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 先端生命医科学研究所
Summary Research grants & projects Awards & honors
Social activities Published papers Books
Academic conference presentation


Professor:
   ARUGA Atsushi
   SHIMIZU Tatsuya
   MURAGAKI Yoshihiro
   YAMATO Masayuki
   MASAMUNE Ken
   ジヤン レジス
   バエ ハン
Associate Professor:
   岩田 隆紀
   Matsuura Katsuhisa
   KOBAYASHI Etsuko
Lecturer:
   Akiyama Yoshikatsu
   KOBAYASHI Jun
   Sekine Hidekazu
   TAKAHASHI Hironobu
   NAKAYAMA Masamichi
   OKAMOTO Jun
   CHERNOV Mikhail
   Haraguchi Yuji
   Kaoru Washio
Assistant Professor:
   Tetsutaro Kikuchi
   Sekiya Sachiko
   Takagi Ryo
   Shinako Masuda
   Homma Jun
   生田 聡子
   KUSUDA Kaori
   KONISHI Yoshiyuki
   Sasaki Daisuke
   NIKI Chiharu

   HORISE Yuki
   MAEDA Masanori
■ Summary
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■ Research grants & projects
1.    (Grant No.:18he0702249h0005)
 Budget amount:\96,684,338  (代表)
2.    (Grant No.:18be0204439h0005)
 Budget amount:\20,000,000  (分担)
3.  
 Budget amount:\975,000  (分担)
4.    (Grant No.:18he0202263h0005)
 Budget amount:\208,875,400  (代表)
5.    (Grant No.:18he1602003h0002)
 Budget amount:\28,004,100  (代表)
6.    (Grant No.:SSU外49-859-戦49)
 Budget amount:\15,569,024  (代表)
7.    (Grant No.:18he1802002h0902)
 Budget amount:\1,300,000  (分担)
8.    (Grant No.:18im0302706h0005)
 Budget amount:\75,500,000  (分担)
9.  
 Budget amount:\3,167,300  (代表)
10.    (Grant No.:18bm0804010h0102)
 Budget amount:\17,000,000  (分担)
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■ Awards & honors
1.  KUSUDA Kaori 22nd Annual Conference of the International Society for Computer, ISCAS-CARS Best Poster Award
2.  Teruo Okano 5th TERMIS World Congress 2018, 2018 TERMIS-AP Excellence Achievement Award
3.  Yusuke Tobe 5th TERMIS World Congress 2018, TERMIS-WC 2018 SYIS Oral Presentation Award 2nd Place
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■ Social activities
1.   Phronesis 19 p102-103
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
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 17 2 8 20 25 45  0 17 0 2  63 107  35 22  13 10
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■ Published papers
Original article
1. SAITO Taiichi, MURAGAKI Yoshihiro, TAMURA Manabu, MARUYAMA Takashi, NITTA Masayuki, TSUZUKI SHUNSUKE, FUKUCHI Satoko, OHASHI Mana, KAWAMATA Takakazu:  Awake craniotomy with transcortical motor evoked potential monitoring for resection of gliomas in the precentral gyrus: utility for predicting motor function.  Journal of neurosurgery  [Epub ahead of print] (**) :e1-e11 , 2019.3
2. Ebata Ryota*, Yasukawa Kumi, Nagai Kazue, Saito Yuko, Higashi Kouji, Homma Jun, Takada Nobuyuki, Takechi Fumie, Saito Naoki, Kobayashi Hironobu, Okunushi Kentaro, Hamada Hiromichi, Kohno Yoichi, Hanaoka Hideki, Shimojo Naoki:  Sivelestat Sodium Hydrate Treatment for refractory Kawasaki Disease Patients.  Pediatrics international : official journal of the Japan Pediatric Society  doi: 10.1111/ped.13851. :Epub , 2019.3
3. Izumu Hosoi, Etsuko Kobayashi, Song Ho Chang, Takumi Matsumoto, Qi An, Emi Anzai, Yuji Ohta, Ichiro Sakumai:  Development of intraoperative plantar pressure measuring system considering weight bearing axis.  International Journal of Computer Assisted Radiology and Surgery  14 (2) :385-395 , 2019.2
4. GOMEZ-TAMES Jose, HIRATA Akimasa, TAMURA Manabu, MURAGAKI Yoshihiro:  Corticomotoneuronal Model for Intraoperative Neurophysiological Monitoring During Direct Brain Stimulation.  International journal of neural systems  29 (1) :1850026 , 2019.2
5. HORI Hiroki, YAMAGUCHI Toshio, KONISHI Yoshiyuki, TAIRA Takaomi, MURAGAKI Yoshihiro:  Correlation between fractional anisotropy changes in the targeted ventral intermediate nucleus and clinical outcome after transcranial MR-guided focused ultrasound thalamotomy for essential tremor: results of a pilot study.  Journal of neurosurgery  [Epub ahead of print] :e1-e6 , 2019.2
6. RYU Bikei, SEKINE Hidekazu, HOMMA Jun, KOBAYASHI Tomonori, KAWAMATA Takakazu, SHIMIZU Tatsuya:  Allogeneic adipose-derived mesenchymal stem cell sheet that produces neurological improvement with angiogenesis and neurogenesis in a rat stroke model.  Journal of neurosurgery  :Epub ahead of print , 2019.2
7. OKA Masatoshi, SEKIYA Sachiko, SAKIYAMA Ryoichi, SHIMIZU Tatsuya*, NITTA Kosaku:  Hepatocyte Growth Factor-Secreting Mesothelial Cell Sheets Suppress Progressive Fibrosis in a Rat Model of CKD.  Journal of the American Society of Nephrology : JASN  30 (2) :261-276 , 2019.2
8. SATO Masato*, YAMATO Masayuki, MITANI Genya, TAKAGAKI Tomonori, HAMAHASHI Kosuke, NAKAMURA Yoshihiko, ISHIHARA Miya, MATOBA Ryo, KOBAYASHI Hiroyuki, OKANO Teruo, MOCHIDA Joji, WATANABE Masahiko:  Combined surgery and chondrocyte cell-sheet transplantation improves clinical and structural outcomes in knee osteoarthritis.  NPJ Regenerative medicine  4 :4 , 2019.2
9. ISHIDA Masaru, MIYAGAWA Shigeru, SAITO Atsuhiro, FUKUSHIMA Satsuki, HARADA Akima, ITO Emiko, OHASHI Fumiya, WATANABE Tadashi, HATAZAWA Jun, MATSUURA Katsuhisa, SAWA Yoshiki:  Transplantation of human induced pluripotent stem cell-derived cardiomyocytes is superior to somatic stem cell therapy for restoring cardiac function and oxygen consumption in a porcine model of myocardial infarction.  Transplantation  103 (2) :291-298 , 2019.2
10. FUKUTOMI Yoshihiro, YOSHIMITSU Kitaro, TAMURA Manabu, MASAMUNE Ken, MURAGAKI Yoshihiro:  Quantitative Evaluation of Efficacy of Intraoperative Examination Monitor for Awake
Surgery.  World neurosurgery.  [Epub ahead of print] (**) :e1-e7 , 2019.2
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Review article
1. 村上大輔, 大木岳志, 高木 亮, 原田英明, 天野祐二, 大和雅之:  (特集 再生医療を学ぶ-Translational researchの再先端-)口腔粘膜上皮細胞シート移植による食道粘膜再生.  消化器病学サイエンス  3 (1) :32-37 , 2019.3
2. 村垣善浩, 新田雅之:  (7)グレード2神経膠腫に対する治療方針-手術・放射線治療・化学療法-.  脳神経外科  47 (2) :147-158 , 2019.2
3. 村垣善浩, 伊関洋, 正宗賢, 田村学, 岡本淳, 小林英津子, 生田聡子, 堀瀬友貴, 楠田佳緒:  脳神経外科と医工融合による医療機器開発.  脳神経外科  47 (2) :169-178 , 2019.2
4. NIKI Chiharu, KUMADA Takatsune , MARUYAMA Takashi, MURAGAKI Yoshihiro:  Role of Frontal Functions in Executing Routine Sequential Tasks.  Frontiers in Psychology  10 (169) :1-5 , 2019.2 Link
5. TAKAHASHI Hironobu*, OKANO Teruo:  Thermally-triggered fabrication of cell sheets for tissue engineering and regenerative medicine.  Advanced drug delivery reviews  138 (1) :276-292 , 2019.1
6. 正宗賢:  特集 機械工学が拓くIoT技術 メディカルIoT 治療室内IoTを中心に.  日本機械学会誌  120 (1201) :6-9 , 2018.12
7. SEKIYA Sachiko, MORIKAWA Shunichi, EZAKI Taichi, SHIMIZU Tatsuya:  Pathological Process of Prompt Connection between Host and Donor Tissue Vasculature Causing Rapid Perfusion of the Engineered Donor Tissue after Transplantation.  International Jornal of Molecular Sciences  19 (12) :4102 , 2018.12
8. 岡本淳, 正宗賢, 伊関洋, 村垣善浩:  治療の標準化・高度均てん化を実現するスマート治療室の開発.  光技術コンタクト  56 (11) :3-11 , 2018.11
9. 増田信奈子, 松浦勝久*:  心臓線維芽細胞の新たな役割としての血管新生抑制作用と臨床応用の可能性.  循環器内科  84 (5) :547-552 , 2018.11
10. 村垣善浩, 岡本淳, 正宗賢:  進化する手術室「スマート治療室SCOT」.  日本医師会雑誌  147 (8) :1614-1618 , 2018.11
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Case report
1. ISHIGURO Taichi, NITTA Masayuki, KOMORI Takashi, MARUYAMA Takashi, MURAGAKI Yoshihiro, KAWAMATA Takakazu:  Transient Focal MRI Abnormalities after Status Epilepticus Showed 11C-Methionine Uptake with PET in a Patient with Cerebral Cavernous Malformation.  World neurosurgery  114 :43-46 , 2018.6
Other
1. 村垣善浩:  大会後記 第28回日本光線力学学会 学術講演会.  JPA 日本光線力学学会 NEWS LETTER  20 :2-2 , 2019.3
2. 村垣善浩, 新田雅之:  初発膠芽腫に対する光線力学的療法.  光アライアンス  30 (3 通巻342) :34-37 , 2019.3
3. 堀瀬友貴:  医工学研究を始めたきっかけ.  日本機械学会誌  122 (1204) :50-50 , 2019.3
4. 荒井保明, 鈴木由香, 村垣善浩, 森光敬子:  医療機器の開発と臨床研究法.  医薬品医療機器レギュラトリーサイエンス  49 (12) :788-804 , 2018.12
5. MATSUOKA Go, EGUCHI SEIICHIRO, ANAMI Hidenori, ISHIKAWA Tatsuya, YAMAGUCHI Koji, NITTA Masayuki, MURAGAKI Yoshihiro, KAWAMATA Takakazu:  Ultrarapid evaluation of meningioma malignancy by intraoperative flow cytometry.  World neurosurgery  120 :320-327 , 2018.12
6. MURAGAKI Yoshihiro(SCOT):  Ultrasound and nanobots-a deadly duo against cancer.  Nature  563 (7731) :--- , 2018.11
7. 村垣善浩:  「スマート治療室」のスタンダードモデルが臨床研究開始.  映像情報Medical  50 (9) :86-86 , 2018.8
8. 大和雅之:  巻頭言「未承認再生医療提供問題」の解決と国民の啓発は学会の義務である.  再生医療  17 (3) :1-1 , 2018.8
9. 楠田佳緒:  学会印象記 「第41回未来医学研究会大会」.  再生医療  17 (3) :82-83 , 2018.8
10. 小林英津子:  コンピュータ外科と男女共同参画.  日本コンピュータ外科学会誌  20 (3) :119-119 , 2018.8
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■ Books
1. 高木亮, 大和雅之:  特定細胞加工物 / 再生医療等製品の安全性.  テキストブック 再生医療 ~創る、行う、支える~  188-200.  一般社団法人 日本再生医療学会,  東京, 2019.3 Link
2. 丸山隆志, 村垣善浩:  I  テント上病変 Transcortical approach.  新 脳神経外科手術のための解剖学  24-45.  メジカルビュー社,  東京都, 2019.1 Link
3. 齋藤太一, 村垣善浩:  グリオーマの再手術.  新NS NOW 16
Neurosurgical Re-Operations
脳神経外科における再手術・再治療  68-79.  メジカルビュー社,  東京都, 2018.12 Link
4. 大和雅之:  第11項 再生医療等製品の製剤化技術(細胞シート技術を中心に).  バイオロジクスの開発と品質・安全性確保  337-343.  株式会社エル・アイ・シー,  東京, 2018.12
5. 仁木千晴:  系列行為障害症候群の考えかた.  行為と動作の障害  21-34.  新興医学出版社,  東京, 2018.12
6. 大和雅之:  細胞シート工学.  ヴィジュアルでわかるバイオマテリアル  122-124.  秀潤社,  東京, 2018.11 Link
7. 関根秀一:  3次元組織構築のためのバイオリアクタの開発.  細胞培養加工施設の構築と運営管理の省力・省コスト化  179-185.  (株)技術情報協会,  東京, 2018.10 Link
8. 菊地鉄太郎:  細胞加工の工程自動化システム『組織ファクトリー』.  細胞培養加工施設の構築と運営管理の省力・省コスト化  259-268.  技術情報協会,  東京都, 日本, 2018.10
9. 村垣善浩, 丸山隆志:  IV 深部白質線維を考慮した外科手術 1.手術 2)側頭葉白質.  カダバーと動画で学ぶ脳深部アプローチ  175-186.  中外医学社,  東京都, 2018.10 Link
10. 大和雅之:  ティッシュ・エンジニアリング研究最前線.  先進医療NAVIGATOR 再生医療・細胞医療の研究と産業化の最前線  10-13.  日本医学出版,  東京, 2018.7
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■ Academic conference presentation
1. 松浦勝久, 佐々木大輔, 清水達也: Functional assessment of human bioengineered cardiac tissues in hypoxia and re-oxygenized environment for understanding myocardial functional recovery in heart failure.  第83回日本循環器学会学術集会,  横浜,  2019/03
2. ◎TAMURA Manabu: State-of-Art Neurosurgical Oncorogy -SCOT-.  WFNS Neuro-oncology Symposium-Developing Neuro-oncology,  Mumbai, India,  2019/03
3. ◎TAMURA Manabu: Intraoperative examination monitor for awake surgery (IEMAS) system lecture and demonstration.  Masterclass in Neurosurgical Oncology,  Mumbai, India,  2019/03
4. OKANO Teruo: Cell Sheet Tissue Engineering Regenerative Therapy for Clinical Applications and Their Advancement.  KUMP International Symposium,  Osaka, Japan,  2019/01 Link
5. ◎Ohtomo Haruki, Ohya Takashi, Kikuchi Tetsutaro, Sasaki Daisuke, Shimizu Tatsuya, Matsuura Katsuhisa, Fukuda Kenjiro, Someya Takao, Umezu Shinjiro: Fundamental study for measuring contractile force of cardiomyocytes by using ultraflexible film.  24th International Symposium on Artificial Life and Robotics (AROB 24th 2019),  Beppu, Japan,  2019/01
6. ◎MA Qingchuan, KOBAYASHI Etsuko, WANG Junchen, HARA Kazuaki, SUENAGA Hideyuki, MASAMUNE Ken, SAKUMA Ichiro: Drilling Accuracy Evaluation on An Autonomous OMS System.  The 14th Asian Conference on Computer Aided Surgery (ACCAS 2018),  Shanghai,China,  2018/11 Link
7. Matsuura Katsuhisa, Sasaki Daisuke, SHIMIZU Tatsuya: Functional Assessment of Human Bioengineered Cardiac Tissues in Hypoxia and Re-oxygenized Environment for understanding myocardial function Recovery in Heart Failure.  AHA Scientific Sessions 2018,  Chicago, USA,  2018/11
8. Matsuuta Katsuhisa: Development of scalable 3D suspension bioreactor system for human iPS cell expansion and differentiation.  The 31st Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2018 Tsukuba),  Tsukuba, Japan,  2018/11
9. ◎SHIMIZU Tatsuya: Fabrication of Vascularized Tree-Dimensional(3-D) Tissues.  4th Stem Cells and Cellular Terapy Conference,  Riyadh, Saudi Arabia,  2018/10
10. ◎Matsuura Katsuhisa: Development of human cardiac tissue from iPS cells for transplantation.  4th Stem Cells and Cellular Therapy Conference,  Riyadh, Saudi Arabia,  2018/10
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