所属 医学部 医学科（東京女子医科大学病院） 職種 特任教授
|発表タイトル||Efficacy of expandable hydrogel polymer coil embolization for aortopulmonary collateral artery. Efficacy for reduction of number of coils and prevention for recanalization.|
|会議名||CSI Asia-Pacific 2017|
|発表者・共同発表者||◎KOGURE Tomohito, SUGIYAMA Hisashi, ISHII Tetsuko, YAMAGUCHI Junichi, BOKU Hitomi, HAGIWARA Nobuhisa|
Aortopulmonary collateral arteries (APCA) in single ventricular physiology is related to plural effusion or ICU stay period after TCPC. Although coil embolization is effective for those, it requires a large number of coils. In addition, bare platinum coil often causes recanalization. Expandable hydrogel polymer coil (AZUR®) has unique characteristics represented by greater filling with fewer coils and is expected to prevent recanalization.
Reduction of the number of coils and prevention from recanalization by AZUR coil are retrospectively evaluated.
Study I: Total 11 vessels in 7 patients underwent coil embolization with AZUR for de novo APCAs from internal mammary artery (IMA) (AZUR group). They were compared with age matched patients who were treated with bare platinum coil (control group).
Study II: In 2 patients, AZUR was deployed in recanalized APCAs which have been previously treated with bear platinum coils. One patient had racemose hemangioma of the bronchial artery with fatal recurrent hemoptysis.
Study I: The mean age of the patients were 5.6 years (2-17) and the mean diameter of IMA was 2.5 mm (2.0-2.8 mm). The number of coils was fewer in AZUR group as compared with control group (4.3±1.8 vs 6.5±2.8, P=0.04).
Study II: Complete occlusion by AZUR was demonstrated in both patients. Recurrent hemoptysis was stopped 2 years after coil embolization in the child with racemose hemangioma.
AZUR could contribute to reduce number of coils in APCAs and also be effective against recanalization even in Racemose hemangioma.