UCHIGATA Yasuko    Department   School of Medicine(Tokyo Women's Medical University Adachi Medical Center), School of Medicine    Position   Professor (Fixed Term)
Article types	Original article
Language	English
Peer review	Peer reviewed
Title	Brachial-ankle pulse wave velocity, but not ankle-brachial index, predicts all-cause mortality in patients with diabetes after lower extremity amputation.
Journal	Formal name：Journal of diabetes investigation Abbreviation：J Diabetes Investig ISSN code：(2040-1124)2040-1116(Linking)
Domestic / Foregin	Foregin
Volume, Issue, Page	8(2),pp.250-253
Author and coauthor	Ikura Kazuki, Hanai Ko, Oka Seiji, Watanabe Makiko, Oda Yuri, Hamada Mariko, Kato Yuka, Shinjyo Takamichi, Uchigata Yasuko
Publication date	2017/03
Summary	We examined whether brachial-ankle pulse wave velocity (baPWV) and ankle-brachial pressure index (ABI) are predictors for mortality in diabetic patients after lower extremity amputation. This was an observational historical cohort study of 102 Japanese diabetic patients after first non-traumatic lower extremity amputation, with a mean age of 63 years (standard deviation 12 years). The end-point was all-cause mortality. During the mean follow-up period of 3.3 years, 44 patients reached the end-point. In both univariate and multivariate analyses, baPWV (m/s) (hazard ratio [HR] 1.05 and 1.04, both P < 0.01, respectively), but not ABI (HR 0.38 and 0.89, P = 0.08 and 0.86, respectively), was a significant predictor for the end-point. When baPWV (above or below the median [21.8 m/s]) and ABI (normal [0.9-1.4] or not) were analyzed as categorical variables, the results were similar. In conclusion, baPWV, but not ABI, might be a predictor for all-cause mortality in diabetic patients after lower extremity amputation.
DOI	10.1111/jdi.12554
PMID	27422213