ASHIHARA Kyomi
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Assistant Professor |
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Language | English |
Title | Predictor of Aortic Root Dilatation in Adolescent and Adult Patients with Surgically Repaired Ventricular Septal Defect |
Conference | The 79th Annual Scientific Meeting of the Japanese Circulation Society |
Promoters | Japanese Circulation Society |
Conference Type | Nationwide Conferences |
Presentation Type | Speech |
Lecture Type | General |
Publisher and common publisher | ◎SAITO Chihiro, FUKUSHIMA Keiko, FUKUSHIMA Noritoshi, MATSUMURA Goki, HATAKEYAMA Shinya, HAYASHI Keiko, ARAI Kotaro, ASHIHARA Kyomi, HAGIWARA Nobuhisa |
Date | 2015/04/26 |
Venue (city and name of the country) |
Osaka, JAPAN |
Society abstract | PROGRAM JCS 2015 630 |
Summary | Background: Aortic root dilatation (ARD) in congenital heart disease is a deleterious issue induced to aortic regurgitation (AR), aortic aneurysm, and rupture. We sought to determine the predictors of ARD in patients with repaired ventricular septal defect (VSD). Methods and Results: This cross-sectional study included 157 patients with surgically repaired VSD. Echocardiographic findings were assessed to measure the aortic root in a parasternal long-axis view at the level of the sinus of Valsalva. Absolute diameter ≥38mm of aortic root was defined as ARD. The prevalence of the ARD was 16.6% (n=26). After adjustment for gender, duration of shunt, follow-up period after operation, and the presence of AR in a multivariate logistic model, VSD patients with non-subarterial-type was found to have ARD (odds ratio 7.55, 95% confidence interval 1.65 to 34.50, p = 0.009), compared to those with subarterial-type, commonly observed in Asian. Patients with pre-operative right-, or non-coronary cusp prolapsing (RNCCP) was found to have ARD (odds ratio 20.14, 95% confidence interval 3.10 to 130.63, p =0.002), compared in patients without pre-operative RNCCP. Furthermore, larger defect diameter was found to be a risk factor for ARD (odds ratio 1.18, 95% confidence interval 1.06 to 1.31, p =0.002). Conclusion: Anatomical and morphological features (Non-subarteial-types, the presence of pre-operative RNCCP, and defect size) in VSD were independent predictors for the ARD. |