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(最終更新日:2024-11-08 14:17:15)
ハラグチ ユウジ
Haraguchi Yuuji
原口 裕次
所属
医学研究科 医学研究科 (医学部医学科をご参照ください) 先端生命医科学研究所
職種
特任准教授
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著書
1.
部分執筆
Tissue Fabrication and Regeneration by Cell Sheet Technology, Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine 2017/05
2.
部分執筆
細胞シート技術による3次元細胞システム(3次元組織)の構築および移植用セルスクーパの開発「三次元細胞システム設計論、組織工学ライブラリー2」 2016/08/02
3.
部分執筆
Cell Scooper: A Device for the Rapid Transfer of Living Cell Sheet, Hyper Bio Assembler for 3D Cellular Systems 2015/07
4.
部分執筆
Cell Sheet-Based Myocardial Patches, Myocardial Tissue Engineering 2015/01
5.
部分執筆
Cell sheet-based myocardial tissue engineering, Myocardial Tissue Engineering 2015/01
6.
部分執筆
Cell Sheet-Based Tissue Engineering, Myocardial Tissue Engineering 2015/01
7.
部分執筆
Future Developments, Myocardial Tissue Engineering 2015/01
8.
部分執筆
Introduction, Myocardial Tissue Engineering 2015/01
9.
部分執筆
Scaffold-based myocardial tissue engineering, Myocardial tissue engineering 2015/01
10.
部分執筆
Cell sheet technology for cardiac tissue engineering, Methods in Molecular Biology (Cardiac Tissue Engineering) 2014/06
11.
部分執筆
ヒトES/iPS 細胞から心筋細胞への分化誘導法「再生医療における臨床研究と製品開発」 2013/09
12.
部分執筆
再生医療実現のために「再生医療における臨床研究と製品開発」 2013/09
13.
部分執筆
Cell-Based Therapy for Cardiovascular Injury, Emerging Trends in Cell and Gene Therapy 2013/07
14.
部分執筆
Cell sheet nano technology engineering and applications to cardiology, Nanomedicine and the Cardiovascular System 2011/10
5件表示
全件表示(14件)
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学術雑誌
1.
原著
Muscle cell proliferation using water-soluble extract from nitrogen-fixing cyanobacteria Anabaena sp. PCC 7120 for sustainable cultured meat production. 2023/10/04
2.
原著
Proliferation of mammalian cells with Chlorococcum littorale algal compounds without serum support. 2023/10
3.
原著
Circular cell culture for sustainable food production using recombinant lactate-assimilating cyanobacteria that supplies pyruvate and amino acids. 2023/06/16
4.
原著
Development of serum-free and grain-derived-nutrient-free medium using microalga-derived nutrients and mammalian cell-secreted growth factors for sustainable cultured meat production 2023/01/10
5.
原著
Production of scaffold-free cell-based meat using cell sheet technology. 2022/09
6.
原著
Proliferation and differentiation of primary bovine myoblasts using Chlorella vulgaris extract for sustainable production of cultured meat. 2022/03/30
7.
原著
Microalgal culture in animal cell waste medium for sustainable 'cultured food' production. 2021/11
8.
原著
Cell detachment from monolayer- and bilayer-type gold nanoparticle-containing collagen coatings by visible laser irradiation for cell sorting applications 2021/07/13
9.
原著
Three-dimensional tissue fabrication system by co-culture of microalgae and animal cells for production of thicker and healthy cultured food. 2021/03
10.
原著
Mammalian cell cultivation using nutrients extracted from microalgae. 2020/03
11.
原著
Analysis of force vector field during centrifugation for optimizing cell sheet adhesion. 2019/10
12.
原著
Rapid creation system of morphologically and functionally communicative three-dimensional cell-dense tissue by centrifugation. 2018/12
13.
総説
微小流路システムによるiPS細胞由来心筋細胞の可視光照射高速選択剥離/回収技術 2018/08
14.
原著
Contractile force measurement of human induced pluripotent stem cell-derived cardiac cell sheet-tissue 2018/05
15.
総説
藻類と動物細胞の共生リサイクル培養による立体心筋組織の作製 2018/03
16.
原著
Rapid fabrication of detachable three-dimensional tissues by layering of cell sheets with heating centrifuge 2018/01
17.
原著
Real-time quantitation of internal metabolic activity of three-dimensional engineered tissues using an oxygen microelectrode and optical coherence tomography. 2017/05
18.
原著
Optical coherence microscopy of living cells and bioengineered tissue dynamics in high-resolution cross-section. 2017/04
19.
原著
Three-dimensional human cardiac tissue engineered by centrifugation of stacked cell sheets and cross-sectional observation of its synchronous beatings by optical coherence tomography 2017/02
20.
原著
Thicker three-dimensional tissue from a symbiotic recycling system combining mammalian cells and algae 2017/01
21.
総説
OCT技術を用いた三次元細胞シート組織の断層観察 2016/10
22.
原著
In situ cross-linked electrospun fiber scaffold of collagen for fabricating cell-dense muscle tissue 2016/06
23.
原著
Preparation of thermoresponsive nanostructured surfaces for tissue engineering 2016/03
24.
原著
TRPV-1-mediated elimination of residual iPS cells in bioengineered cardiac cell sheet tissues. 2016/02
25.
原著
Electrophysiological analysis of mammalian cells expressing hERG using automated 384-well-patch-clamp 2015/12
26.
原著
Rapid fabrication system for three-dimensional tissues using cell sheet engineering and centrifugation 2015/12
27.
原著
Simple suspension culture system of human iPS cells maintaining their pluripotency for cardiac cell sheet engineering 2015/12
28.
原著
Time Course of Cell Sheet Adhesion to Porcine Heart Tissue after Transplantation 2015/10
29.
原著
Real-time, noninvasive optical coherence tomography of cross-sectional living cell-sheets in vitro and in vivo 2015/08
30.
その他
光干渉断層撮影装置(OCT)を用いた3次元細胞シート組織の非侵襲的観察 2015/07
31.
原著
Noninvasive cross-sectional observation of three-dimensional cell sheet-tissue-fabrication by optical coherence tomography 2015/06
32.
原著
Oxygen consumption of human heart cells in monolayer culture 2014/09
33.
総説
Latest status of the clinical and industrial applications of cell sheet engineering and regenerative medicine 2014/01
34.
原著
Chondrocyte differentiation of human endometrial gland-derived MSCs in layered cell sheets 2013/11
35.
原著
A device for the rapid transfer/transplantation of living cell sheets with the absence of cell damage 2013/08
36.
総説
Cell sheet transplantation for heart tissue repair 2013/08
37.
原著
New isolation system for collecting living cells from tissue 2013/01
38.
原著
Creation of human cardiac cell sheets using pluripotent stem cells 2012/08
39.
原著
Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro 2012/04
40.
総説
Cell Therapy and Tissue Engineering for Cardiovascular Disease 2012/02
41.
総説
Scaffold-free Tissue Engineering Using Cell Sheet Technology 2012/02
42.
原著
Creation of mouse embryonic stem cell-derived cardiac cell sheets. 2011/10
43.
総説
Regenerative therapies using cell sheet-based tissue engineering for cardiac disease 2011/10
44.
原著
Electrical interaction between cardiomyocyte sheets separated by noncardiomyocyte sheets in heterogeneous tissues 2010/06
45.
原著
Design of prevascularized three-dimensional cell-dense tissues using a cell sheet stacking manipulation technology. 2010/05
46.
原著
Development of a new assay system for evaluating the permeability of various substances through three-dimensional tissue 2009/10
47.
総説
Cell sheet engineering for regenerative medicine: From the viewpoint of inflammation 2007/05
48.
原著
Electrical coupling of cardiomyocyte sheets occurs rapidly via functional gap junction formation. 2006/09
49.
総説
細胞シート工学を用いた組織再構築および再生医療への応用 2004
50.
原著
CD4-Dependent and CD4-independent utilization of coreceptors by human immunodeficiency viruses type 2 and simian immunodeficiency viruses 2000/12/05
51.
原著
Infection of mesangial cells with HIV and SIV: identification of GPR1 as a coreceptor 2000/08
52.
原著
Apelin peptides block the entry of human immunodeficiency virus (HIV) 2000/05/04
53.
原著
Inhibition of cell-free human T-cell leukemia virus type 1 infection at a postbinding step by the synthetic peptide derived from an ectodomain of the gp21 transmembrane glycoprotein 1999/11
54.
原著
Inhibition of HIV-1 infection by zinc group metal compounds 1999/09
55.
原著
Heat shock cognate protein 70 is a cell fusion-enhancing factor but not an entry factor for human T-cell lymphotropic virus type I 1999/08/02
56.
原著
Changes in and discrepancies between cell tropisms and coreceptor uses of human immunodeficiency virus type 1 induced by single point mutations at the V3 tip of the env protein 1999/07/05
57.
原著
Isolation and characterization of a monoclonal antibody that inhibits HIV-1 infection 1999/07
58.
原著
Human complement component C1q inhibits the infectivity of cell-free HTLV-I 1998/11
59.
原著
Identification of membrane antigens important for adsorption of human T-cell leukaemia virus type I 1998/11
60.
原著
Identification of the chemokine receptor TER1/CCR8 expressed in brain-derived cells and T cells as a new coreceptor for HIV-1 infection 1998/02
61.
原著
Inhibition of plating of human T cell leukemia virus type I and syncytium-inducing types of human immunodeficiency virus type 1 by polycations 1997/11/20
62.
原著
Different properties of human T-cell leukemia virus type I prepared from 8C cat cells and human cells 1997/04
63.
原著
Synthetic studies on the relationship between anti-HIV activities and micelle forming abilities of various alkylated glycyrrhetinate diglycoside sodium sulfates and related compounds 1996/08
64.
原著
Sulfated colominic acid: an antiviral agent that inhibits the human immunodeficiency virus type 1 in vitro 1996/06
65.
原著
Inhibition of human immunodeficiency virus type 1 infectivity by a new amine bellenamine 1996/03
66.
原著
New bellenamine homologs inhibiting human immunodeficiency virus type I infectivity 1996/01
67.
原著
Detection of neutralizing antibodies against human T-cell leukemia virus type 1 using a cell-free infection system and polymerase chain reaction 1994/11/01
68.
原著
Inhibition of adsorption of human T-cell-leukemia virus type 1 by a plant lectin, wheat-germ agglutinin 1994/01/02
5件表示
全件表示(68件)
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学会発表
1.
Utilization of Anabaena sp. extracts for bioactive substances (口頭発表,一般) 2024/10/10
2.
細胞培養の脱仔牛血清に向けた培養細胞分泌物の利用 (ポスター,一般) 2024/08/29
3.
がん細胞パッチ移植によるin vivoヒト腫瘍モデルの作製技術 (ポスター,一般) 2024/07/11
4.
Potential application of microalgae in cultured medium for sustainable cultured meat production (口頭発表,一般) 2023/10/16
5.
持続可能社会を目指した微細藻類と動物細胞を用いた循環型細胞培養システム (口頭発表,シンポジウム・ワークショップ・パネルディスカッション等) 2023/03/25
6.
A novel culture medium for cultured meat production using microalgae-derived nutrients and mammalian cell-secreted growth factors: Development of serum-free and grain-derived nutrient-free medium (ポスター,一般) 2022/12/07
7.
藻類動物細胞共生リサイクル培養による革新的食料生産法の確立 (口頭発表,シンポジウム・ワークショップ・パネルディスカッション等) 2022/07/06
8.
IVT-mRNAを利用した成長因子を分泌する細胞シートの作製の検討 (口頭発表,一般) 2022/03/18
9.
持続可能社会を目指した微細藻類と動物細胞を用いたリサイクル細胞培養システムの開発 (口頭発表,シンポジウム・ワークショップ・パネルディスカッション等) 2022/03/18
10.
培養肉開発における微細藻類栄養素を用いたサステナブルな培養液 (口頭発表,シンポジウム・ワークショップ・パネルディスカッション等) 2022/03/17
11.
Circular Food Production System Using Symbiotic Algae/Animal Cell (口頭発表,一般) 2021/07/12
12.
藻類と動物細胞の共生リサイクル培養による未来の食料生産技術開発 (ポスター,シンポジウム・ワークショップ・パネルディスカッション等) 2019/12/06
13.
宇宙空間での培養肉生産に向けた藻類抽出液を用いた動物細胞培養 (ポスター,一般) 2019/11/07
14.
Cell Cultivation Using Microalgal Extract for Production of Cultured Meat (口頭発表,一般) 2019/10/07
15.
藻類動物細胞共生リサイクル培養による革新的食料生産法の確立 (口頭発表,シンポジウム・ワークショップ・パネルディスカッション等) 2019/07/31
16.
血管付きヒト心筋組織作製のための新規灌流培養法の検討 (口頭発表,一般) 2019/03/21
17.
IVT-mRNAを利用した目的の成長因子を分泌する細胞シート作製の検討 (口頭発表,一般) 2018/11/12
18.
Contractile Force Measurement of Human iPS Cell-Derived Cardiac Cell Sheet-Tissues and Its Application to In Vitro Drug Testing (ポスター,一般) 2018/09/07
19.
Cell biological analysis of human iPS cell-derived beating cardiomyocytes in vitro and development of visible light-responsive collagen gel for cell purification (ポスター,一般) 2018/09/06
20.
ヒトiPS細胞由来心筋細胞の細胞生物学的解析および選択的回収を目指した可視光応答性培養基材の開発 (口頭発表,一般) 2018/03/23
21.
ヒトiPS心筋シート組織の収縮力測定による機能評価と薬剤応答試験 (口頭発表,一般) 2018/03/23
22.
ヒトiPS細胞由来心筋シート組織の収縮力測定による薬物試験 (ポスター,一般) 2018/02/09
23.
Contractile Force Measurement of Human iPS Cell-Derived Myocardial Sheet for in Vitro Drug Testing (口頭発表,一般) 2016/09/05
24.
Elimination of residual iPS cells in bioengineered cardiac cell sheets by TRPV-1 activation (ポスター,一般) 2016/06/23
25.
遠心力を利用した細胞シート積層法 (口頭発表,一般) 2016/03/18
26.
ヒトiPS細胞由来心筋細胞シートの収縮力測定 (口頭発表,一般) 2016/03/17
27.
オートパッチクランプシステムを用いたヒトiPS細胞由来心筋細胞の電気生理学 (口頭発表) 2015/11/27
28.
Contractile Force Measurement of Human iPS Cell-Derived Myocardial Sheet (ポスター,一般) 2015/09/09
29.
自動パッチクランプシステムを用いたヒトiPS細胞由来心筋細胞の電気生理学的解析 (口頭発表,一般) 2015/03/19
30.
光干渉断層撮影装置を用いた三次元的、経時的、非侵襲的細胞シート観察 (口頭発表,一般) 2014/03/06
31.
光トモグラフィーを使用した、細胞シート非侵襲3次元評価手法の確立 (口頭発表,一般) 2013/10/12
32.
Cell-sheet-based bioengineered human cardiac tissue using pluripotent stem cells for heart repair and disease models (ポスター,一般) 2013/06/12
33.
線維芽細胞の差異におけるES細胞由来心筋シートの機能解析 (口頭発表,一般) 2013/03/23
34.
ヒトiPS細胞の心筋細胞への効率的分化誘導および心筋シートの作製 (口頭発表,一般) 2013/03/21
35.
Cell-sheet-based bioengineered human cardiac tissue using pluripotent stem cells (ポスター,一般) 2012/12/11
36.
Expansion and cardiac differentiation of human iPS cells using a suspension culture system (ポスター,一般) 2012/09/07
37.
ヒトiPS細胞の浮遊培養法および心筋細胞への分化誘導法の検討 (口頭発表,一般) 2012/06/14
38.
細胞シート工学を用いたES/iPS細胞由来心筋組織構築 (口頭発表,シンポジウム・ワークショップ・パネルディスカッション等) 2012/06/12
39.
Creation of Cell Sheet-Based Bioengineered Heart Tissue using ES/iPS Cells-Derived Cardiomyocytes (口頭発表,一般) 2012/03/16
40.
ヒトiPS細胞の浮遊大量培養法の検討 (ポスター,一般) 2011/03/02
41.
間葉系幹細胞シート、骨格筋芽細胞シートより産生されるサイトカイン・ケモカイン量の解析 (口頭発表,一般) 2009/11/17
42.
非心筋細胞シートを挟んだ心筋シート間の電気的相互作用の解析 (口頭発表,一般) 2009/11/14
43.
Electrical interaction between cardiomyocyte sheets separated by noncardiomyocyte sheet in heterogeneous tissues (ポスター,一般) 2009/08/30
44.
細胞シート工学を用いた心筋組織-非心筋組織間の電気生理学的解析 (口頭発表,一般) 2006/09/07
45.
The electrophysiological analyses of layered cardiomyocyte sheets (口頭発表,一般) 2005/07/06
46.
心筋細胞シート間の電気的結合メカニズムの解析 (口頭発表,一般) 2004/11/16
5件表示
全件表示(46件)
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現在の専門分野
生体医工学, 細胞生物学 (キーワード:細胞生物学・組織工学)
■
所属学会
1.
日本再生医療学会
2.
∟ 代議員
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学歴
1.
1991/04~1995/03
群馬大学 博士課程修了 医学博士