SHIYOUDA Morio    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Professor (Fixed Term)
Language	English
Title	Clinical Phases Vary with Disease Stage in Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia
Conference	The 79th Annual Scientific Meeting of the Japanese Circulation Society
Promoters	Japanese Circulation Society
Conference Type	Nationwide Conferences
Presentation Type	Speech
Lecture Type	General
Publisher and common publisher	◎KIKUCHI Noriko, YUMINO Dai, TOBITA Naoshige, HATTORI Hidetoshi, SERIZAWA Naoki, SUZUKI Atsushi, SUZUKI Tsuyoshi, SHIGA Tsuyoshi, SHODA Morio, HAGIWARA Nobuhisa
Date	2015/04/24
Venue (city and name of the country)	Osaka, JAPAN
Society abstract	PROGRAM JCS 2015 180
Summary	Background: Clinical observation suggests that arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) could have four different clinical phases: the concealed phase, electrical phase, failure phase and end-stage phase. However, these clinical phases are fully elucidated during long term follow-up period.Methods and Results: Between 1974 and 2012 at a tertiary center in Japan, we enrolled 90 patients in whom ARVC/D was diagnosed based on the modified Task Force Criteria 2010. During follow up period of 10.2±7.1 years, 47 patients experienced ventricular arrhythmia, 28 were hospitalized for heart failure and 21 patients died(Figure). Of the 28 HF hospitalization patients, 24 (86%) had experienced ventricular arrhythmia prior to HF hospitalization. Conclusion: Clinical phases vary with stage of disease, such as life-threatening ventricular arrhythmia, heart failure hospitalization, and death.