SHIMADA ERIKO    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Assistant Professor
Language	English
Title	Long-Term Outcomes of the Fontan Operation: Forty Years of Experience at a Single Institute
Conference	The 81st Annual Scientific Meeting of the Japanese Circulation Society (JCS2017)
Promoters	Japanese Circulation Society
Conference Type	Nationwide Conferences
Presentation Type	Speech
Lecture Type	General
Publisher and common publisher	◎MORI Hiroki, SHIMADA Eriko, SHINOHARA Tokuko, INAI Kei, NAKANISHI Toshio
Date	2017/03/18
Venue (city and name of the country)	Kanazawa, JAPAN
Society abstract	PROGRAM JCS 2017 309
Summary	Introduction: Although the survival rate of individuals with single-ventricular hearts has been dramatically improved by the Fontan operation, the long-term prognosis is as yet unclear. Purpose: To clarify the long-term outcomes of the Fontan operation and to describe the clinical condition of long-term survivors. Design and Setting: Retrospective observational study set at a single institute. Methods: We analyzed 628 patients who had undergone the Fontan procedure in our institute between 1974 and 2013. Results: Overall, survival rate declines about 10% every 10 years. Forty-five patients underwent the Fontan operation more than 30 years ago; of these, 20 are alive and 25 have died. All long-term survivors had heart failure (NYHA I:0, II:17, III:3, IV:0). Nineteen (95%) of the 20 long-term survivors had a history of atrial tachycardia and 11 (40%) have had at least one thromboembolic event. Conclusion: Prognosis of the Fontan operation has improved in recent years. Further refinement of this treatment strategy is needed to improve event-free survival.