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Department of Physiology, Division of Molecular and Cellular Physiology
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■ Summary
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■ Research grants & projects
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1.
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Budget amount：\55,291,500 (Principal investigator)
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2.
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(Grant No.：16H05123)
Budget amount：\2,700,000 (Principal investigator)
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3.
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Budget amount：\1,900,000 (Principal investigator)
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4.
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(Grant No.：17K18135)
Budget amount：\600,000 (Principal investigator)
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5.
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(Grant No.：16K18517)
Budget amount：\500,000 (Principal investigator)
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6.
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Takeda Science Foundation
Budget amount：\2,000,000 (Principal investigator)
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■ Research works
| Journal |
Book |
Presentation |
Other presentations |
| Japanese | English |
Japanese | English |
Domestic | international |
| First author | Corresponding
Author | Co-author | First author | Corresponding
Author | Co-author |
First author | Co-author | First author | Co-author |
Presenter | Co-presenter | Presenter | Co-presenter |
Presenter | Co-presenter |
| 0 | 0 | 0 | 0 | 1 | 5 |
0 | 1 | 0 | 0 |
3 | 3 |
2 | 4 |
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■ Published papers
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Original article
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1.
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Uehara Tomoko, Suzuki Hidenori, Okamoto Nobuhiko, Kondoh Tatsuro, Ahmad Ayesha, O'Connor Bridget C, Yoshina Sawako, Mitani Shohei, Kosaki Kenjiro, Takenouchi Toshiki：
Pathogenetic basis of Takenouchi-Kosaki syndrome: Electron microscopy study using platelets in patients and functional studies in a Caenorhabditis elegans model.
Scientific reports
9
(1)
：4418
, 2019.3
DOI:10.1038/s41598-019-40988-7
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2.
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Kanaki Nanako, Matsuda Ayako, Dejima Katsufumi, Murata Daisuke, Nomura Kazuko H, Ohkura Takashi, Gengyo-Ando Keiko, Yoshina Sawako, Mitani Shohei, Nomura Kazuya：
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase is indispensable for oogenesis, oocyte-to-embryo transition, and larval development of the nematode Caenorhabditis elegans.
Glycobiology
29
(2)
：163-178
, 2019.2
DOI:10.1093/glycob/cwy104
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3.
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Chen Yu-Zen, Klöditz Katharina, Lee Eui-Seung, Nguyen Diemmy Pham, Yuan Quan, Johnson Jack, Lee-Yow Yannick, Hall Adam, Mitani Shohei, Xia Ning-Shao, Fadeel Bengt, Xue Ding：
Structure and function analysis of the C. elegans aminophospholipid translocase TAT-1.
Journal of cell science
132
(5)
：1-7
, 2019.2
DOI:10.1242/jcs.227660
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4.
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Kage-Nakadai Eriko, Sun Simo, Iwata Satoru, Yoshina Sawako, Nishikawa Yoshikazu, Mitani Shohei：
The small GTPase ARF-1.2 is a regulator of unicellular tube formation in Caenorhabditis elegans.
The journal of physiological sciences : JPS
69
(1)
：47-56
, 2019.1
DOI:10.1007/s12576-018-0617-5
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5.
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Miyasaka Tomohiro, Shinzaki Yuki, Yoshimura Satomi, Yoshina Sawako, Kage-Nakadai Eriko, Mitani Shohei, Ihara Yasuo：
Imbalanced Expression of Tau and Tubulin Induces Neuronal Dysfunction in C. elegans Models of Tauopathy.
Frontiers in neuroscience
12
：415
, 2018.6
DOI:10.3389/fnins.2018.00415
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6.
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Hori Sayaka, Oda Shigekazu, Suehiro Yuji, Iino Yuichi, Mitani Shohei：
OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses.
PLoS genetics
14
(6)
：e1007477
, 2018.6
DOI:10.1371/journal.pgen.1007477
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■ Books
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1.
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吉名佐和子, 三谷昌平：
線虫をモデル生物としたヒト疾患の解析.
生物の科学 遺伝
492-497.
エヌ・ティー・エス,
東京,
2018.9
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■ Academic conference presentation
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1.
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Keita Yoshida, Sawako Yoshina, Yuji Suehiro, Shohei Mitani：
Analysis of the mechanism regulating intercellular transport of silencing RNA in C. elegans.
9th Federation of the Asian and Oceanian Physiological Societies Congress,
Kobe, Japan,
2019/03
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2.
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Luna Izuhara,Sawako Yoshina,Sayaka Higuchi,Yuji Suehiro,Shohei Mitani：
Molecular network search for bcl-7 related factors.
9th Federation of the Asian and Oceanian Physiological Societies Congress,
Kobe, Japan,
2019/03
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3.
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SUEHIRO Yuji, MITANI Shohei：
Sensory integration and behavioral choice regulated by the meta- botropic glutamate receptor.
9th Federation of the Asian and Oceanian Physiological Societies Congress,
Kobe, JAPAN,
2019/03
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4.
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Dejima Katsufumi, Imae Rieko, Suehiro Yuji, Mitani Shohei：
An endosome-resident zinc transporter negatively regulates systemic dsRNA spreading in C. elegans.
Federation of the Asian and Oceanian Physiological Society (FAOPS 2019),
Kobe, Japan,
2019/03
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5.
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YOSHINA Sawako, MITANI Shohei：
Analysis of Molecular and Cellular Roles of the GON domain in ER-to-Golgi transport.
アジア・オセアニア生理学連合第9回大会,
神戸、日本,
2019/03
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6.
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◎Dejima Katsufumi, Imae Rieko, Suehiro Yuji, Mitani Shohei：
An endomembrane-resident zinc transporter negatively regulates systemic RNAi in C. elegans.
C. elegans development cell biology, and gene expression,
Barcelona, Spain,
2018/06
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7.
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◎堀沙耶香, 三谷昌平：
Forkhead box transcription factors determine synaptic specificity of a strength-dependent sensory processing circuit.
次世代脳冬のシンポジウム,
東京、日本,
2018/12
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8.
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◎本橋智子、吉名佐和子、堀沙耶香、末廣勇司、出嶋克史、吉田慶太、伊豆原るな、三谷昌平：
NBRP「線虫」：遺伝子機能解析のための欠失変異体の収集・保存・提供.
第41回日本分子生物学会年会,
横浜,
2018/11
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9.
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伊豆原 るな、吉名 佐和子、樋口 清香、末廣 勇司、三谷 昌平：
bcl-7関連因子の探索.
線虫研究の未来を創る会,
三島,日本,
2018/09
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10.
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◎Sayaka Hori, Shohei Mitani：
Forkhead box D4 transcription factor homolog, unc-130, affects sensory processing depending on stimulus strength.
Neuroscience2018,
Kobe, Japan,
2018/07
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11.
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◎本橋智子、吉名佐和子、堀沙耶香、末廣勇司、出嶋克史、吉田慶太、伊豆原るな、三谷昌平：
NBRP「線虫」：遺伝子機能解析のための欠失変異体の収集・保存・提供.
第41回日本神経科学会大会,
神戸,
2018/07
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12.
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SUEHIRO Yuji, MITANI Shohei：
The analysis of mGluR function for the behavioral choice induced by multiple sensory inputs using C.elegans.
The 41st Annual Meeting of the Japan Neuroscience Society,
Kobe, JAPAN,
2018/07
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