ヤマグチ　ジユンイチ   YAMAGUCHI Jiyun'ichi   山口　淳一    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
言語種別	英語
発表タイトル	Antithrombotic Therapy in Atrial Fibrillation Patients with Chronic Kidney Disease Undergoing Percutaneous Coronary Intervention-From Multicenter Cohort Study-
会議名	The 79th Annual Scientific Meeting of the Japanese Circulation Society
主催者	Japanese Circulation Society
学会区分	全国規模の学会
発表形式	口頭
講演区分	一般
発表者・共同発表者	◎OOTSUKI Hisao, WATANABE Misahiro, KAMISHIMA Kazuho, OKAYAMA Dai, HARUKI Shintaro, JUJO Kentaro, ARASHI Hiroyuki, MINAMI Yuichiro, TAKAGI Atsushi, OOTA Yoshimi, TANAKA Hiroyuki, MORI Fumiaki, FUJII Shinya, HONDA Atsushi, YAMAGUCHI Junichi, HAGIWARA Nobuhisa
発表年月日	2015/04/25
開催地 （都市, 国名）	Osaka, JAPAN
学会抄録	PROGRAM JCS 2015 503
概要	Background: The relation between antithrombotic therapy and prognosis in atrial fibrillation (AF) patients with chronic kidney disease (CKD) undergoing percutaneous coronary intervention (PCI) is unclear. Methods and Results: Consecutive 450 patients with AF undergoing PCI were enrolled at 8 medical centers. Among them, we examined 198 patients with CKD (eGFR < 60ml/min/1.73m2, without maintenance hemodialysis), including 130 patients (66%) on triple therapy (TT; warfarin + dual antiplatelet therapy [DAPT]) and 68 patients (34%) on DAPT at the time of PCI. The incidence of major adverse cerebro-cardiovascular events (MACCE; cardiac death, non-fatal myocardial infarction and stroke) and bleeding complications were evaluated. Patient´s characteristics and Kaplan-Meier curve of clinical outcomes are shown below. Conclusion: AF patients with CKD on TT had similar incidence of MACCE but more bleeding complications compared to DAPT patients.