Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Endowed Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Efficacy of catheter ablation for patients with atrial fibrillation and atrial septal defect.
Journal Formal name:Journal of cardiovascular electrophysiology
Abbreviation:J Cardiovasc Electrophysiol
ISSN code:15408167/10453873
Domestic / ForeginForegin
Volume, Issue, Page 32(2),pp.279-286
Author and coauthor Ogiso Masataka, Ejima Koichiro, Shoda Morio, Sugiyama Hisashi, Kato Ken, Tanaka Hiroyuki, Ohki Hirotaka, Miura Masaru, Hagiwara Nobuhisa
Publication date 2021/02
Summary INTRODUCTION:Given that few studies investigated the efficacy of catheter ablation (CA) in patients with paroxysmal atrial fibrillation (AF) and atrial septal defect (ASD), this study evaluated its effectiveness in patients with paroxysmal AF and ASD.METHODS AND RESULTS:Of the 216 patients who underwent ASD device closure at two hospitals, 36 patients had paroxysmal AF. After April 2012, CA for AF was performed before ASD device closure (ASD-CA group; n = 20). The ASD-CA group had a significantly higher AF-free survival rate after ASD device closure compared to patients without CA for AF before ASD device closure (ASD-non-CA group; n = 16) (ASD-CA group: 2 patients vs. ASD-non-CA group: 9 patients; follow-up period: 4.2 ± 2.5 years; log-rank p = .01). In addition, the AF-free survival rates were similar between the ASD-CA group and 80 paroxysmal AF patients who underwent CA without any detectable structural heart disease (non-SHD-CA group). The two groups were matched by propensity scores for age, sex, and left atrium dimension (ASD-CA group: 2 patients vs. non-SHD-CA group: 5 patients; follow-up period: 3.3 ± 1.8 years; log-rank p = .28).CONCLUSION:CA for AF before ASD device closure might be an effective treatment option for patients with paroxysmal AF and ASD.
DOI 10.1111/jce.14862
PMID 33382508