JUJO Kentaro    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Assistant Professor
Language	English
Title	Muscle Wasting during Heart Failure Hospitalization: Insights from Bioelectrical Impedance Analysis
Conference	The 79th Annual Scientific Meeting of the Japanese Circulation Society
Promoters	Japanese Circulation Society
Conference Type	Nationwide Conferences
Presentation Type	Poster notice
Lecture Type	General
Publisher and common publisher	◎HAMADA Kazuyuki, HARUKI Shintaro, MINAMI Yuichiro, KITAMURA Kazutaka, SERIZAWA Naoki, OKAYAMA Dai, ARASHI Hiroyuki, JUJO Kentaro, SHIGA Tsuyoshi, HAGIWARA Nobuhisa
Date	2015/04/24
Venue (city and name of the country)	Osaka, JAPAN
Society abstract	PROGRAM JCS 2015 212
Summary	Background: Although muscle wasting (sarcopenia) has been recognized as an important and frequent co-morbidity in ambulatory outpatients with chronic heart failure, the prevalence and predictor of muscle wasting in hospitalized heart failure (HHF) patients is unclear. In this study, we examine the change of muscle mass during heart failure hospitalization by bioelectrical impedance analysis (BIA). Methods: We studied 45 HHF patients who examined muscle mass by BIA between February and August 2013. BIA of each patient was measured by InBodyS20 on admission and discharge. Results: During hospitalization, decrease in muscle mass was observed in 41 (91%) of 45 HHF patients, and the median percent change of muscle mass during hospitalization (ΔM%) was -8%. There was a higher proportion of female and emergency admission to cardiac care unit (CCU) in patients with muscle wasting (group W: ΔM%≤-8%, N=22) than those without, and 87% of female patients admitted to CCU were in the group W. In addition, patients with group W had significantly higher B-type natriuretic peptide, lower albumin and hemoglobin level, and larger inferior vena cava (IVC) diameter on admission. Furthermore, we found a significant negative correlation between ΔM% and IVC diameter (r=-0.558; p<0.001). Conclusions: Hospitalization may put a heart failure patients at risk of muscle wasting, especially in female patients requiring urgent intensive therapy and/or patients with severe venous congestion.