AMANO KUNIHIKO    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position
Language	English
Title	Safety of surgery for the gastric cancer patients taking warfarin potassium.
Conference	38th Biennial World Congress of the International College of Surgeons
Conference Type	International society and overseas society
Presentation Type	Speech
Lecture Type	General
Publisher and common publisher	◎Kunihiko Amano, Seshimo Akiyoshi, Matsuoka Azusa, Kasuga Makiko, Miyake Kunitomo, KAMEOKA Shingo
Date	2012/11/08
Venue (city and name of the country)	Brisbane, Australia
Summary	Objective: We analyzed the operative cases for the primary gastric cancer taking warfarin in order to investigate the safety and complication in association with anticoagulation therapy. Methods: 15 patients taking warfarin who underwent gastrectomy for the gastric cancer at our department from year 1998 to 2010 were retrospectively analyzed. Results: There were 12 men and 3 women. The mean age was 69 years old. Warfarin potassium was discontinued preoperatively in all cases, and heparin was administered until 6 hours prior to the operation, and readeministered after the operation. The value of activated partial thromboplastin time was used to monitor the effect of heparin. There were 11 distal gastrectomy, 2 proximal gastrectomy, 2 total gastrectomy, and mean amounts of intraoperative bleeding were 264ml, 225ml, and 225ml, respectively. The mean duration of postoperative hospitalization was 24.7 days, 21 days and 18.5 days, respectively. There was no major postoperative bleeding, however, there were one case which developed pneumonia and ileus, postoperatively, and one case with anastomotic stenosis. Surgery for gastric cancer patients taking warfarin potassium showed no evident increase of operation time, intraoperative bleeding and duration of hospitalization, compared to that of all gastric cancer patients operated at our department. Conclusions: Surgery for gastric cancer patients taking warfarin potassium could be performed comparatively safe by paying attention to the status of blood coagulation and careful perioperative management.