Faculty Information

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Department of Physiology, Division of Molecular and Cellular Physiology

Summary	Research grants & projects	Published papers
Books	Academic conference presentation

Professor：

MITANI Shohei

Assistant Professor：
榊　建二郎
中臺　枝里子

Assistant Professor：
   HORI Sayaka
   Yoshina Sawako
   Rieko Imae
   Suehiro Yuji
   Motohashi Tomoko

■ Summary

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■ Research grants & projects

1.	Budget amount：\93,571,000 (Principal investigator)
2.	(Grant No.：24390053) Budget amount：\2,800,000 (Principal investigator)
3.	(Grant No.：23790256) Budget amount：\1,300,000 (Principal investigator)
4.	(Grant No.：24790092) Budget amount：\1,300,000 (Principal investigator)
5.	(Grant No.：25870761) Budget amount：\1,300,000 (Principal investigator)
6.	(Grant No.：25870759) Budget amount：\1,300,000 (Principal investigator)
7.	(Grant No.：25830018) Budget amount：\910,000 (Principal investigator)
8.	Budget amount：\2,200,000 (Principal investigator)
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■ Research works

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Japanese

English

Japanese

English

Domestic

international

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■ Published papers

Original article
1.	Xie C, Miyasaka T, Yoshimura S, Hatsuta H, Yoshina S, Kage-Nakadai E, Mitani S, Murayama S, Ihara Y： The homologous carboxyl-terminal domains of microtubule-associated protein 2 and Tau induce neuronal dysfunction and have differential fates in the evolution of neurofibrillary tangles. PLoS ONE 9 (2) ：e89796 , 2014.2 DOI:10.1371/journal.pone.0089796
2.	Dejima Katsufumi, Takemura Masahiko, Nakato Eriko, Peterson Jesse, Hayashi Yoshiki, Kinoshita-Toyoda Akiko, Toyoda Hidenao, Nakato Hiroshi： Analysis of Drosophila glucuronyl C5-epimerase: implications for developmental roles of heparan sulfate sulfation compensation and 2-O-sulfated glucuronic acid. The Journal of biological chemistry 288 (48) ：34384-93 , 2013.11 DOI:10.1074/jbc.M113.499269
3.	Smith CJ, O'Brien T, Chatzigeorgiou M, Spencer WC, Feingold-Link E, Husson SJ, Husson SJ, Hori S, Mitani S, Gottschalk A, Schafer WR, Miller DM III： Sensory Neuron Fates Are Distinguished by a Transcriptional Switch that Regulates Dendrite Branch Stabilization. Neuron 79 ：266-280 , 2013.7
4.	Ding Y-H, Du Y-G, Luo S, Li Y-X, Li T-M, Yoshina S, Wang X, Klage K, Mitani S, Ye K, Dong M-Q： Characterization of PUD-1 and PUD-2, Two Proteins Up-Regulated in a Long-Lived daf-2 Mutant. PLoS ONE 8 (6) ：e67158 , 2013.6
5.	Iwata, S., Miyazawa, Y., Fujii, N., Takahashi, H： MIZ1-regulated hydrotropism functions in the growth and survival of Arabidopsis thaliana under natural conditions. Annals of Botany 112 (1) ：103-114 , 2013.5 DOI:0.1093/aob/mct098
6.	Sasaki A, Nakae I, Nagasawa M, Hashimoto K, Abe F, Saito K, Fukuyama M, Gengyo-Ando K, Mitani S, Katada T and Kontani K： Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans. Molecular biology of the cell 24 (10) ：1584-1592 , 2013.5
7.	Ohba Y, Sakuragi T, Kage-Nakadai E, Tomioka NH, Kono N, Imae R, Inoue A, Aoki J, Ishihara N, Inoue T, Mitani S and Ara H： Mitochondria-type GPAT is requied for mitochodrial fusion. The EMBO journal 32 (9) ：1265-1279 , 2013.5
8.	Li X, Chen B, Yoshina S, Cai T, Yang F, Mitani S, and Wang X： Inactivation of Caenorhabditis elegans aminopeptidase DNPP-1 restores endocytic sorting and recycling in tat-1 mutants. Molecular biology of the cell 24 ：1163-1175 , 2013.4
9.	Sakaki Kenjiro, Kaufman Randal J： Interaction between quality control systems for ER protein folding and RNA biogenesis. Worm 2 (2) ：e23006 , 2013.4 DOI:10.4161/worm.23005
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Other
1.	Mikihiko Kawai^†, Taiki Futagami, Atsushi Toyoda, Yoshihiro Takaki, Shinro Nishi, Sayaka Hori, Wataru Arai, Taishi Tsubouchi, Yuki Morono, Ikuo Uchiyama, Takehiko Itoh, Asao Fujiyama, Fumio Inagaki, Hideto Takami*： High frequency of phylogenetically diverse reductive dehalogenase-homologous genes in deep subseafloor sedimentary metagenomes. Frontiers in Extreme Microbiology 5 (80) ：1-15 , 2014.3
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■ Books

1.	Yoshina Sawako, Mitani Shohei： ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif, 9). Atlas of Genetics and Cytogenetics in Oncology and Haematology 497-499. INIST, France, 2013.12
2.	NAKADAI Eriko, MITANI Shohei： Developmental Genetics of Caenorhabditis elegans. Brenner's Encyclopedia of Genetics 2nd edition 308-310. Academic Press, London, UK, 2013.4
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■ Academic conference presentation

1.	Suehiro Yuji, Mitani Shohei： Odorant choice behavior and systematic reverse genetics approach to reveal molecular mechanisms underlying the behavior. 19th International C. elegans Meeting, Los Angeles, 2013/06
2.	◎Hori S, Oda S, Suehiro Y, Iino Y, Mitani S： Combination of optogenetics and reverse genetics: novel behavior screening for regulators of neural differentiation. 19th International C. elegans Meeting, Los Angeles, USA, 2013/06
3.	Eriko Kage-Nakadai, ◎Rieko Imae, Osamu Funatsu, Sayaka Hori, Yuji Suehiro, Sawako Yoshina, Shohei Mitani： A conditional knockout system based on the single/low-copy integration of transgenes in C. elegans. 19th International C. elegans Meeting, Los Angeles, USA, 2013/06
4.	◎本橋智子, 吉名佐和子, 中臺枝里子, 堀沙耶香, 今江理恵子, 末廣勇司, 三谷昌平： NBRP「線虫」：遺伝子機能解析のための欠失変異体の収集・保存・提供. 第36回日本分子生物学会, 神戸, 2013/12
5.	◎榊建二郎, 吉名佐和子, Kaufman Randal J, 三谷昌平： RNA品質管理と小胞体品質管理を結ぶインターフェイスの解析. 第65回日本細胞生物学会年会, 名古屋, 2013/06
6.	◎本橋智子, 吉名佐和子, 中臺枝里子, 堀沙耶香, 今江理恵子, 末廣勇司, 舩津修, 三谷昌平： NBRP「線虫」：遺伝子機能解析のための欠失変異体の収集・保存・提供. 第60回日本実験動物学会年会, 筑波, 2013/05
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^＊：Corresponding Author
^†：First Author
◎：Presenter