ヤマグチ　ジユンイチ   YAMAGUCHI Jiyun'ichi   山口　淳一    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
言語種別	英語
発表タイトル	Novel prognostic value of PARIS score in patients after rotational atherectomy to the severely calcified coronary artery
会議名	Euro PCR 2018
主催者	European Society of Cardiology
学会区分	国際学会及び海外の学会
発表形式	ポスター掲示
講演区分	一般
発表者・共同発表者	◎TANAKA Kazuki, JUJO Kentaro, KONAMI Yutaka, OOTSUKI Hisao, NAKAO Masashi, ARASHI Hiroyuki, YAMAGUCHI Junichi, HAGIWARA Nobuhisa
発表年月日	2018/05/23
開催地 （都市, 国名）	Paris, FRANCE
概要	AIMS Rotational atherectomy (RA) is a promising strategic option for technical success of percutaneous coronary intervention (PCI) to severely calcified lesions. However, long-term clinical prognosis after RA has not been fully discussed in the drug-eluting stent (DES) era. PARIS score can separately predict embolic and bleeding events after PCI. We aimed to validate PARIS score in predicting clinical outcomes of patients who were treated with RA. METHODS AND RESULTS Total of 404 patients undergoing PCI with RA between 2004 and 2013 was enrolled. Median follow-up period was 1,521 days. The rate of coronary thrombotic events (CTEs: stent thrombosis and myocardial infarction) and major adverse cardiac events (MACE: CTEs, cardiovascular death, and target vascular revascularization) were compared among patients with PARIS-CTEs low (n=123), intermediate (n=109), and high (n=172) score group. Additionally, incidence of major bleeding (MB) was also compared among PARIS-MB low (n=35), intermediate (n=159), and high (n=210) score group.As a result, Kaplan-Meier analysis revealed that both rates of CTEs and MB were comparable among the groups (4-year CTEs: 4.2%, 9.2%, 7.5%, p=0.11, MB: 7.2%, 5.5%, 10.0%, p=0.22). In contrast, MACE rate was significantly higher in the higher PARIS-CTEs score group (4-year MACE: 22.8%, 44.4%, 52.5%, p<0.001). CONCLUSIONS PARIS score may predict long-term MACE, but not each of CTEs or bleeding events in patients after RA in the DES era.