所属 医学部 医学科（東京女子医科大学病院） 職種 教授
|発表タイトル||Ventricular Arrhythmias after Left Ventricular Assist Device Implantation|
|発表者・共同発表者||◎服部英敏, 鈴木敦, 志賀剛, 芹澤直紀, 南雄一郎, 庄田守男, 勝部健, 立石実, 梅原伸大, 齋藤聡, 布田伸一, 山崎健二, 萩原誠久|
|学会抄録||第81回日本循環器学会学術集会 プログラム集 213|
|概要||Background: Left ventricular assist device (LVAD) has become an important treatment option for the patients with advanced heart failure. Ventricular arrhythmia (VA) is common in patients supported with LVAD. With the growing use of LVAD, the recognition and management of VA have become big issue. The aim of this study was to asses the incidence and clinical consequence of VA in patients with LVAD, especially during long‒term support.
Methods and Results: We retrospectively studied 61 patients who were implanted LVAD between 1997 and 2014 at our institution. The mean duration of LVAD support was 518 days (interquartile range, 132 to 1011) and VA occurred in 28 patients (46%). While 13patients (46%) experienced their first episode of VA during early‒post operative period (<30days), 8 patients (29%) experienced their first episode of VA 1‒year after LVAD implantation. Pre‒operative VA was the predictor of post‒operative VA (HR3.32, 95% CI 1.47‒7.70, p<0.01). Patients who experienced post‒operative VA had significantly higher mortality rate compared with those without (64% versus 29%; P<0.01).
Conclusions: In LVAD patients, VA was common and still occurred 1‒year after LVAD implantation. VA was associated with an increased risk of mortality. In such patients, preventing and treating VA are needed.