUISHING THE GRADE OF GLIOMA 2019/12/01
16.	PHASE III RANDOMIZED CLINICAL TRIAL OF AFTV FOR NEWLY DIAGNOSED GLIOBLASTOMA 2019/12/01
17.	PREDICTIVE FACTORS RELATING TO OUTCOME AFTER RESECTION OF LOW-GRADE GLIOMAS WITHOUT CHEMOTHERAPY OR RADIOTHERAPY 2019/12/01
18.	Normalized Brain Datasets with Functional Information Project the Future-predicting Glioma Surgery 2019/09/07
19.	Role of photodynamic therapy using talaporfin sodium and a semiconductor laser in patients with newly diagnosed glioblastoma 2019/07/26
20.	First-in-human Clinical Trial of Sonodynamic Therapy with Drug Delivery System 2018/12/14
21.	Robotized Operating Room : SCOT(Smart Cyber Operating Theater) 2018/04/20
22.	Photodynamic Therapy for malignant brain tumor: clinical trials and results 2017/11/10
23.	Inducing factors of malignant recurrence in low grade glioma 2017/10/14
24.	Inducing factors of malignant recurrence in low grade glioma 2017/10/14
25.	Role of Photodymanic therapy (PDT) using Talaporfin sodium for 30 cases withglioblastomas. 2017/10/14
26.	Treatment outcome of 186 astrocytic tumors comparison between old and new WHOclassification 2017/10/14
27.	impact of 415 awake craniotomy for multidisciplinary integrated glioma surgery 2017/10/13
28.	Malignancy index using intraoperative flowcytometry is a valuable prognostic factorin glioblastomas treated with radiotherapy plus concomitant temozolomide 2017/10/13
29.	Risk factor for communicating hydrocephalus following surgery of newly diagnosedsupratentorial Glioblastoma 2017/10/13
30.	Development of decision-making system by integration of information for artificial-intelligent surger 2017/10/12
31.	Photodynamic Therapy for malignant brain tumor: clinical trials and results 2017/09/02
32.	Photodynamic Therapy for malignant brain tumor: clinical trials and results 2017/07/15
33.	Retrospective volumetric analysis using intraoperative MR imaging for 122 WHO grade III gliomas: Threshold of the extent of resection 2017/06/24
34.	Role of preoperative DTI tractography for surgical management of gliomas 2017/06/24
35.	Clinical evaluations of surgical instruments exchange with robotic scrub nurse system in neurosurgical operating cases 2017/06/22
36.	Prognosis of thalamic glioma with and without H3-K27M mutation in adults: single institutional study 2017/05/20
37.	Re-evaluation of treatment outcome of 186 astrocytic tumors based onthe WHO 2016 classification 2017/05/20
38.	Does a long term temozolomide have a favor effect on long surviving glioblastoma patients? 2017/05/06
39.	Randomized placebo-controlled trial of autologous formalin-fixed tumor vaccine for newly dianosed glioblastoma 2017/05/06
40.	Digitized Brain-mapping and Functional Database for the Future-predicting Glioma Surgery - Progress Overview FY2016- 2017/03/09
41.	Volumetric analysis using low-field intraoperative magnetic resonance imaging for168 newly diagnosed supratentorial glioblastomas: effects of extent of resectionand residual tumor volume on survival and recurrence. 2017/02/24
42.	Sonodynamic therapy using Epirubicin-incorporating drug delivery system and focused ultrasound 2016/11/29
43.	Correspondence of survival curves between conventional and new diagnoses adopted by the 2016 WHO classification in 367 newly diagnosed grade 2/3 glioma at TWMU 2016/11/18
44.	Design optimization for robotic scrub nurse in neurosurgical operations 2016/10/06
45.	PHOTODYNAMIC THERAPY WITH TALAPORFIN SODIUM IN TREATMENT OF MALIGNANT GLIOMA 2016/06/24
46.	Digitized brain-mapping localization and their compiled brain-function database can lead the future-predicting glioma surgery 2016/06/23
47.	Diagnostic capability of [11C]-methionine PET with grade 2/3 newly diagnosed glioma classified in 2016 WHO new classification 2016/06/04
48.	Last-line therapy for malignant glioma using bevacizumab,anti PD-1 and AFTV 2016/06/04
49.	Fabrication of flexible maneuverable laser therapeutic device for photo dynamic therapy (PDT) in malignant brain tumor cases 2016/04/26
50.	Autologous Formalin Fixed Tumor Vaccine for Patients with Newly-Diagnosed Glioblastoma; From Concept to Double Blind Phase IIb/III trial 2016/04/11
51.	Treatment strategy and outcome for insular glioma in one institution 2016/04/09
52.	Digitized Brain-mapping Localization and their Compiled Brain-function Database For the Future-predicting Glioma Surgery -Progress Overview FY2015 2016/02/12
53.	Evaluation of Extensive Resection and Residual tumor volume by Volumetric Analysis Authors 2015/08/21
54.	Good collaboration leads a novel medical devise and therapy 2015/08/21
55.	Preoperative MRI-based delineation of the sulcal and gyral anatomy and its usefulness for glioma resection in neurosurgery 2015/06/27
56.	Clinical result of 132 newly diagnosed glioblastoma based on volumetric analysis with 3D slicer from a single institution 2015/06/25
57.	Penetration depth of the 664-nm semiconductor laser light with talaporfin sodium into human brain tissue with glioma 2015/05/24
58.	Evaluation of Photodynamic Therapy with Talaporfin Sodium on Relapse Controlling Efficacy at Laser Irradiation Sites In Newly Diagnosed Glioblastoma 2015/05/23
59.	Clinical outcome of bevacizumab-treated patients with recurrent malignant gliomas 2014/11/15
60.	Intraoperative flow cytometry analysis of glioma tissue for rapid determination of tumor presence and its histopathological grade 2014/11/15
61.	Factors associated with malignant transformation of low-grade glioma 2014/11/14
62.	Long-term clinical results of extensive tumor removal followed by ACNU-based chemoradiotherapy for 147 anaplastic gliomas 2014/11/14
63.	Impact of the Extent of Surgery on PFS and OS in Patients with Insular Anaplastic (WHO Grade III) Gliomas: Analysis based on Tumor Volumetry 2014/10/13
64.	Phase II clinical study on intraoperative photodynamic therapy in patients with malignant brain tumors 2014/06/29
65.	Updated therapeutic strategy for adult low-grade glioma stratified by resection,histology,and molecular markers 2013/11/22
66.	Nitrosourea based chemotherapy and radiotherapy for grade 2 and 3 gilomas do not affect fertility 2013/11/21
67.	1p/19q LOH analysis using fluorescence in situ hybridization (FISH) is useful for differentiation of astro and oligodendroglial tumors 2013/10/18
68.	Combination therapy using surgery, radiation, temozolomide and autologous tumor vaccine for treatment of patients with initially diagnosed glioblastoma 2013/10/18
69.	First Investigator Initiated Clinical Trial of Combined Products on Photodynamic Therapy with Talaporfin Sodium and Semiconductor Laser in Patients with Malignant Brain Tumors 2013/10/18
70.	IA case of glioma in the left precentral gyrus suspected the involvement of ipsilateral cortical spinal tract 2013/10/18
71.	Intraoperative flow cytometry (iFC) enables differentiation of primary CNS lymphoma from glioblastoma 2013/10/18
72.	The treatment results of awake surgery with language-related functional mapping in 168 glioma cases. 2013/10/18
73.	Multimodal Strategy using Information-guided Surgery and Novel Therapy for Gliomas 2013/10/16
74.	Nitrosourea based chemotherapy and radiotherapy for grade 2 and 3 gliomas do not affect fertility. 2013/10/16
75.	Nursing Consultation by CNS: Redesigning the Social Life of Patients with Neuropsycological Disorder after Glioma Surgery 2013/09/14
76.	Contribution of Language Mapping i Glioma Surgery:Methodology and Functional Considerations in Awake Surgery 2013/09/12
77.	A Phase Two Clinical Study on Photodynamic Therapy (pdt) with Second-generation Photosensitizer Talaporfin Sodium and Semiconductor Laser in Patients with Malignant Brain Tumors 2013/09/09
78.	Extensive Resection of the Low-grade Glioma Based on the Concept of Information-guided Surgery 2013/09/09
79.	Role of Preoperative Functional MRI in Surgical Management of Gliomas 2012/06/18
80.	Clinical trials of the non-touch intraoperative image controllable interface system using KINECT(TM) 2012/06
81.	Advanced Information-guided Surgery of Brain Tumors: Summary of Tokyo Women's Meidcal University Experience 2012/05/27
82.	Administrative Collaboration among Researchers and Companies as "Director-General for Research Stratagem" for Medical Device Production through the Government Project 2012/05
83.	Direct Intuitive Controllable Interface System For Intraoperative Information With Kinekt ^TM Sensor 2012/03/31
84.	SCOT(Smart Cyber Operating Theater)project:Advanced Medical Information Analyzer for guidance of the Surgical Procedures 2011/12/13
85.	Development of Medical Equipment & Regulatory Science- The Definition of the Evaluation System of the Medical by a Science of a Harmonizing Judgement and a Decision with a Society to have Taken Account of a Cost Performance- 2011/11/24
86.	Clinical Trial Center and Medical Instrument Evaluation Center for New Medical Instrument Parmaceutical Affair Approval 2011/08/26
87.	Current Situation And Problems Of Investigator-Initiated Medical Instrument Trials 2011/08/26
88.	Development of the Non-Touch Intraoperative Image Controllable User Interface System for Avoidance of the Pitfalls during Glioma Removung Operation in the Intelligent Operating Theater 2011/08/26
89.	Development of Wireless Intraoperative Examination Monitor for Awake Surgery(IEMAS) for Glioma Resection 2011/08/26
90.	MRI based sulcal pattern analysis for diagnosis and clinical application in neurosurgery 2011/08/26
91.	New Collaboration Framework between Researchers and Administrators in Medical Engineering Field;Tokyo Wemen's Medical University Experience 2011/08/26
92.	Development of the Contactless Air Controller for Avoidance of the Pitfalls in Intraoperative Assisting Systems 2011/06/22
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■ Academic & professional experience

1.	2008/01～2008/03	Tokyo Women's Medical Hospital
2.	1997/04～2004/06	St. Luke's International Hospital Department of Pharmacy Pharmacist