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 八千代医療センター 病理診断科
Summary Research grants & projects Published papers
Books Academic conference presentation


Professor:

   HIROSHIMA Kenzo
Assistant Professor:
   KAWAMURA Shunji
■ Summary
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■ Research grants & projects
1.  
 Budget amount:\5,000,000  (Co-investigator)
2.  
 Budget amount:\3,000,000  (Co-investigator)
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
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■ Published papers
Original article
1. Tagawa M, Tada Y, Shimada H, Hiroshima K:  Gene therapy for malignant mesothelioma: Current prospects and challenges.  Cancer gene therapy  20 (3) :150-156 , 2013.3   DOI:10.1038/cgt.2013.1
2. Okamoto S, Jiang Y, Kawamura K, Shingyoji M, Fukamachi T, Tada Y, Takiguchi Y, Tatsumi K, Shimada H, Hiroshima K, Kobayashi H, Tagawa M.:  Zoledronic acid produces combinatory anti-tumor effects with cisplatin on mesothelioma by increasing p53 expression levels.  PLos One  8 (3) :e60297 , 2013.3
3. Wu D, Hiroshima K*, Matsumoto S, Nabeshima K, Yusa T, Ozaki D, Fujino M, Yamakawa H, Nakatani Y, Tada Y, Shimada H, Tagawa M:  Diagnostic usefulness of p16/CDKN2A FISH in distinguishing between sarcomatoid mesothelioma and fibrous pleuritis.  American journal of clinical pathology  139 (1) :39-46 , 2013.1   DOI:10.1309/AJCPT94JVWIHBKRD
4. Yamanaka M, Tada Y, Kawamura K, Li Q, Okamoto S, Chai K, Yokoi S, Liang M, Fukamachi T, Kobayashi H, Yamaguchi N, Kitamura A, Shimada H, Hiroshima K, Takiguchi Y, Tatsumi K, Tagawa M.:  E1B-55 kDa-Defective Adenoviruses Activate p53 in Mesothelioma and Enhance Cytotoxicity of Anticancer Agents.  Journal of Thoracic Oncology  7 (12) :1850-1857 , 2012.12
5. Kitamura A, Takiguchi Y, Kurosu K, Takigawa N, Saegusa F, Hiroshima K, Nakajima T, Tanabe N, Nakatani Y, Yoshino I, Tatsumi K:  Feasibility of cytological diagnosis of sarcoidosis with endobronchial US-guided transbronchial aspiration.  Sarcoidosis, vasculitis, and diffuse lung diseases  29 (2) :82-9 , 2012.10
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Review article
1. Tada Y, Shimada H, Hiroshima K, Tagawa M.:  A potential therpeutic strategy for malignant mesothelioma with gene medicine.  BioMed Research International  2013 (Article ID 572609) :8 , 2013.1
2. 中野雅行*:  【肝内胆管癌と細胆管細胞癌】 総論 細胆管細胞癌、幹細胞との関連.  外科  74 (11) :1152-1156 , 2012.11
3. 長谷川瑞江, 酒井文和, 廣島健三:  新たな肺腺癌の分類と画像診断に必要な病理学的知識 細気管支肺胞上皮癌のゆくえ.  呼吸器内科  22 (4) :341-347 , 2012
Case report
1. 藤原 大樹, 石橋 史博, 高橋 好行, 飯田 智彦, 柴 光年, 廣島 健三:  先行する子宮腺筋腫術後出現した多発肺結節に対し手術を施行した1例.  肺癌  53 (1) :64-68 , 2013.2
2. 越智文美, 大坪茂, 武井卓, 内田啓子, 湯村和子, 河村俊治, 秋葉隆, 新田孝作*:  肉芽腫病変を認めた抗糸球体基底膜抗体腎炎の1例.  腎と透析  73 (4) :595-606 , 2012.10
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■ Books
1. 廣島健三:  胸膜の正常構築,正常中皮細胞.  胸膜全書  16-23.  医薬ジャーナル社,  大阪, 2013.3
2. Yukio Nakatani, KenzoHiroshima, Eugene J.Mark:  Sarcomatoid carcinoma and variants.  Spencer's Pathology of the Lung  1186-1223.  Cambridge University Press,  U.K., 2013.1
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■ Academic conference presentation
1. ◎Kenzo Hiroshima, Di Wu, Kazuki Nabeshima, Toshikazu Yusa, Daisuke Ozaki, Yukio Nakatani, Toshiro Nishikawa: Diagnostic Utility of p16 FISH in Distinguishing between Biphasic Mesothelioma and Epithelioid Mesothelioma.  The United States & Canadian Academy of Pathology's 102nd Annual Meeting,  Baltimore, USA,  2013/03
2. ◎T Kawai, S Hiroi, S Ogata, K Nakanishi, K Hiroshima, T Shinagawa, S Shimizu: Peritoneal Malignant Mesothelioma (PMM), Papillary Serous Adenocarcinoma (PSA), and Reactive Mesothelial Hyperplasia (RMH) of the Peritoneum. An Immunohistochemical and
Fluorescence In Situ Hybridization (FISH) Analysis.  The United States & Canadian Academy of Pathology's 102nd Annual Meeting,  Baltimore, USA,  2013/03
3. ◎Kenzo Hiroshima, Di Wu, Shinji Matsumoto, Kazuki Nabeshima, Toshikazu Yusa, Daisuke Ozaki, Michio Fujino, Yukio Nakatani: Diagnostic utility of p16 FISH in distinguishing between sarcomatoid mesothelioma and fibrous pleuritis.  5th Asia Pacific Lung Cancer Conference,  Fukuoka,  2012/11
4. ◎KAWAMURA Shunji, HOSHII Yoshinobu,NISHIKAWA Toshio, UTO Kenta, SEKIGUCHI Morie: Histologic and immunohistochemical studies for the endomyocardial biopsy diagnosis of cardiac amyloidosis in Japanese patients.  5th Biennial Meeting of the Association for European Cardiovascular Pathology (AECVP),  Cadiz, Spain,  2012/10
5. ◎Yuji Tada, Quanhai Li, Kiyoko Kawamura, Hiroshi Kobayashi, Ikuo Sekine, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa: ZOLEDRONIC ACID, THE THIRD GENERATION OF BISPHOSPHONATES, PRODUCES ANTI-TUMOR EFFECTS ON MESOTHELIOMA IN VITRO AND IN VIVO THROUGH APOPTOSIS OR S PHASE ARREST IN P53-INDEPENDENT AND RAS PRENYLATION-INDEPENDENT MANNERS.  11th International Conference of the International Mesothelioma Interest Group,  Boston, U.S.A.,  2012/09
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