Nitta Kosaku    Department   Other, Other    Position
Article types	Original article
Language	English
Peer review	Peer reviewed
Title	Bucillamine-induced membranous nephropathy with crescent formation in a patient with rheumatoid arthritis: case report and literature review.
Journal	Formal name：Case reports in nephrology and dialysis Abbreviation：Case Rep Nephrol Dial ISSN code：2296-9705(Electronic)
Volume, Issue, Page	5(1),pp.30-8
Author and coauthor	Manabe Shun†, Banno Mayuko, Nakano Marie, Fujii Teruhiro, Fujiwara Michio, Kita Yasuhiko, Nitta Kosaku, Hatano Michiyasu
Publication date	2015/07
Summary	Bucillamine is a disease-modifying antirheumatic drug that is structurally similar to D-penicillamine. The major renal side effect of bucillamine and D-penicillamine is proteinuria caused by membranous nephropathy (MN). In addition to MN, combined crescent formation has been occasionally reported in D-penicillamine-induced MN, while crescent formation has been rarely reported in bucillamine-treated cases. Here, we describe a 76-year-old female who presented with nephrotic syndrome and rapidly progressive glomerulonephritis. She was receiving bucillamine as initial treatment for recently diagnosed rheumatoid arthritis, and renal biopsy showed MN with crescent formation. To the best of our knowledge, this is the first report of bucillamine-induced MN with crescent formation in the English literature.
DOI	10.1159/000368826
Document No.	25849672