JUJO Kentaro    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Assistant Professor
Language	English
Title	Right Ventricular Function has Prognostic Values in Acute Heart Failure Patients with Reduced but NOT Preserved Left Ventricular Systolic Function
Conference	The 83rd Annual Scientific Meeting of the Japanese Circulation Society (JCS2019)
Promoters	Japanese Circulation Society
Conference Type	Nationwide Conferences
Presentation Type	Speech
Lecture Type	General
Publisher and common publisher	◎SAITO Chihiro, JUJO Kentaro, KAMETANI Motoko, ARAI Kotaro, MINAMI Yuichiro, ABE Takuro, ASHIHARA Kyomi, HAGIWARA Nobuhisa
Date	2019/03/31
Venue (city and name of the country)	Yokohama, JAPAN
Summary	*Oral Presentation (English)27 Heart Failure (Diagnosis/Prognosis) Background: Right ventricular (RV) dysfunction adversely affects prognosis in congestive heart failure patients with reduced left ventricular ejection fraction (LVEF). However,little evidence exists regarding the prognostic implication of RV function indices in hospitalized acute heart failure (AHF) patients. Methods: This observational study included 802 urgently hospitalized and discharged alive AHF patients with information of RV tissue Doppler imaging systolic velocity (RV-TDI s´). Of them, 591 patients with reduced (<50%; HFrEF) and 211 with preserved (≥50%; HFpEF) LVEF were analyzed. The primary endpoint was all-cause mortality. Results: ROC curve for all-cause mortality indicated RV-TDI s´ cut-off points as 7.5 and 12.4 in HFrEF and HFpEF, respectively. In HFrEF, Kaplan-Meier analysis showed a significantly higher mortality in patients with RVTDI s´ <7.5; however, in HFpEF, there was no significant difference (Figure). RV-TDI s´ <7.5 was an independent predictor of mortality in HFrEF (HR: 2.38 (95% CI: 1.06- 5.37)), even after adjustment for confounders. Conclusions: The simple index RV-TDI s´ may predict all-cause mortality in AHF patients with reduced LVEF, but not with preserved LVEF.