TAKADA Takuma    Department   Research Institutes and Facilities, Research Institutes and Facilities    Position   Assistant Professor
Language	English
Title	Comparison of Clinical Characteristics and Outcomes of Venous Thromboembolism (VTE) between Young and Elder Patients: From the COMMAND VTE Registry-2
Conference	第87回日本循環器学会学術集会
Conference Type	Nationwide Conferences
Presentation Type	Speech
Lecture Type	General
Publisher and common publisher	Kenta Mori, Kazunori Otsui, Mitsumasa Okano, Ryuki Chatani, Kazuhisa Kaneda, Yuji Nishimoto, Nobutaka Ikeda, Yohei Kobayashi, Satoshi Ikeda, Kite Kim, Toru Takase, Maki Ohi, Takuma Takada, Jiro Sakamoto, Yoshito Ogihara, Yugo Yamashita
Date	2023/03/11
Venue (city and name of the country)	福岡
Summary	Background: It remains unclear, in VTE patients between young and elder individually, what is the optimized strategy of anti-coagulant therapy, furthermore, what is the most important risk of mortality. Methods: In the COMMAND VTE Registry-2; multicenter registry enrolling 5197 VTE patients, we categorized patients into two age groups: less than 71 years (Young Grp) and 71 years and above (Elder Grp)(n=2691 and 2506, 56.0±12.6 and 80.3±5.6 yrs). Kaplan-Meier and Cox multivariate regression analyses were done using mortality risk and variables; sex, obesity, active cancer, heart failure, marker of VTE; D-dimer, recurrent VTE and major bleeding. Results: Compared with Young Grp, Elder Grp was lower survival rate in with or without active cancer as shown in figure. Furthermore, we found the relationship of all-cause mortality with active cancer and major bleeding in both groups, and heart failure in Young Grp, but obesity in Elder Grp. Conclusions: The clinical characteristics differed between young and elder groups, there was the difference in the risks; heart failure and obesity for mortality.