サカイ　シユウジ   SAKAI Shiyuuji   坂井　修二    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
言語種別	日本語
発表タイトル	Prediction of Liver Congestion after Fontan Operation Using Vortex Flow Map of Cardiac Cine MR Imaging
会議名	第81回日本循環器学会学術集会
主催者	日本循環器学会
学会区分	全国規模の学会
発表形式	ポスター掲示
講演区分	一般
発表者・共同発表者	◎長尾充展, 高橋辰徳, 椎名由美, 稲井慶, 朴仁三, 福島賢慈, 坂井修二
発表年月日	2017/03/19
開催地 （都市, 国名）	金沢市
学会抄録	第81回日本循環器学会学術集会　プログラム集 449
概要	Introduction: Patients with congenital heart disease corrected by Fontan‒operation have liver congestion (LC) that progresses to fibrosis with late complications. Objective: To investigate whether LC can be predicted by flow dynamics in Fontan-passway. Methods: 28 patients after arterio-pulmonary connection Fontan-operation who underwent cardiac MRI and the following contrast-enhanced CT were enrolled. We developed a vortex flow map that can quantify vortex flow index (VFI, %) in Fontan-passway from conventional cine MRI (Figure). LC was identified as abnormal parenchymal enhancement and cirrhotic signs on CT. Results: VFI was significantly smaller for patients with LC than those without (9% vs. 26%, p<0.01). The optimal cutoff of 16% VFI can predict LC patients, with 82% sensitivity and 80% specificity. Conclusion: LC after Fontan-operation can be predicted by vortex flow in Fontan-passway.