IIDA Tomohiro
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Original article
Language English
Peer review Peer reviewed
Title Subthreshold 577 nm micropulse laser treatment for central serous chorioretinopathy.
Journal Formal name:PloS one
Abbreviation:PLoS One
ISSN code:19326203/19326203
Domestic / ForeginForegin
Volume, Issue, Page 12(8),pp.e0184112
Author and coauthor Maruko Ichiro, Koizumi Hideki, Hasegawa Taiji, Arakawa Hisaya, Iida Tomohiro
Authorship Last author
Publication date 2017/08
Summary PURPOSE:To compare the efficacy of the subthreshold micropulse laser (SML) to conventional laser (CL) in treating focal leakages of the retinal pigment epithelium (RPE) in the eyes with central serous chorioretinopathy (CSC).METHODS:Twenty-nine eyes of 28 patients with CSC and typical focal leakage were treated with CL or SML. Both treatments were made with a 577 nm yellow laser (CL: NIDEK MC-500, SML: IRIDEX IQ577). The percentage of eyes with a complete resolution, the distance of the laser burns from the fovea, and injury of the RPE after treatment were studied.RESULTS:A complete resolution was seen in 10 of 15 eyes (66.7%) after CL and 9 of 14 eyes (64.3%) after SML (P = 0.89). The average distance from the foveal center to the leakage point was 1282±596 μm for eyes treated with CL and 1271±993 μm for eyes treated with SML (P = 0.4). Only three eyes treated with SML had treatment sites within 500 μm of the fovea. RPE damage determined by fundus autofluorescence was found in all eyes treated with CL and only one eye treated with SML (P<.01).CONCLUSIONS:SML achieved equivalent therapeutic effects as CL but without RPE damage in eyes with CSC.
DOI 10.1371/journal.pone.0184112
PMID 28850595