ARASHI Hiroyuki
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Assistant Professor
Language English
Title Antithrombotic Therapy in Atrial Fibrillation Patients with Chronic Kidney Disease Undergoing Percutaneous Coronary Intervention-From Multicenter Cohort Study-
Conference The 79th Annual Scientific Meeting of the Japanese Circulation Society
Promoters Japanese Circulation Society
Conference Type Nationwide Conferences
Presentation Type Speech
Lecture Type General
Publisher and common publisher◎OOTSUKI Hisao, WATANABE Misahiro, KAMISHIMA Kazuho, OKAYAMA Dai, HARUKI Shintaro, JUJO Kentaro, ARASHI Hiroyuki, MINAMI Yuichiro, TAKAGI Atsushi, OOTA Yoshimi, TANAKA Hiroyuki, MORI Fumiaki, FUJII Shinya, HONDA Atsushi, YAMAGUCHI Junichi, HAGIWARA Nobuhisa
Date 2015/04/25
Venue
(city and name of the country)
Osaka, JAPAN
Society abstract PROGRAM JCS 2015 503
Summary Background: The relation between antithrombotic therapy and prognosis in atrial fibrillation (AF) patients with chronic kidney disease (CKD) undergoing percutaneous coronary intervention (PCI) is unclear. Methods and Results: Consecutive 450 patients with AF undergoing PCI were enrolled at 8 medical centers. Among them, we examined 198 patients with CKD (eGFR < 60ml/min/1.73m2, without maintenance hemodialysis), including 130 patients (66%) on triple therapy (TT; warfarin + dual antiplatelet therapy [DAPT]) and 68 patients (34%) on DAPT at the time of PCI. The incidence of major adverse cerebro-cardiovascular events (MACCE; cardiac death, non-fatal myocardial infarction and stroke) and bleeding complications were evaluated. Patient´s characteristics and Kaplan-Meier curve of clinical outcomes are shown below. Conclusion: AF patients with CKD on TT had similar incidence of MACCE but more bleeding complications compared to DAPT patients.