シガ　ツヨシ   Tsuyoshi Shiga   志賀　剛    所属   医学部 医学科（東京女子医科大学病院）    職種   客員教授
言語種別	英語
発表タイトル	Muscle Wasting during Heart Failure Hospitalization: Insights from Bioelectrical Impedance Analysis
会議名	The 79th Annual Scientific Meeting of the Japanese Circulation Society
主催者	Japanese Circulation Society
学会区分	全国規模の学会
発表形式	ポスター掲示
講演区分	一般
発表者・共同発表者	◎HAMADA Kazuyuki, HARUKI Shintaro, MINAMI Yuichiro, KITAMURA Kazutaka, SERIZAWA Naoki, OKAYAMA Dai, ARASHI Hiroyuki, JUJO Kentaro, SHIGA Tsuyoshi, HAGIWARA Nobuhisa
発表年月日	2015/04/24
開催地 （都市, 国名）	Osaka, JAPAN
学会抄録	PROGRAM JCS 2015 212
概要	Background: Although muscle wasting (sarcopenia) has been recognized as an important and frequent co-morbidity in ambulatory outpatients with chronic heart failure, the prevalence and predictor of muscle wasting in hospitalized heart failure (HHF) patients is unclear. In this study, we examine the change of muscle mass during heart failure hospitalization by bioelectrical impedance analysis (BIA). Methods: We studied 45 HHF patients who examined muscle mass by BIA between February and August 2013. BIA of each patient was measured by InBodyS20 on admission and discharge. Results: During hospitalization, decrease in muscle mass was observed in 41 (91%) of 45 HHF patients, and the median percent change of muscle mass during hospitalization (ΔM%) was -8%. There was a higher proportion of female and emergency admission to cardiac care unit (CCU) in patients with muscle wasting (group W: ΔM%≤-8%, N=22) than those without, and 87% of female patients admitted to CCU were in the group W. In addition, patients with group W had significantly higher B-type natriuretic peptide, lower albumin and hemoglobin level, and larger inferior vena cava (IVC) diameter on admission. Furthermore, we found a significant negative correlation between ΔM% and IVC diameter (r=-0.558; p<0.001). Conclusions: Hospitalization may put a heart failure patients at risk of muscle wasting, especially in female patients requiring urgent intensive therapy and/or patients with severe venous congestion.