アライ コウタロウ   ARAI Kotaro
  新井 光太郎
   所属   医学部 医学科(東京女子医科大学病院)
   職種   助教
言語種別 英語
発表タイトル Right Ventricular Function has Prognostic Values in Acute Heart Failure Patients with Reduced but NOT Preserved Left Ventricular Systolic Function
会議名 The 83rd Annual Scientific Meeting of the Japanese Circulation Society (JCS2019)
主催者 Japanese Circulation Society
学会区分 全国規模の学会
発表形式 口頭
講演区分 一般
発表者・共同発表者◎SAITO Chihiro, JUJO Kentaro, KAMETANI Motoko, ARAI Kotaro, MINAMI Yuichiro, ABE Takuro, ASHIHARA Kyomi, HAGIWARA Nobuhisa
発表年月日 2019/03/31
開催地
(都市, 国名)
Yokohama, JAPAN
概要 *Oral Presentation (English)27 Heart Failure (Diagnosis/Prognosis)
Background: Right ventricular (RV) dysfunction adversely affects prognosis in congestive heart failure patients with reduced left ventricular ejection fraction (LVEF). However,little evidence exists regarding the prognostic implication of RV function indices in hospitalized acute heart failure (AHF) patients. Methods: This observational study included 802 urgently hospitalized and discharged alive AHF patients with information of RV tissue Doppler imaging systolic velocity (RV-TDI s´). Of them, 591 patients with reduced (<50%; HFrEF) and 211 with preserved (≥50%; HFpEF) LVEF were analyzed. The primary endpoint was all-cause mortality. Results: ROC curve for all-cause mortality indicated RV-TDI s´ cut-off points as 7.5 and 12.4 in HFrEF and HFpEF, respectively. In HFrEF, Kaplan-Meier analysis showed a significantly higher mortality in patients with RVTDI s´ <7.5; however, in HFpEF, there was no significant difference (Figure). RV-TDI s´ <7.5 was an independent predictor of mortality in HFrEF (HR: 2.38 (95% CI: 1.06- 5.37)), even after adjustment for confounders. Conclusions: The simple index RV-TDI s´ may predict all-cause mortality in AHF patients with reduced LVEF, but not with preserved LVEF.