コヤナギ　チヒロ   Koyanagi Chihiro   小栁　千紘    所属   医学部 医学科（東京女子医科大学病院）    職種   助教
言語種別	日本語
発表タイトル	Ratio of Systolic Function-to-Pressure of Right Ventricule Predicts Mortality in Acute Heart Failure Patients with Left Ventricular Systolic Dysfunction
会議名	第83回日本循環器学会学術集会
主催者	日本循環器学会
学会区分	全国規模の学会
発表形式	ポスター掲示
講演区分	一般
発表者・共同発表者	◎亀谷智子, 重城健太郎, 齋藤千紘, 新井光太郎, 南雄一郎, 阿部拓朗, 芦原京美, 萩原誠久
発表年月日	2019/03/31
開催地 （都市, 国名）	横浜市
概要	*Poster Session (Japanese)115 Heart Failure (Laboratory/Biomarkers) BACKGROUND: Right ventricular (RV) systolic function and systolic pressure respectively affects prognosis in acute heart failure (AHF) patients with reduced left ventricular ejection fraction (LVEF). We aimed to evaluate the prognostic value of RV systolic function index in combination with RV systolic pressure (RVSP) in AHF patients. METHODS and RESULTS: This observational study included 548 urgently hospitalized AHF patients with reduced LVEF and with full information of tissue Doppler imaging (TDI) echocardiography. ROC curves for all-cause mortality, as the primary endpoint, indicated higher AUC in the ratio of RV-TDI s’ to RVSP, compared to other indices of RV systolic function. When dividing patients into 2 groups by the cut-off value of RV-TDI s’/RVSP (0.21), KaplanMeier analysis showed higher mortality in patients with RVTDI s’/RVSP<0.21 (Figure). In multivariate Cox regression analysis, RV-TDI s’/RVSP<0.21 was an independent predictor of all-cause mortality in AHF patients with reduced LVEF (HR: 2.50 [95%CI: 1.39-4.50]), even after adjustment for confounders.CONCLUSIONS: The ratio of RVTDI s’/RVSP may predict all-cause mortality in AHF patients with reduced LVEF.