ヤマグチ ジユンイチ   YAMAGUCHI Jiyun'ichi
  山口 淳一
   所属   医学部 医学科(東京女子医科大学病院)
   職種   教授・基幹分野長
言語種別 英語
発表タイトル Impact of Renal Transplantation on Clinical Outcomes after Percutaneous Coronary Intervention
会議名 The 83rd Annual Scientific Meeting of the Japanese Circulation Society (JCS2019)
主催者 Japanese Circulation Society
学会区分 全国規模の学会
発表形式 口頭
講演区分 一般
発表者・共同発表者◎SATOMI Natsuko, NAKAO Masashi, EBIHARA Suguru, TANAKA Kazuki, OOTSUKI Hisao, YAMAGUCHI Junichi, HAGIWARA Nobuhisa
発表年月日 2019/03/30
開催地
(都市, 国名)
Yokohama, JAPAN
概要 *Featured Research Session 6 Coronary Artery Diseases (Clinical) 2

Introduction: Renal transplantation (RTx) is one of the great options for hemodialysis (HD) patients to improve their life expectancy. However, little is known about outcomes of RTx patients undergoing percutaneous coronary intervention (PCI).

Methods: Consecutive 50 RTx patients undergoing PCI from 2002 to 2017 were enrolled. We examined clinical outcomes of RTx patients in comparison with those of 50 HD patients who underwent PCI using propensity score matching. The primary outcome was the incidence of major adverse cardiac event (MACE: a composite of all cause death, non-fatal myocardial infarction and target vessel revascularization [TVR]).

Results: Kaplan-Meier analysis revealed that the incidence of MACE in RTx group was significantly lower than in HD group (p<0.0001). Moreover, RTx group was associated with lower risk for all cause death (odds ratio [OR]: 0.23; 95% confidence interval [CI]: 0.05 to 0.72; p=0.01) and TVR (OR: 0.12; 95% CI: 0.04 to 0.29; p<0.0001) than HD group.Conclusion: Our present results suggest that RTx may improve not only life expectancy but also TVR after PCI.