SASAKI Daisuke
   Department   Research Institutes and Facilities, Research Institutes and Facilities
   Position   Assistant Professor (Fixed Term)
Language English
Category Chapter contribution
Title Contractile Force Measurement of Engineered Cardiac Tissues Derived from Human iPS Cells
Book title Pluripotent Stem-Cell Derived Cardiomyocytes, Methods in Molecular Biology book series (MIMB, volume 2320)
ISBN 978-1-0716-1483-9
Editor Yoshinori Yoshida
Edition, Volume, Page pp.161-170
PublisherHumana
Publication place
(City and country)
New York, USA
International coauthorship International coauthorship
Author and coauthor SASAKI Daisuke, MATSUURA Katsuhisa, SHIMIZU Tatsuya
Publication date 2021/07/25
Summary Recent advances in stem cell technologies and tissue engineering are enabling the fabrication of dynamically beating cardiac tissues from human induced pluripotent stem cells. These engineered human cardiac tissues are expected to be used for cardiac regenerative therapies, in vitro drug testing, and pathological investigations. Here we describe the method to fabricate engineered cardiac tissues from human induced pluripotent stem cell-derived cardiomyocytes and to measure the contractile force.