セキグチ　ハルキ   SEKIGUCHI Haruki   関口　治樹    所属   医学部 医学科（東京女子医科大学病院）    職種   准教授
言語種別	日本語
発表タイトル	Prevalence and Characteristics of Myocardial Crypts Referred for Cardiovascular Magnetic Resonance
会議名	第79回日本循環器学会学術集会
主催者	日本循環器学会
学会区分	全国規模の学会
発表形式	ポスター掲示
講演区分	一般
発表者・共同発表者	◎渡邉絵里, 高橋夕芙子, 藤田悦子, 木村眞樹子, 関口治樹, 谷口藤緒, 高良綾子, 石塚尚子, 志賀剛, 島本健, 川名正敏
発表年月日	2015/04/24
開催地 （都市, 国名）	大阪市
学会抄録	第79回日本循環器学会学術集会　プログラム集 227
概要	Background: Recently myocardial crypts are detected by cardiovascular magnetic resonance(CMR). A higher prevalence of crypts in patients and gene carrier with hypertrophic cardiomyopathy(HCM) was shown and crypts seem relatively common in the normal population in western countries. Purpose: We investigate the prevalence and characteristics of myocardial crypts in Japanese using CMR. Methods: We examined retrospectively 310 consecutive patients referred for CMR. Crypts were defined as >50% invagination into normal myocardium. We performed MRI including cine and late gadolinium enhancement(LGE) imaging. We investigated the prevalence of crypts, location of crypts and LGE using a 17-segment model, and family history(FH) of patients with crypts. Results: Crypts were identified in 24 patients(7.7%). Thirteen patients were with HCM(54.2%), 7 with cardiomyopathy other than HCM, and 1 with congenital, valvular, coronary artery disease, and normal heart. The prevalence of crypts was significantly higher in patients with HCM(13 of 92:14.1%) than those without HCM(5.0%)(P=0.012). Six patients had multiple crypts. Most popular location was LV basal–inferior wall(19 patients). LGE was found in 10 patients and 2 had LGE in the same segment with crypt. Seven patients had FH of sudden death or LV hypertrophy or cardiomyopathy and 6 of them were patients with HCM. Conclusions: Myocardial crypts were more frequently seen in patients with HCM and also found in patients with other cardiac diseases.