HIRAMATSU Takeshi    Department   School of Medicine(Yachiyo Medical Center), School of Medicine    Position   Associate Professor
Article types	Original article
Language	English
Peer review	Peer reviewed
Presence of invitation	Invited paper
Title	Long-term Effect of Enlargement of a Ventricular Septal Defect in the Rastelli Procedure.
Journal	Formal name：Seminars in thoracic and cardiovascular surgery Abbreviation：Semin Thorac Cardiovasc Surg ISSN code：15329488/10430679
Domestic / Foregin	Foregin
Volume, Issue, Page	29(2),pp.215-220
Author and coauthor	Toyoda Yasuyuki, Hiramatsu Takeshi, Nagashima Mitsugi, Matsumura Goki, Yamazaki Kenji
Publication date	2017
Summary	We investigated the effect of ventricular septal defect (VSD) enlargement on long-term surgical results, late arrhythmia, and left ventricular (LV) function in the Rastelli procedure for D-transposition of the great arteries with LV outflow tract obstruction (LVOTO). From 1979 to 2001, 74 patients (D-transposition of the great arteries, n = 56; double outlet right ventricle, n = 18) underwent the Rastelli procedure. In group A, 46 patients underwent the Rastelli procedure with VSD enlargement, and in group B, 28 patients underwent the Rastelli procedure without enlargement. There were no hospital deaths. Actuarial survival at 20 years was 80% in group A and 91% in group B (P = 0.50). Freedom from reoperations at 20 years was 40.1% in group A and 52.0% in group B. Reoperations for LVOTO were performed in 2 patients in both groups. In postoperative catheterization, LV ejection fraction in group A was 57.1% ± 8.7% vs 57.2% ± 8.1% in group B (P = 0.97); LV end-diastolic volume, 150.0% ± 47.2% vs 142.0% ± 36.9% of the normal volume (P = 0.97). In long-term postoperative echocardiography, the pressure gradient of the LV to the aorta was 12.0 ± 12.8 vs 17.7 ± 26.0 mm Hg in groups A and B (P = 0.31). There were no differences between the groups regarding basal rhythms, anti-arrhythmic agents, and pacemaker implantation rate. VSD enlargement in the Rastelli procedure can be safely performed without early mortality and with long-term low mortality and morbidity regarding arrhythmia, LV function, and reoperation for late LVOTO. VSD enlargement should be considered as an option for avoiding long-term LVOTO.
DOI	10.1053/j.semtcvs.2017.03.009
PMID	28823332