ARASHI Hiroyuki
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Assistant Professor
Language English
Title Novel prognostic value of PARIS score in patients after rotational atherectomy to the severely calcified coronary artery
Conference Euro PCR 2018
Promoters European Society of Cardiology
Conference Type International society and overseas society
Presentation Type Poster notice
Lecture Type General
Publisher and common publisher◎TANAKA Kazuki, JUJO Kentaro, KONAMI Yutaka, OOTSUKI Hisao, NAKAO Masashi, ARASHI Hiroyuki, YAMAGUCHI Junichi, HAGIWARA Nobuhisa
Date 2018/05/23
Venue
(city and name of the country)
Paris, FRANCE
Summary AIMS
Rotational atherectomy (RA) is a promising strategic option for technical success of percutaneous coronary intervention (PCI) to severely calcified lesions. However, long-term clinical prognosis after RA has not been fully discussed in the drug-eluting stent (DES) era. PARIS score can separately predict embolic and bleeding events after PCI. We aimed to validate PARIS score in predicting clinical outcomes of patients who were treated with RA.

METHODS AND RESULTS
Total of 404 patients undergoing PCI with RA between 2004 and 2013 was enrolled. Median follow-up period was 1,521 days. The rate of coronary thrombotic events (CTEs: stent thrombosis and myocardial infarction) and major adverse cardiac events (MACE: CTEs, cardiovascular death, and target vascular revascularization) were compared among patients with PARIS-CTEs low (n=123), intermediate (n=109), and high (n=172) score group. Additionally, incidence of major bleeding (MB) was also compared among PARIS-MB low (n=35), intermediate (n=159), and high (n=210) score group.As a result, Kaplan-Meier analysis revealed that both rates of CTEs and MB were comparable among the groups (4-year CTEs: 4.2%, 9.2%, 7.5%, p=0.11, MB: 7.2%, 5.5%, 10.0%, p=0.22). In contrast, MACE rate was significantly higher in the higher PARIS-CTEs score group (4-year MACE: 22.8%, 44.4%, 52.5%, p<0.001).

CONCLUSIONS
PARIS score may predict long-term MACE, but not each of CTEs or bleeding events in patients after RA in the DES era.