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野中 学
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor and Division head |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Diagnostic Utility of Polymerase Chain Reaction for Paraffin-embedded Sinus Specimens for Rhinocerebral Mucormycosis Complicated by Internal Carotid Artery Thrombosis and Cerebral Infarction. |
| Journal | Formal name：Internal medicine (Tokyo, Japan) Abbreviation：Intern Med ISSN code：13497235/09182918 |
| Domestic / Foregin | Domestic |
| Volume, Issue, Page | pp.1-4 |
| Total page number | 4 |
| Author and coauthor | Maeda Yukiko, Toda Kunio, Toi Sono, Yano Tetsundo, Iijima Mutsumi, Shimizu Yuko, Nagashima Yoji, Itakura Yasutomo, Iguchi Shigekazu, Kikuchi Ken, Shibuya Kazutoshi, Nonaka Manabu, Kitagawa Kazuo |
| Publication date | 2021/03 |
| Summary | We herein report a 73-year-old man who experienced cerebral infarction caused by infection with a Mucromycocetes species. A delay in anti-fungal treatment might result in a lethal clinical outcome. We were unable to establish an accurate diagnosis based on histological findings and cerebrospinal fluid culture. Therefore, we performed polymerase chain reaction (PCR) using paraffin-embedded specimens, and based on the findings, successfully started administering anti-fungal treatment. We suggest that PCR using sinus specimens be applied when mucormycosis is suspected as an etiology of cerebral infarction and a confirmative diagnosis cannot be established based on the results of pathological examinations or cerebrospinal fluid culture. |
| DOI | 10.2169/internalmedicine.6809-20 |
| PMID | 33678746 |