ナカニシ トシオ   NAKANISHI Toshio
  中西 敏雄
   所属   医学部 医学科(東京女子医科大学病院)
   職種   特任教授
言語種別 英語
発表タイトル Long-Term Outcomes of the Fontan Operation: Forty Years of Experience at a Single Institute
会議名 The 81st Annual Scientific Meeting of the Japanese Circulation Society (JCS2017)
主催者 Japanese Circulation Society
学会区分 全国規模の学会
発表形式 口頭
講演区分 一般
発表者・共同発表者◎MORI Hiroki, SHIMADA Eriko, SHINOHARA Tokuko, INAI Kei, NAKANISHI Toshio
発表年月日 2017/03/18
開催地
(都市, 国名)
Kanazawa, JAPAN
学会抄録 PROGRAM JCS 2017 309
概要 Introduction: Although the survival rate of individuals with single-ventricular hearts has been dramatically improved by the Fontan operation, the long-term prognosis is as yet unclear.
Purpose: To clarify the long-term outcomes of the Fontan operation and to describe the clinical condition of long-term survivors.
Design and Setting: Retrospective observational study set at a single institute.
Methods: We analyzed 628 patients who had undergone the Fontan procedure in our institute between 1974 and 2013.
Results: Overall, survival rate declines about 10% every 10 years. Forty-five patients underwent the Fontan operation more than 30 years ago; of these, 20 are alive and 25 have died. All long-term survivors had heart failure (NYHA I:0, II:17, III:3, IV:0). Nineteen (95%) of the 20 long-term survivors had a history of atrial tachycardia and 11 (40%) have had at least one thromboembolic event.
Conclusion: Prognosis of the Fontan operation has improved in recent years. Further refinement of this treatment strategy is needed to improve event-free survival.