KAWAGUCHI Yuuki
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Assistant Professor |
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Language | English |
Title | Decreased risk of dialysis-related amyloidosis in the 2010s: Results from Japanese nationwide surveys in 2010 and 2017 |
Conference | Kidney Week 2024 |
Promoters | American Society of Nephrology |
Conference Type | International society and overseas society |
Presentation Type | Poster notice |
Lecture Type | General |
Publisher and common publisher | ◎Hoshino Junichi, Ushio Yusuke, Kawaguchi Yuki, Manabe Shun, Kataoka Hiroshi, Yamamoto Suguru, Abe Masanori, Hanafusa Norio, |
Date | 2024/10/25 |
Country | United States |
Venue (city and name of the country) |
San Diego, USA |
Holding period | 2024/10/24~2024/10/27 |
Summary | Background
Incidences and risk factors of dialysis-related amyloidosis may be changed with improvement of dialysis technologies. In this study, we aimed to clarify recent incidences of operation of carpal tunnel syndrome (CTS) by using two large-scale data. Methods We used the Japan Renal Data Registries for 2010 and 2017 to compare the crude risk of CTS during the following year, excluding patients with a history of CTS, those who received temporary dialysis or transplantation, and those whose data were incomplete or outliners. The crude risks of new CTS among every 5 years of dialysis vintage up to 35 years or more in the 2010 and 2017 cohorts were analyzed. Results A total of 167,793 patients in the 2010 cohort (female, 37%; mean age, 67.4±12.5 years; and mean dialysis vintage, 7.2±6.5 years) and 164,102 patients in the 2017 cohort (female, 35%; mean age, 69.6±12.4 years; and mean dialysis vintage, 7.6±7.0 years) were analyzed. Of the 2010 patients, 1.31% experienced first-time CTS compared with 1.53% of the 2017 cohort. In the 2017 cohort, the crude risks among dialysis vintage 15-20, 20-25, 25-30, 30-35, and over 35 years were 3.2 (95%CI, 2.9-3.5), 6.5 (5.9-7.2), 10.8 (9.7-11.9), 18.3 (16.3-20.5), and 26.3 (23.2-29.6)%, respectively. Those risks were reduced up to 30% from the same dialysis vintage in the 2010 cohort, though the difference was very small in patients with vintage over 35 years. Conclusion We previously reported the incidence of first-time onset of CTS was significantly reduced from 1998 to 2010, especially for patients with longer dialysis vintage. The incidence of CTS was also reduced from 2010 to 2017 among the same vintage group, though the degree of reduction was smaller than the previous decade and not observed in patients with dialysis vintage over 35 years. |