教員情報 - 眞部　俊

（最終更新日：2025-12-01 17:10:42）

  マナベ　シユン   MANABE Shiyun
  眞部　俊
   所属   医学部医学科（東京女子医科大学病院）  腎臓内科

職種講師

■ 学術雑誌

1.	原著	Attribute-Based Medicine for IgAN: A Nationwide Japanese Cohort Reveals Prognostic Interactions 2025/10
2.	原著	Challenges in the Histopathologic Diagnosis of Autosomal Dominant Alport Syndrome: A Comparative Genotype-Based Study 2025/10
3.	原著	Disease-Specific Prevalence and Clinical Significance of Antinephrin Autoantibodies in Adult Japanese Patients with Podocytopathy: A Single-Center Cohort Study, 2016-2024 2025/10
4.	原著	Granulomatous Interstitial Nephritis Suspected to Be Caused by Adverse Reaction to Metal Debris: A Case Report 2025/10
5.	原著	High-Pulse Pressure and Kidney Prognosis in ADPKD: Insights from Attribute-Based Cross-Classification by Sex and Age 2025/10
6.	原著	Hypertriglyceridemia and Kidney Prognosis in ADPKD: Insights from Attribute-Based Cross-Classification by Sex and Age 2025/10
7.	原著	Hyperuricemia and Kidney Prognosis in ADPKD: Insights from Attribute-Based Cross-Classification by Sex and Age 2025/10
8.	原著	Increased Risk of Middle Cerebral Artery Aneurysms in Postmenopausal Women with ADPKD: Insights from Attribute-Based Medicine (ABM) with Cross-Classification Based on Sex and Age 2025/10
9.	原著	Attribute-Based Medicine for IgA Nephropathy: Risk Factor Constellations Influence Kidney Prognosis. 2025/08/27
10.	原著	Middle cerebral artery aneurysms in older women with autosomal dominant polycystic kidney disease. 2025/05/31
11.	原著	Overexpression of plasmalemmal vesicle-associated protein-1 in patient with cyanotic nephropathy: a case report. 2025/03
12.	原著	常染色体顕性(優性)多発性嚢胞腎におけるSplicing mutationと脳動脈瘤発症の関連性について 2025/03
13.	原著	Association of hyperphosphatemia with renal prognosis in patients with autosomal dominant polycystic kidney disease. 2025/01
14.	原著	Urinary casts containing crystals in light chain proximal tubulopathy. 2024/11
15.	原著	腎生検所見から何を学ぶか(No.67)　急激な腎機能障害,心機能障害を呈しcrystalglobulin-induced nephrologyが疑われた1例 2024/10/25
16.	原著	Protocol for the nationwide registry of patients with polycystic kidney disease: japanese national registry of PKD (JRP) 2024/10
17.	症例報告	30年の長期寛解後に再発したC3腎炎の一例 2024/09/10
18.	原著	リツキシマブを使用した膜性腎症 2024/09/10
19.	症例報告	感染後糸球体腎炎(PIGN)を発症した腎移植ドナーの2症例 2024/09/10
20.	症例報告	血管炎を呈した薬剤性尿細管間質性腎炎の1例 2024/09/10
21.	症例報告	高安動脈炎,腎動脈狭窄によるFSGSに経皮的腎動脈形成術(PTRA)が著効した一例 2024/09/10
22.	症例報告	腎生検でIgG-κ産生B細胞性リンパ腫を診断したCrystal storing histiocytosis(CSH)の一例 2024/09/10
23.	症例報告	致死的な経過をたどったCrystalglobulin-induced nephropathyの一例 2024/09/10
24.	症例報告	長期関節リウマチ患者に発症したNELL-1陽性の抗DNA抗体陰性ループス腎炎の1例 2024/09/10
25.	症例報告	尿沈渣が診断に有用であったLight chain proximal tubulopathy(LCPT)の3例 2024/09/10
26.	原著	IgA腎症における属性医療(ABM)～性差,年齢,BMI,CKD-stageの腎予後因子への影響について 2024/06/15
27.	原著	常染色体顕性多発性嚢胞腎における脳動脈瘤と脳出血の有病率と特徴 2024/06/15
28.	原著	ADPKD患者の脳動脈瘤に関する性差について 2024/06
29.	原著	Immediate drop of urine osmolality upon tolvaptan initiation predicts impact on renal prognosis in patients with ADPKD 2024/05/31
30.	症例報告	胆管交通性感染肝嚢胞に対して胆管バルーン併用硬化療法で感染制御，瘻孔閉鎖できた一例 2024/05/28
31.	原著	Factors associated with early-onset intracranial aneurysms in patients with autosomal dominant polycystic kidney disease. 2024/05
32.	原著	常染色体顕性(優性)多発性嚢胞腎におけるSplicing mutationと脳動脈瘤発症の関連性について 2024/03
33.	原著	【ガイドライン改訂で変わる　糖尿病関連腎臓病(DKD)診療】(第2章)糖尿病関連腎臓病の治療　生活習慣と自己管理　生活習慣と運動療法 2024/02/25
34.	原著	Factors associated with early-onset intracranial aneurysms in patients with autosomal dominant polycystic kidney disease 2024/02/05
35.	原著	Correction to: Public support for patients with intractable diseases in Japan: impact on clinical indicators from nationwide registries in patients with autosomal dominant polycystic kidney disease 2024/01
36.	原著	Immediate drop of urine osmolality upon tolvaptan initiation predicts impact on renal prognosis in patients with ADPKD. 2023/11/03
37.	原著	Public support for patients with intractable diseases in Japan: impact on clinical indicators from nationwide registries in patients with autosomal dominant polycystic kidney disease. 2023/10
38.	原著	肺動静脈瘻コイル塞栓後の再開通により低酸素血症をきたしていた一例 2023/05
39.	総説	【もっと知ろう透析患者の栄養と身体評価】フレイルの評価 2023/04
40.	総説	Cystic Kidney Diseases That Require a Differential Diagnosis from Autosomal Dominant Polycystic Kidney Disease (ADPKD). 2022/11
41.	原著	Machine learning for morbid glomerular hypertrophy. 2022/11
42.	原著	Initial decline in eGFR to predict tolvaptan response in autosomal-dominant polycystic kidney disease. 2022/06
43.	原著	Mutation Type and Intracranial Aneurysm Formation in Autosomal Dominant Polystic Kidney Disease 2022/05/20
44.	原著	Slowly Progressive Male Alport Syndrome Evaluated by Serial Biopsy: Importance of Type IV Collagen Staining. 2022/04
45.	原著	Initial decline in eGFR to predict tolvaptan response in autosomal-dominant polycystic kidney disease 2022/01/29
46.	原著	Correction to: Pleiotropic effect of erythropoiesis‑stimulating agents on circulating endothelial progenitor cells in dialysis patients. 2022/01
47.	原著	Germline Mutations for Kidney Volume in ADPKD 2021/12/13
48.	総説	ADPKD 3）遺伝子診断：診断と予後 2021/11
49.	原著	Slowly Progressive Male Alport Syndrome Evaluated by Serial Biopsy:Importance of Type ⅣCollagen 2021/10/12
50.	原著	Urinary Aquaporin 2 as a Potential Indicator Predicting Tolvaptan Response in Patients With ADPKD 2021/07/14
51.	原著	Dose-Dependent Effect of Tolvaptan on Renal Prognosis in Patients with Autosomal Dominant Polycystic Kidney Disease 2021/07
52.	原著	Renal amyloidosis with monotypic IgM lambda deposition 2021/07
53.	原著	Renal amyloidosis with monotypic IgM lambda deposition 2021/06/19
54.	原著	Pleiotropic effect of erythropoiesis-stimulating agents on circulating endothelial progenitor cells in dialysis patients 2021/06/09
55.	原著	Lupus Nephritis and Hydroxychloroquine-Associated Zebra Bodies: Not Just in Fabry Disease 2021/05/18
56.	原著	Predicting liver cyst severity by mutations in patients with autosomal-dominant polycystic kidney disease 2021/04/02
57.	原著	The origin of urinary mulberry cells in Fabry 2021/04
58.	原著	Impact of visceral fat area in patients with chronic kidney desease 2021/02/17
59.	原著	Everolimus-associated focal segmental glomerulosclerosis in a liver transplant recipient 2020/12/09
60.	原著	Cell invasion in glomerular basement membrane: infolding glomerulopathy 2020/12/06
61.	原著	Sex Differences in Time-Series Changes in Pseudo-R²　Values Regarding Hyperuricemia in Relation to the Kidney Prognosis 2020/11/26
62.	原著	Visceral to subcutaneous fat ratio as an indicator of a ≧30％　eGFR decline in chronic kidney disease 2020/11
63.	原著	Maximum Carotid Intima-Media Thickness in Association with Renal Outcomes 2020/08
64.	原著	A standardized protocol for the mulberry cells and mulberry bodies in the urinary sediment of Fabry disease 2020/07/11
65.	原著	Time series changes in pseudo-R2 values regarding maximum glomerular diameter and the Oxford MEST-C score in patients with IgA nephropathy: A long-term follow-up study. 2020/05/07
66.	原著	Urinary Mulberry Cells as a Biomarker of the Efficacy of Enzyme Replacement Therapy for Fabry Disease. 2020/04
67.	原著	High Serum Phosphate Level as a Risk Factor to Determine Renal Prognosis in Autosomal Dominant Polycystic Kidney Disease: A Retrospective Study 2020/03/10
68.	原著	Association between anemia and renal prognosis in autosomal dominant polycystic kidney disease: a retrospective study. 2020/02/08
69.	原著	Prediction of Renal Prognosis in Patients with Autosomal Dominant Polycystic Kidney Disease Using PKD1/PKD2 Mutations. 2020/01/05
70.	原著	Impacts of Sex Differences in Pulse Pressure among Patients with Chronic Kidney Disease. 2019/12/09
71.	原著	Low HDL cholesterol as a predictor of chronic kidney disease progression: a cross-classification approach and matched cohort analysis. 2019/09
72.	原著	Primary IgA Vasculitis with Nephritis in a Patient with Rheumatoid Arthritis Diagnosed by Antigalactose-deficient IgA1 Immunostaining. 2019/09
73.	原著	A Case of Primary IgA Vasculitis with Nephritis in a Patient with Rheumatoid Arthritis Diagnosed by Anti-galactose-deficient IgA1 Immunostaining. 2019/06
74.	原著	Low HDL cholesterol as a predictor of chronic kidney disease progression:a cross-classification approach and matched cohort analysis. 2019/03
75.	原著	Successful entecavir plus prednisolone treatment for hepatitis B virus-associated membranoproliferative glomerulonephritis:A case report. 2019/01
76.	原著	【病因、病態、病理学】APOL1 腎症 2018/12
77.	原著	Comparison of the response of frequently relapsing steroid-dependent minimal change nephrotic syndrome to retuximab therapy between childhood-onset and adult-onset disease. 2018/10
78.	原著	AL amyloidosis with non-amyloid forming monoclonal immunoglobulin deposition;a case mimicking AHL amyloidosis. 2018/09
79.	原著	Direct Effects of Immunomodulatory Agents on Podocytes in Immune-Mediated Glomerular Diseases. 2018/05
80.	原著	Myeloperoxidase-antineutrophil cytoplasmic antibody causes different renal diseases by immune-complex formation and pauci-immune mechanism:A case report. 2017/08
81.	原著	Myeloperoxidase-antinertrophil cytoplasmic antibody causes defferent renal diseases by immunecomplex formation and pauci-immune mechanism:A case report 2017/06
82.	原著	A case of PR3-ANCA-positive anti-GBM disease associated with intrarenal arteritis and thrombotic microangiopathy. 2017/05
83.	原著	A case of PR3-ANCA-positive anti-GBM disease associated wuth intrarenal arteritis and thrombotic microangiopathy. 2017/05
84.	症例報告	腎疾患の最終診断としての病理、質量分析、遺伝子診断　質量分析の腎疾患病態解明と最終診断への貢献 2017/04
85.	総説	【糸球体腎炎】糸球体腎炎発症の免疫学的多様性 2016/07
86.	原著	Renal AH Amyloidosis Associated With a Truncated Immunoglobulin Heavy Chain Undetectable by Immunostaining. 2015/12
87.	原著	Renal AH Amyloidosis Associated With a Truncated Immunoglobulin Heavy Chain Undetectable by Immunostaining 2015/09
88.	原著	Bucillamine-induced membranous nephropathy with crescent formation in a patient with rheumatoid arthritis: case report and literature review. 2015/07
89.	総説	【腎と免疫】質量分析(mass spectrometry)の腎疾患への適応 2015/05
90.	総説	質量分析（mass spectrometry)の腎疾患への適応 2015/05
91.	症例報告	Bucillamine-Induced Membranous Nephropathy with Crescent Formation in a Patient with Rheumatoid Arthritis 2014/10
92.	原著	Renal Infarction in a Patient with Pulmonary Vein Thrombosis after Left Upper Lobectomy 2014/05
93.	症例報告	出産を契機に顕性化した妊娠関連非典型溶血性尿毒症症候群の1例 2014/01
94.	症例報告	IgG4-Related Tubulointerstitial Nephritis and Lymphadenopathy after Therapy for Malignant Lymphoma. 2012/05
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■ 学会発表

1.	多発性嚢胞腎における腹膜透析導入患者の治療成績と離脱要因の検討（Speech，General） 2025/12/07
2.	Granulomatous Interstitial Nephritis Suspected to Be Caused by Adverse Reaction to Metal Debris: A Case Report （Poster notice，General） 2025/11/08
3.	Hypertriglyceridemia and Kidney Prognosis in ADPKD: Insights from Attribute-Based Cross-Classification by Sex and Age （Poster notice，General） 2025/11/08
4.	Hyperuricemia and Kidney Prognosis in ADPKD: Insights from Attribute-Based Cross-Classification by Sex and Age （Poster notice，General） 2025/11/08
5.	Attribute-Based Medicine for IgAN: A Nationwide Japanese Cohort Reveals Prognostic Interactions （Poster notice，General） 2025/11/07
6.	High-Pulse Pressure and Kidney Prognosis in ADPKD: Insights from Attribute-Based Cross-Classification by Sex and Age （Poster notice，General） 2025/11/07
7.	Challenges in the Histopathologic Diagnosis of Autosomal Dominant Alport Syndrome: A Comparative Genotype-Based Study （Poster notice，General） 2025/11/06
8.	Disease-Specific Prevalence and Clinical Significance of Antinephrin Autoantibodies in Adult Japanese Patients with Podocytopathy: A Single-Center Cohort Study, 2016-2024 （Poster notice，General） 2025/11/06
9.	Increased Risk of Middle Cerebral Artery Aneurysms in Postmenopausal Women with ADPKD: Insights from Attribute-Based Medicine (ABM) with Cross-Classification Based on Sex and Age （Poster notice，General） 2025/11/06
10.	透析前随時血糖値と糖尿病を合併した維持血液透析患者の死亡率の関連～日本透析医学会統計調査の検討～（Speech，General） 2025/06/27
11.	ARNIによるSGLT2阻害薬のinitial dip抑制効果の検討（Speech） 2025/06/21
12.	SLE患者におけるヒドロキシクロロキン使用に伴うゼブラボディ/ミエロイドボディ出現の検討（Speech） 2025/06/21
13.	ADPKD患者における腎予後に関する性差～属性に基づく医療（ABM）の視点より（Speech） 2025/06/20
14.	結節性・分節性硬化性病変への臨床的な考え方（Speech） 2025/06/20
15.	微小変化型ネフローゼ症候群に対するリツキシマブ療法（Speech） 2025/06/20
16.	Sex Differences and Aging Influence the Association between Kidney Prognosis and Intracranial Aneurysms in Patients with ADPKD: Attribute-Based Medicine (ABM) Insights （Poster notice，General） 2024/10/26
17.	Sex- and Age-Related Variations in Intracranial Aneurysms among Patients with ADPKD: Significance of Middle Cerebral Artery Aneurysms in Elderly Women （Poster notice，General） 2024/10/26
18.	Decreased risk of dialysis-related amyloidosis in the 2010s: Results from Japanese nationwide surveys in 2010 and 2017 （Poster notice，General） 2024/10/25
19.	Diagnostic Utility of Urinary Sediments in Light-Chain Proximal Tubulopathy (LCPT): Report of Three Cases （Poster notice，General） 2024/10/25
20.	Hydroxychloroquine (HCQ)-Associated Zebra and Myeloid Bodies in Patients with Systemic Lupus Erythematosus (SLE) （Poster notice，General） 2024/10/25
21.	Overweight/Obesity and Pulse Pressure: Kidney Prognosis in Young and Elderly Patients with ADPKD Regarding Attribute-Based Medicine (ABM) Insights （Poster notice，General） 2024/10/25
22.	Predialysis Causal Blood Glucose Level and Mortality in Diabetic Patients on Hemodialysis: A Nationwide Cohort Study from Japan （Poster notice，General） 2024/10/25
23.	Sex Differences in Kidney Prognosis in Patients with ADPKD: Attribute-Based Medicine (ABM) Insights （Speech） 2024/10/25
24.	Association of Anemia (Hemoglobin <13 g/dL in Men and <12 g/dL in Women) with Long-Term Kidney Prognosis in Patients with ADPKD: Insights from Time Series Analyses （Poster notice，General） 2024/10/24
25.	Reduced Flippase Activity in the Early Life of Mature Erythrocytes Is Associated with Their Shortened Lifespan in Renal Anemia （Poster notice，General） 2024/10/24
26.	Sex and Aging Influence the Association between Kidney Prognosis and Anemia in Patients with ADPKD: Attribute-Based Medicine (ABM) Insights （Poster notice，General） 2024/10/24
27.	生体ドナーが腎提供後にANCA関連血管炎による腎機能障害をきたした1例（Speech，General） 2024/10/05
28.	30年の長期寛解後に再発したC3腎炎の一例（Speech，General） 2024/09/29
29.	感染後糸球体腎炎(PIGN)を発症した腎移植ドナーの2症例（Poster notice，General） 2024/09/29
30.	血管炎を呈した薬剤性尿細管間質性腎炎の1例（Poster notice，General） 2024/09/29
31.	高安動脈炎,腎動脈狭窄によるFSGSに経皮的腎動脈形成術(PTRA)が著効した一例（Speech，General） 2024/09/29
32.	常染色体優性アルポート症候群およびADPKD-IFT140と診断した高齢男性の一例（Speech，General） 2024/09/29
33.	致死的な経過をたどったCrystalglobulin-induced nephropathyの一例（Speech，General） 2024/09/29
34.	尿沈渣が診断に有用であったLight chain proximal tubulopathy(LCPT)の3例（Speech，General） 2024/09/29
35.	リツキシマブを使用した膜性腎症（Speech，General） 2024/09/28
36.	腎生検でIgG-κ産生B細胞性リンパ腫を診断したCrystal storing histiocytosis(CSH)の一例（Speech，General） 2024/09/28
37.	長期関節リウマチ患者に発症したNELL-1陽性の抗DNA抗体陰性ループス腎炎の1例（Speech，General） 2024/09/28
38.	ADPKD患者の脳動脈瘤に関する性差について（Poster notice，General） 2024/06/30
39.	常染色体顕性多発性嚢胞腎における脳動脈瘤と脳出血の有病率と特徴（Speech，General） 2024/06/30
40.	IgA腎症における属性医療(ABM)～性差,年齢,BMI,CKD-stageの腎予後因子への影響について（Speech，General） 2024/06/28
41.	胆管交通性感染肝嚢胞に対して胆管バルーン併用硬化療法で感染制御,瘻孔閉鎖できた一例（Speech，General） 2024/06/07
42.	Acute kidney injury and erythema multiforme associated with Helicobacter pylori eradication therapy:Not invariably drug allergy. （Poster notice，Panelist at Symposium/Workshop (Applied)） 2023/11/04
43.	Prevalence and characteristics of intracranial aneurysms and cerebral hemorrhage in patients with autosomal dominant polycystic kidney disease in the Japanese nationwide database （Poster notice，Panelist at Symposium/Workshop (Applied)） 2023/11/04
44.	ADCK4 nephropathy in identical siblings （Poster notice，Panelist at Symposium/Workshop (Applied)） 2023/11/02
45.	ADCK4 変異による COQ10 腎症の一卵性双生児（Speech，General） 2023/09/16
46.	ヘリコバクター・ピロリ過敏症により多型紅斑,急性腎障害をきたした一例（Speech，General） 2023/09/16
47.	肺動静脈瘻コイル塞栓後の再開通により低酸素血症をきたしていた一例（Poster notice，General） 2023/06/17
48.	高度蛋白尿を契機にNPHS1変異を診断された42歳男性（Poster notice） 2022/06
49.	どのように嚢胞感染を疑いどのように治療するか（Speech，Panelist at Symposium/Workshop (Applied)） 2020/11/02
50.	妊娠中に初めて診断された潰瘍性大腸炎に対しGCAP療法を行った1例（Speech，Panelist at Symposium/Workshop (Applied)） 2020/11/02
51.	抗菌薬加療により早期寛解にいたった梅毒関連膜性腎症の1例（Speech，Panelist at Symposium/Workshop (Applied)） 2020/09/26
52.	電顕連続切片にて基底膜内の細胞突起伸展像を評価したpodocyte infolding glomerulopathy(PIG)の1例（Speech，Panelist at Symposium/Workshop (Applied)） 2020/09/26
53.	機械学習法を用いたADPKD患者の遺伝子変異と腎予後についての検討（Speech，Panelist at Symposium/Workshop (Applied)） 2020/08/19
54.	組織学的PLA2R陽性、陰性膜性腎症の臨床病理学的検討（Poster notice，General） 2020/08/19
55.	多発性嚢胞腎に対するトルバプタン治療における尿中アクアポリン2の検討（Speech，Panelist at Symposium/Workshop (Applied)） 2020/08/19
56.	トルバプタン最高用量の服用により腎機能の低下抑制が予測された常染色体優性多発性嚢胞腎の2例（Speech，Panelist at Symposium/Workshop (Applied)） 2019/10/05
57.	Soluble form of VCAM-1 ameliorates podocyte injury by plasma membrane PTEN recruitment （Poster notice，Panelist at Symposium/Workshop (Applied)） 2018/10/26
58.	腎限局性サルコイドーシスによる肉芽腫性間質性腎炎に、ステロイドが奏功した一例（Poster notice，Panelist at Symposium/Workshop (Other)） 2018/10/21
59.	可溶性VCAM-1産生はポドサイト内因性の障害適応機構である（Speech，General） 2018/06/09
60.	Soluble form of VCAM-1 ameliorates podocyte injury by plasma membrane PTEN recruitment. （Poster notice，General） 2018/02/22
61.	Soluble Form of VCAM-1 Ameliorates Podocyte Phenotypic Change by Plasma Membrane PTEN Recruitment （Poster notice，General） 2017/11/02
62.	2種類の質量分析(MS/MS)を用いたAHLとALアミロイドーシスの鑑別（Speech，General） 2017/10/28
63.	高トリグリセリド（TG)血症による重症急性膵炎（SAP)に対する発症早期の血漿交換療法（PE)の有効性（General） 2010/11
64.	腎生検にて糸球体係蹄内に限局して腫瘍細胞を認めたDiffuse Large B-cell Lymphoma(DLBCL)の一例（Speech，General） 2010/09
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■ 学歴

2001/04～2007/03

北海道大学医学部卒業医学士