エジマ　コウイチロウ   Ejima Kouichirou   江島　浩一郎    所属   医学部 医学科（東京女子医科大学病院）    職種   寄附部門准教授
言語種別	英語
発表タイトル	Impact of Rapid Ventricular Tachycardia Stability on the Effectiveness of Antitachycardia Pacing Therapy before Defibrillation
会議名	The 81st Annual Scientific Meeting of the Japanese Circulation Society (JCS2017)
主催者	Japanese Circulation Society
学会区分	全国規模の学会
発表形式	口頭
講演区分	一般
発表者・共同発表者	◎YAGISHITA Daigo, SHODA Morio, EJIMA Koichiro, IWANAMI Yuji, HENMI Ryuta, HAGIWARA Nobuhisa
発表年月日	2017/03/17
開催地 （都市, 国名）	Kanazawa, JAPAN
学会抄録	PROGRAM JCS 2017 208
概要	Background: Antitachycardia pacing before defibrillation (ATP-BD) could potentially terminate fast ventricular tachycardia (FVT) detected in ventricular fibrillation zone (VFZ) in patients implanted with ICD or CRTD. Tachycardia cycle length (TCL) has been reported as a predictor of successful FVT termination by ATP-BD, however, the tachycardia stability has not been well investigated. Methods: This study consisted of 212 patients implanted with Biotronik ICD/CRTD since May 2008 until July 2016 in our institution. A total of 212 appropriate VFZ episodes was recorded in 31 patients. Thirty-three ATP-BD episodes in 11 patients with structural heart disease were investigated. Tachycardia stability (TS) was automatically calculated as a maximum time difference between the TCL among the last four beats before ATP-BD as well as the average of TCL. Results: Eighteen successful termination episodes (54.5%) were observed among 33 ATP-BD episodes. The TCL was significantly longer and the TS was significantly smaller in successful episodes than unsuccessful episodes (292.2±17.8ms vs. 259.9±32.9ms, p<0.01, 9.7±6.2ms vs. 14.5±7.0ms, p<0.05, respectively). The percentage of TS in the TCL (TS) was also significantly smaller in successful episodes (3.3±2.2% vs.5.7±2.7%, p<0.01). The predictive cut-off value in TCL was 270ms (sensitivity=83.3%, specificity=60.0%, p<0.01, AUC=0.83), and %TS was 3.6% (sensitivity=77.8%, specificity=60.0%, p<0.05, AUC=0.73). Conclusion: TCL and TS could be the important factors for successful FVT termination by ATP-BD in patients with an ICD/CRTD.