イシダ　イツセイ   Ishida Itsusei   石田　一世    所属   医学部 医学科（東京女子医科大学病院）    職種   助教
言語種別	英語
発表タイトル	The Effects of Predilation with Scoring Balloon Compared to Conventional Balloon on Cobaltchromium Stent Expansion Analyzed with Optical Coherent Tomography
会議名	The 79th Annual Scientific Meeting of the Japanese Circulation Society
主催者	Japanese Circulation Society
学会区分	全国規模の学会
発表形式	ポスター掲示
講演区分	一般
発表者・共同発表者	◎JUJO Kentaro, KIM Ahsung, ISHIDA Issei, SUZUKI Yuki, SAITO Katsumi, HAGIWARA Nobuhisa
発表年月日	2015/04/25
開催地 （都市, 国名）	Osaka, JAPAN
概要	Background: Stent expansion remains one of important predictors of restenosis and subacute thrombosis, even in use of drug-eluting stent. In addition, the bioresorbable vascular scaffold requires sufficient lesion preparation for their appropriate apposition.Methods and Results: Sixty-six consecutive de novo lesions were enrolled, and finally 52 non-calcified lesions treated with Cobalt-chromium Everolimus-eluting stent under optical coherent tomography (OCT) guidance without post-stenting dilation. Enrolled lesions randomly assigned to be performed single predilation either with semi-compliant scoring or conventional balloon. Stent expansion was defined as the ratio of OCT-measured minimum/predicted stent area. This ratio was significantly larger in scoring group (71 vs. 61%, p=0.017), and greater percentages of stents had final minimum stent areas >5.0 mm2 (27 vs. 4%, p=0.021). Larger degrees of dissection-angle after balloon dilation was significantly more prevalent in scoring group (p=0.030), and degrees of dissection positively associated with stent expansion in lesion with >90 degree dissection (r2=0.28, p=0.044). Quantitative coronary angiography (QCA) revealed similar expansion at stent deployment (80 vs. 75 %, p=0.10) followed with significantly larger minimum stent diameter in scoring group on final angiography (2.43 vs. 2.27 mm, p=0.049), suggesting that lesion modification by scoring device may avoid acute stent recoil even in non-calcified lesions.Conclusion: In this randomized study, pretreatment with scoring balloon enhanced stent expansion and minimized the difference between predicted and achieved stent dimension.